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Discussion on Brain Structure and Function in Schizophrenia by Multimodal Magnetic Resonance Imaging

  • Image & Signal Processing
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Abstract

In order to explore the relationship between hippocampal structure changes and performance symptoms as well as cognitive function in adolescent schizophrenia, taking the brain response signals of psychiatric patients as the research object, the relationship between hippocampal volume drawn by schizophrenia and language memory of negative symptoms is explored based on morphological analysis method. It is found that the left hippocampal volume of schizophrenic patients is abnormal when the whole brain volume is returned, which is significantly lower than that of normal people. It is also found that the left hippocampus volume of schizophrenic patients is a mediator between negative symptoms and speech memory. The results show that the left hippocampus of schizophrenic patients plays an important role in the pathogenesis of schizophrenia.

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Authors and Affiliations

  1. Department of Medical Imaging, The Fourth Hospital of Harbin Medical University, No.37 Yiyuan Road, Harbin City, 150001, Heilongjiang Province, China

    Xiaohui Zhi & Xuejia Liu

  2. Department of Nursing, The Fourth Hospital of Harbin Medical University, Harbin City, 150001, China

    Lin Cai

  3. Department of Orthopaedics, The Fourth Hospital of Harbin Medical University, Harbin City, 150001, China

    Na Guo

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  1. Xiaohui Zhi
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  2. Lin Cai
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  3. Na Guo
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  4. Xuejia Liu
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Correspondence to Xuejia Liu.

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Author Xiaohui Zhi declares that he has no conflict of interest. Author Lin Cai declares that he has no conflict of interest. Author Na Guo declares that he has no conflict of interest. Author Xuejia Liu declares that he has no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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This article is part of the Topical Collection on Image & Signal Processing

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Zhi, X., Cai, L., Guo, N. et al. Discussion on Brain Structure and Function in Schizophrenia by Multimodal Magnetic Resonance Imaging. J Med Syst 43, 89 (2019). https://doi.org/10.1007/s10916-019-1213-9

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  • DOI: https://doi.org/10.1007/s10916-019-1213-9

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