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Auxiliary diagnosis of heterogeneous data of Parkinson’s disease based on improved convolution neural network

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Abstract

Parkinson’s disease (PD) is a kind of nervous system degenerative disease frequently occurring in the elderly over sixty years old. With the development of imaging technology, medical imaging has played a certain role in the diagnosis of Parkinson’s disease. The aim of the paper is to the diagnosis of Parkinson’s disease through deep learning. This paper selects the T2-MRI(T2-Magnetic Resonance Imaging) image and clinical data to diagnose Parkinson’s disease and integrates the heterogeneous data into the improved convolution neural network. In this paper, convolution neural network is added to the Gabor filter to make the whole convolution neural network have better effect; the activation function is improved and adjusted, which means the traditional sigmoid function and the tanh function are discarded, and the Relu activation function is used to improve the neural network. It is proved by experiments that the heterogeneous data diagnosis of T2-MRI image and clinical data (the accuracy is 77.9%) is better than the simple image data diagnosis (the accuracy is71.2%). For the same data, the improved convolution neural network is superior to the traditional network (the accuracy is 64.5%).

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Acknowledgments

The authors acknowledge the Foundation Research Funds for: 1.Youth Program of National Natural Science Foundation of China. “Key Technologies of Early Diagnosis of Alzheimer’s Disease based on Heterogeneous Data Fusion and Brain Network Construction.” (61902058). 2.The Fundamental Research Funds for the Central Universities. “Research on Key Technologies of Early Diagnosis of Encephalitis based on Heterogeneous Data Fusion.” (N2019002). 3.The Fundamental Research Funds for the Central Universities under Grant. (N2024005-2)

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Authors and Affiliations

  1. College of Medical and Bioinformation Engineering, Northeastern University, Shenyang, 110169, China

    Dai Yin, Wenpu Zhao & Xiaoming Hu

  2. China and Engineering Center on Medical Imaging and Intelligent Analysis of Ministry of Education, Northeastern University, Shenyang, 110169, China

    Dai Yin

  3. Faculty of Engineering and Information Technologies, The University of Sydney, Sydney, Australia

    Yiqi Zhao

  4. Neusoft Corporation, Shenyang, China

    Yang Wang

  5. Computer Science School, Northeastern University, Shenyang, China

    Yang Wang

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  1. Dai Yin
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  2. Yiqi Zhao
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  3. Yang Wang
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  4. Wenpu Zhao
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  5. Xiaoming Hu
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Correspondence to Dai Yin.

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Yin, D., Zhao, Y., Wang, Y. et al. Auxiliary diagnosis of heterogeneous data of Parkinson’s disease based on improved convolution neural network. Multimed Tools Appl 79, 24199–24224 (2020). https://doi.org/10.1007/s11042-020-08984-6

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  • DOI: https://doi.org/10.1007/s11042-020-08984-6

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