Skip to main content
Log in

Segmentation of brain MR images using a proper combination of DCS based method with MRF

  • Published:
Multimedia Tools and Applications Aims and scope Submit manuscript

Abstract

Manual segmentation of Magnetic Resonance Images (MRI) is a time-consuming process, thus automatic segmentation of brain MR images has attracted more attention in recent years. In this paper, we introduce Dynamic Classifier Selection Markov Random Field (DCSMRF) algorithm for supervised segmentation of brain MR images into three main tissues such as White Matter (WM), Gray Matter (GM) and Cerebrospinal Fluid (CSF). DCSMRF combines a novel ensemble method with the Markov Random Field (MRF) algorithm and tries to obtain the advantages of both algorithms. For the ensemble part of DCSMRF, we propose an ensemble method called Dynamic Classifier System-Weighted Local Accuracy (DCS-WLA) which is a type of Combination of Multiple Classifier (CMC) algorithm. Later, the MRF algorithm is utilized for incorporating spatial, contextual and textural information in this paper. For the MRF section, an energy function based on the output of the DCS-WLA algorithm is proposed, then maximum value for Maximum A Posterior (MAP) criterion is searched to obtain optimal segmentation. The MRF algorithm applies similar to a post processing step in which only a subset of pixels is selected for optimization step. Hence, a vast amount of search space is pruned. Consequently, the computational burden of the proposed algorithm is more tolerable than the conventional MRF-based methods. Moreover, by employing ensemble algorithms, the accuracy and reliability of final results are enhanced compared to the individual methods.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Ahmadvand A, Daliri MR (2014) Brain MR image segmentation methods and applications. OMICS J Radiol (4):3, e130

  2. Ahmadvand A, Daliri MR (2015) Improving the runtime of MRF based method for MRI brain segmentation. Appl Math Comput 256:808–818

    MathSciNet  MATH  Google Scholar 

  3. Ahmadvand A, Kabiri P (2014) Multispectral MRI image segmentation using Markov random field model. SIViP:1–8

  4. Ahmadvand A, Sharififar M, Daliri MR (2015) Supervised segmentation of MRI brain images using combination of multiple classifiers. Australas Phys Eng Sci Med 38(2):241–253

    Article  Google Scholar 

  5. Ahmadvand A et al (2015) A novel CMC based method for MR! brain image segmentation. In 2015 2nd international conference on Knowledge-Based Engineering and Innovation (KBEI). IEEE

  6. Bae MH et al (2009) Automated segmentation of mouse brain images using extended MRF. NeuroImage 46(3):717–725

    Article  Google Scholar 

  7. Bae MH, Wu T, Pan R (2010) Mix-ratio sampling: classifying multiclass imbalanced mouse brain images using support vector machine. Expert Syst Appl 37(7):4955–4965

    Article  Google Scholar 

  8. Balafar M (2012) Gaussian mixture model based segmentation methods for brain MRI images. Artif Intell Rev:1–11

  9. Besag J (1975) Statistical analysis of non-lattice data. Journal of the Royal Statistical Society, Series D (The Statistician) 24(3):179–195

  10. Caldairou B et al (2011) A non-local fuzzy segmentation method: application to brain MRI. Pattern Recogn 44(9):1916–1927

    Article  Google Scholar 

  11. Dubes R et al (1990) MRF model-based algorithms for image segmentation. In Pattern recognition, 1990. Proceedings., 10th international conference on. IEEE

  12. Geman S, Geman D (1984) Stochastic relaxation, Gibbs distributions, and the Bayesian restoration of images. Pattern Anal Mach Intell IEEE Trans 3(6):721–741

    Article  MATH  Google Scholar 

  13. Greenspan H, Ruf A, Goldberger J (2006) Constrained Gaussian mixture model framework for automatic segmentation of MR brain images. Med Imaging IEEE Trans 25(9):1233–1245

    Article  Google Scholar 

  14. Hammersley JM, Clifford P (1971) Markov fields on finite graphs and lattices, (unpublished)

  15. Hashemi RH, Bradley WG, Lisanti CJ (2012) MRI: the basics. Wolters Kluwer Health, Philadelphia

    Google Scholar 

  16. Jiménez-Alaniz JR, Medina-Bañuelos V, Yáñez-Suárez O (2006) Data-driven brain MRI segmentation supported on edge confidence and a priori tissue information. Med Imaging IEEE Trans 25(1):74–83

    Article  Google Scholar 

  17. Kim W, Lee KM (2011) A hybrid approach for MRF optimization problems: combination of stochastic sampling and deterministic algorithms. Comput Vis Image Underst 115(12):1623–1637

    Article  Google Scholar 

  18. Liu Y-T, Zhang H-X, Li P-H (2011) Research on SVM-based MRI image segmentation. J China Univ Posts Telecommun 18:129–132

    Article  Google Scholar 

  19. Marroquín JL et al (2002) An accurate and efficient Bayesian method for automatic segmentation of brain MRI. Med Imaging IEEE Trans 21(8):934–945

    Article  Google Scholar 

  20. Mayer A, Greenspan H (2009) An adaptive mean-shift framework for MRI brain segmentation. Med Imaging IEEE Trans 28(8):1238–1250

    Article  Google Scholar 

  21. Ortiz A et al (2011) MRI brain image segmentation with supervised SOM and probability-based clustering method. In New challenges on bioinspired applications. Springer. p 49–58

  22. Ortiz A et al (2012) Unsupervised neural techniques applied to MR brain image segmentation. AdvArtif Neural Syst 2012:1

    Article  Google Scholar 

  23. Ortiz A et al (2013) Improving MRI segmentation with probabilistic GHSOM and multiobjective optimization. Neurocomputing 114:118–131

    Article  Google Scholar 

  24. Ouadfel S, Batouche M (2003) MRF-based image segmentation using ant colony system. Electron Lett Comput Vision Image Anal 2(2):12–24

    Article  Google Scholar 

  25. Pham D et al (1997) An automated technique for statistical characterization of brain tissues in magnetic resonance imaging. Int J Pattern Recognit Artif Intell 11(08):1189–1211

    Article  Google Scholar 

  26. Platt J (1999) Probabilistic outputs for support vector machines and comparisons to regularized likelihood methods. Adv Large Margin Classif 10(3):61–74

    Google Scholar 

  27. Prakash RM, Kumari RSS (2016) Gaussian mixture model with the inclusion of spatial factor and pixel re-labelling: application to MR brain image segmentation. Arab J Sci Eng:1–11

  28. Qian H, Wu X, Xu Y (2011) Dynamic analysis of crowd behavior. In Intelligent surveillance systems. Springer. p 119–154

  29. Rajapakse JC, Giedd JN, Rapoport JL (1997) Statistical approach to segmentation of single-channel cerebral MR images. Med Imaging IEEE Trans 16(2):176–186

    Article  Google Scholar 

  30. Rivest-Hénault D, Cheriet M (2011) Unsupervised MRI segmentation of brain tissues using a local linear model and level set. Magn Reson Imaging 29(2):243–259

    Article  Google Scholar 

  31. da Silva Ferreira AR (2007) A Dirichlet process mixture model for brain MRI tissue classification. Med Image Anal 11(2):169–182

    Article  Google Scholar 

  32. Siyal MY, Yu L (2005) An intelligent modified fuzzy c-means based algorithm for bias estimation and segmentation of brain MRI. Pattern Recogn Lett 26(13):2052–2062

    Article  Google Scholar 

  33. Tohka J et al (2005) Genetic algorithms for finite mixture model based tissue classification in brain MRI. In Proc. of European medical and biological engineering conference, IFMBE proceedings

  34. Tohka J et al (2007) Genetic algorithms for finite mixture model based voxel classification in neuroimaging. Med Imaging IEEE Trans 26(5):696–711

    Article  Google Scholar 

  35. Vaidyanathan M et al (1995) Comparison of supervised MRI segmentation methods for tumor volume determination during therapy. Magn Reson Imaging 13(5):719–728

    Article  Google Scholar 

  36. Wolpert DH, Macready WG (1997) No free lunch theorems for optimization. IEEE Trans Evol Comput 1:67–82

    Article  Google Scholar 

  37. Woods K, Bowyer K, Kegelmeyer WP Jr (1996) Combination of multiple classifiers using local accuracy estimates. In Computer vision and pattern recognition, 1996. Proceedings CVPR'96, 1996 I.E. computer society conference on. IEEE

  38. Worth AJ (1996)The Internet brain segmentation repository (IBSR), http://www.cma.mgh.Harvard.edu/ibsr

  39. Wu T et al (2012) A prior feature SVM-MRF based method for mouse brain segmentation. NeuroImage 59(3):2298–2306

    Article  Google Scholar 

  40. Yousefi S, Azmi R, Zahedi M (2012) Brain tissue segmentation in MR images based on a hybrid of MRF and social algorithms. Med Image Anal 16(4):840–848

    Article  Google Scholar 

  41. Zhang Y, Brady M, Smith S (2001) Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. Med Imaging IEEE Trans 20(1):45–57

    Article  Google Scholar 

Download references

Acknowledgements

The work has been supported by internal funding from IUST University. No external financial support has been obtained for this work.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohammad Reza Daliri.

Ethics declarations

Conflict of Interest

The authors have no conflicts of interest to declare

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ahmadvand, A., Daliri, M.R. & Zahiri, S.M. Segmentation of brain MR images using a proper combination of DCS based method with MRF. Multimed Tools Appl 77, 8001–8018 (2018). https://doi.org/10.1007/s11042-017-4696-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11042-017-4696-8

Keywords

Navigation