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DRUGS System Improving the Effects of Clinical Pathways: A Systematic Study

  • Systems-Level Quality Improvement
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Abstract

The aim of the study is to assess the feasibility of Drugs Rational Usage Guideline System (DRUGS)-supported clinical pathway (CP) for breast carcinoma, cataract, inguinal hernia and 2-diabetes mellitus whether the application of such a system could improve work efficiency, medical safety, and decrease hospital cost. Four kinds of diseases which included 1773 cases (where 901 cases using paper-based clinical pathways and 872 cases using DRUGS-supported clinical pathways) were selected and their demographic and clinical data were collected. The evaluation criteria were length of stay, preoperative length of stay, hospital cost, antibiotics prescribed during hospitalization, unscheduled surgery, complications and prognosis. The median total LOS was 1 to 3 days shorter in the DRUGS-supported CP group as compared to the Paper-based CP group for all types (p < 0.05). Totel hospital cost decreased significantly in the DRUGS-supported CP group than that in Paper-based CP group. About antibiotics prescribed during hospitalization, there were no statistically differences in the time of initial dose of antibiotic and the duration of administration except the choice of antibiotic categories. The proportion of DRUGS-supported clinical pathway conditions where a broad-spectrum antibiotic was prescribed decreased from 63.6 to 34.5 % (p < 0.01) in the Paper-based group. While after the intervention, the differences were statistically not significant in unscheduled surgery, complications and prognosis. In this study, DRUGS-supported clinical pathway for breast carcinoma, cataract, inguinal hernia, 2-diabetes mellitus was smoothly shifted from a paper-based to an electronic system, and confer benefits at the hospital level.

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References

  1. Pearson, S. D., Goulart-Fisher, D., and Lee, T. H., Critical pathways as a strategy for improving care: problems and potential. Ann. Intern. Med. 123(12):941–948, 1995.

    Article  CAS  PubMed  Google Scholar 

  2. Darer, J., Pronovost, P., and Bass, E. B., Use and evaluation of critical pathways in hospitals. Eff Clin Pract. 5:114–119, 2002.

    PubMed  Google Scholar 

  3. Kim, S., Losina, E., Solomon, D. H., Wright, J., and Katz, J. N., Effectiveness of clinical pathways for total knee and total hip arthroplasty: Literature review. Am. J. Art Ther. 18:69–74, 2003.

    Google Scholar 

  4. Panella, M., Marchisio, S., and Di Stanislao, F., Reducing clinical variations with clinical pathways: do pathways work? Int. J. Qual. Health Care 15:509–521, 2003.

    Article  CAS  PubMed  Google Scholar 

  5. Vanhaecht, K., Sermeus, W., Tuerlinckx, G., Witters, I., Vandenneucker, H., and Bellemans, J., Development of a clinical pathway for total knee arthroplasty and the effect on length of stay and in-hospital functional outcome. Acta Orthop. Belg. 71(4):439–444, 2005.

    PubMed  Google Scholar 

  6. Vanhaecht, K., Bellemans, J., De Witte, K., Diya, L., Lesaffre, E., and Sermeus, W., Does the organization of care process affect outcome in patients undergoing total joint arthroplasty? J. Eval. Clin. Pract. 16(1):121–128, 2010.

    Article  PubMed  Google Scholar 

  7. Roeder, N., Hensen, P., Hindle, D., Loskamp, N., and Lakomek, H. J., Clinical pathways: effective and efficient inpatient treatment. Chirurg 74(12):1149–1155, 2003.

    Article  CAS  PubMed  Google Scholar 

  8. Panella, M., Marchisio, S., Brambilla, R., Vanhaecht, K., and Di Stanislao, F., A cluster randomized trial to assess the effect of clinical pathways for patients with stroke: results of the clinical pathways for effective and appropriate care study. BMC Med. 10:71–83, 2012.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Sheffield, K. M., Ramos, K. E., Djukom, C. D., Jimenez, C. J., Mileski, W. J., Kimbrough, T. D., Townsend, C. M., Jr., and Riall, T. S., Implementation of a critical pathway for complicated gallstone disease: translation of population-based data into clinical practice. J. Am. Coll. Surg. 212(5):835–843, 2011.

    Article  PubMed Central  PubMed  Google Scholar 

  10. Steinacher, B., Mausolff, L., and Gusy, B., The effects of a clinical care pathway for schizophrenia. Dtsch. Arztebl. Int. 109(46):788–94, 2012.

    PubMed Central  PubMed  Google Scholar 

  11. Norton, S. P., Pusic, M. V., Taha, F., Heathcote, S., and Carleton, B. C., Effect of a clinical pathway on the hospitalisation rates of children with asthma: a prospective study. Arch. Dis. Child. 92:60–66, 2007.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  12. Munitiz, V., Martinez-de-Haro, L. F., Ortiz, A., Ruiz-de-Angulo, D., Pastor, P., and Parrilla, P., Effectiveness of a written clinical pathway for enhanced recovery after transthoracic (Ivor Lewis) oesophagectomy. Br. J. Surg. 97(5):714–718, 2010.

    Article  CAS  PubMed  Google Scholar 

  13. Ronellenfitsch, U., Schwarzbach, M., Kring, A., Kienle, P., Post, S., and Hasenberg, T., The effect of clinical pathways for bariatric surgery on perioperative quality of care. Obes. Surg. 22(5):732–739, 2012.

    Article  PubMed  Google Scholar 

  14. Hardt, J., Schwarzbach, M., Hasenberg, T., Post, S., Kienle, P., and Ronellenfitsch, U., The effect of a clinical pathway for enhanced recovery of rectal resections on perioperative quality of care. Int. J. Color. Dis. 28(7):1019–1026, 2013.

    Article  CAS  Google Scholar 

  15. Yang, Z., Zhao, P., Wang, J., Tong, L., Cao, J., Tian, Y., Yao, Z., Wang, J., Zhu, Y., Jia, Y., and Wen, A., DRUGS system enhancing adherence of Chinese surgeons to antibiotic Use guidelines during perioperative period. PLoS One 9(8), e102226, 2014.

    Article  PubMed Central  PubMed  Google Scholar 

  16. Steinman, M. A., Landefeld, C. S., and Gonzales, R., Predictors of broad-spectrum antibiotic prescribing for acute respiratory tract infections in adult primary care. JAMA 289(6):719–725, 2003.

    Article  PubMed  Google Scholar 

  17. Hirasaki, S., Tanimizu, M., Moriwaki, T., Hyodo, I., Shinji, T., Koide, N., and Shiratori, Y., Efficacy of clinical pathway for the management of mucosal gastric carcinoma treated with endoscopic submucosal dissection using an insulated-tip diathermic knife. Intern. Med. 43(12):1120–1125, 2004.

    Article  PubMed  Google Scholar 

  18. Grol, R., and Grimshaw, J., From best evidence to best practice: effective implementation of change in patients’ care. Lancet 362(9391):1225–1230, 2003.

    Article  PubMed  Google Scholar 

  19. Lomas, J., Sisk, J. E., and Stocking, B., From evidence to practice in the United States, the United Kingdom, and Canada. Milbank Q. 71(3):405–410, 1993.

    Article  CAS  PubMed  Google Scholar 

  20. Cabana, M. D., Rand, C. S., Powe, N. R., Wu, A. W., Wilson, M. H., Abboud, P. A., and Rubin, H. R., Why don’t physicians follow clinical practice guidelines? JAMA 282(15):1458–1465, 1999.

    Article  CAS  PubMed  Google Scholar 

  21. Davis, D. A., and Taylor-Vaisey, A., Translating guidelines into practice: a systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines. CMAJ 157(4):408–416, 1997.

    PubMed Central  CAS  PubMed  Google Scholar 

  22. Grol, R., Successes and failures in the implementation of evidence-based guidelines for clinical practice. Med. Care 39(8 Suppl 2):II46–54, 2001.

    CAS  PubMed  Google Scholar 

  23. Whitman, G., Cowell, V., Parris, K., McCullough, P., Howard, T., Gaughan, J., Karavite, D., Kennedy, M., McInerney, J., and Rose, C., Prophylactic antibiotic use: hardwiring of physician behavior, not education, leads to compliance. J. Am. Coll. Surg. 207(1):88–94, 2008.

    Article  PubMed  Google Scholar 

  24. DiJerome, L., The nursing case management computerized system: meeting the challenge of health care delivery through technology. Comput. Nurs. 10(6):250–258, 1992.

    Article  CAS  PubMed  Google Scholar 

  25. Guven, G. S., and Uzun, O., Principles of good use of antibiotics in hospitals. J. Hosp. Infect. 53(2):91–6, 2003.

    Article  CAS  PubMed  Google Scholar 

  26. Restrepo, M. I., and Frei, C. R., Health economics of use fluoroquinolones to treat patients with community-acquired pneumonia. Am. J. Med. 123(4 Suppl):S39–46, 2010.

    Article  PubMed  Google Scholar 

  27. Hsia, C. Y., Chau, G. Y., King, K. L., Loong, C. C., Lui, W. Y., and Wu, C. W., Factors for prolonged length of stay after elective hepatectomy for hepatocellular carcinoma. The surgeon’s role in the managed care era. Hepato-Gastroenterology 50(51):798–804, 2003.

    PubMed  Google Scholar 

  28. Ibrahim, E. H., Ward, S., Sherman, G., Schaiff, R., Fraser, V. J., and Kollef, M. H., Experience with a clinical guideline for the treatment of ventilator-associated pneumonia. Crit. Care Med. 29(6):1109–1115, 2001.

    Article  CAS  PubMed  Google Scholar 

  29. Soo Hoo, G. W., Wen, Y. E., Nguyen, T. V., and Goetz, M. B., Impact of clinical guidelines in the management of severe hospital-acquired pneumonia. Chest 128(4):2778–2787, 2005.

    Article  PubMed  Google Scholar 

  30. Meyer, E., Buttler, J., Schneider, C., Strehl, E., Schroeren-Boersch, B., Gastmeier, P., Ruden, H., Zentner, J., Daschner, F. D., and Schwab, F., Modified guidelines impact on antibiotic use and costs: duration of treatment for pneumonia in a neurosurgical ICU is reduced. J. Antimicrob. Chemother. 59(6):1148–1154, 2007.

    Article  CAS  PubMed  Google Scholar 

  31. Lancaster, J. W., Lawrence, K. R., Fong, J. J., Doron, S. I., Garpestad, E., Nasraway, S. A., and Devlin, J. W., Impact of an institution-specific hospital-acquired pneumonia protocol on the appropriateness of antibiotic therapy and patient outcomes. Pharmacotherapy 28(7):852–862, 2008.

    Article  PubMed  Google Scholar 

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Correspondence to Jingwen Wang or Aidong Wen.

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Funding

This study was conducted under contract by the Army Science and Technology Major Project in the 11th Five-year Plan (06D007) and Natural Science Foundation of China (No. 81302627, 81302903). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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The authors declare that they have no conflict of interests

Additional information

This article is part of the Topical Collection on Systems-Level Quality Improvement

Shan Wang and Xiaohe Zhu contributed equally to this work.

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Wang, S., Zhu, X., Zhao, X. et al. DRUGS System Improving the Effects of Clinical Pathways: A Systematic Study. J Med Syst 40, 59 (2016). https://doi.org/10.1007/s10916-015-0400-6

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  • DOI: https://doi.org/10.1007/s10916-015-0400-6

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