Skip to main content
Log in

The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests

  • Transactional Processing Systems
  • Published:
Journal of Medical Systems Aims and scope Submit manuscript

Abstract

Pneumatic tube transport systems (PTS) for delivery of patient samples to a hemostasis laboratory are often used to reduce turnaround time for vital analyses. PTS in our hospital has the ability to regulate the transport speed in the range of 3–6 m/s with acceleration control technology. We evaluated the effects of PTS transport for routine coagulation tests, platelet function tests and special global coagulation tests. Duplicate samples were collected from 29 patients and 40 healthy individuals. One sample was sent using PTS and the other was carried by personnel to the lab for determination of protrombin time, activated partial thromboplastin time, trombin time, fibrinogen, antitrombin and thrombin generation test. Platelet function was measured by means of a Apact 4004® analyzer using the inductors (ADP, Arachidonic acid and Epinephrine). Samples transported using PTS with normal transport speed 6 m/s does not affect basic coagulation tests (PT, aPTT, FIB, TT and AT), but TGT has significantly altered. The use of PTS with controlled acceleration regulated the increase in thrombin generation from 10% to 3%, which is not statistically signifiant. The use of PTS with controlled acceleration did not show a significant difference even with the highly sensitive method of platelet aggregation. We conclude that PTS with acceleration control with transport speed from 3 to 6 m/s does not affect to platelet activity as measured by LTA and also global coagulation test - TGT. The advantage of PTS transport is very rapid assessment laboratory testing. From the above validation study, it is clear that PTS should always be validated for specialized laboratory methods and appropriately adapted to specific transport conditions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Vance, L and Mattson, P, Tube Transportation. US Dept. of Transportation, Volpe National Transportation Systems Centre, 1994.

  2. Newton R, Redberger PJ and Round GF, Numerical analysis of some variables determining free flow. Can. J. Chem. Eng. 1963; 42:168–73.

  3. Keshgegian AA and Bull GE, Evaluation of a soft-handling computerized pneumatic tube specimen delivery system: effects on analytical results and turnaround time. American journal of clinical pathology. 1992 ;97(4):535–40.

  4. Tanley PC, Wallas CH, Abram MC and Richardson LD, Use of a pneumatic tube system for delivery of blood bank products and specimens. Transfusion. 1987 Mar 4;27(2):196–8.

  5. Subbarayan D, Choccalingam C, Lakshmi CKA. The Effects of Sample Transport by Pneumatic Tube System on Routine Hematology and Coagulation Tests. Adv Hematol. 2018;2018:6940152.

    Article  Google Scholar 

  6. Nissen PH, Wulff DE, Tørring N, Hvas AM The impact of pneumatic tube transport on whole blood coagulation and platelet function assays. Platelets. 2018; 29(4): 421–424.

  7. Suchsland J, Winter T, Greiser A, Streichert T, Otto B, Mayerle J, Runge S, Kallner A, Nauck M, Petersmann A. Extending laboratory automation to the wards: effect of an innovative pneumatic tube system on diagnostic samples and transport time. Clin Chem Lab Med. 2017; 55(2): 225–230.

  8. Mullins GR, Bruns DE Air bubbles and hemolysis of blood samples during transport by pneumatic tube systems. Clin Chim Acta. 2017; 473: 9–13.

  9. Le Quellec S, Paris M, Nougier C, Sobas F, Rugeri L, Girard S, Bordet JC, Négrier C, Dargaud Y Pre-analytical effects of pneumatic tube system transport on routine haematology and coagulation tests, global coagulation assays and platelet function assays. Thromb Res. 2017; 153: 7–13.

  10. Lippi G, Plebani M, Favaloro EJ Technological advances in the hemostasis laboratory. Semin Thromb Hemost. 2014; 40(2): 178–185.

  11. Glas M, Mauer D, Kassas H, Volk T, Kreuer S Sample transport by pneumatic tube system alters results of multiple electrode aggregometry but not rotational thromboelastometry. Platelets. 2013; 24(6): 454–461.

  12. Martin J, Schuster T,Moessmer G, Kochs EF, Wagner KJ Alterations in rotation thromboelastometry (ROTEM(R)) parameters: point-of-care testing vs analysis after pneumatic tube system transport. Br J Anaesth. 2012; 109(4): 540–545.

  13. Wallin O, Söderberg J, Grankvist K, Jonsson PA,Hultdin J Preanalytical effects of pneumatic tube transport on routine haematology, coagulation parameters, platelet function and global coagulation. Clin Chem Lab Med. 2008; 46(10): 1443–1449.

  14. Enko D, Mangge H, Münch A, Niedrist T, Mahla E, Metzler H, Prüller F Pneumatic tube system transport does not alter platelet function in optical and whole blood aggregometry, prothrombin time, activated partial thromboplastin time, platelet count and fibrinogen in patients on anti-platelet drug therapy. Biochem Med (Zagreb). 2017; 27(1): 217–224.

  15. Zilberman-Rudenko J, Zhao FZ, Reitsma SE, Mitrugno A, Pang J, Shatzel JJ, Rick B, Tyrrell C, Hasan W, McCarty OJT, Schreiber MA. Effect of Pneumatic Tubing System Transport on Platelet Apheresis Units. Cardiovasc Eng Technol. 2018:515–527.

Download references

Funding

Supported by grant LF-2020-002 and MH CZ - DRO (FNOl, 00098892).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Luděk Slavík.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Transactional Processing Systems

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Slavík, L., Úlehlová, J., Bradáčová, P. et al. The Modern Pneumatic Tube System Transports with Reduced Speed Does Not Affect Special Coagulation Tests. J Med Syst 44, 142 (2020). https://doi.org/10.1007/s10916-020-01614-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10916-020-01614-6

Keywords

Navigation