Skip to main content

Advertisement

Log in

Multi-class classification of breast cancer abnormality using transfer learning

  • Published:
Multimedia Tools and Applications Aims and scope Submit manuscript

Abstract

According to the survey of World Health Organization (WHO), in 2020 there are 2.3 million women found with breast cancer and 685,000 deaths in world wide. 81% women get affected with cancer over the age of 50 at the time of detection. Breast cancer is the world’s number 2 cancer and number 1 cancer in India and 66% survival rate in India is very low if compare to 90% in U.S and 90.2% in Australia. However, treatment for this cancer has possibility of 90% or more. So that, it need to be detect the cancer at very early stage to overcome the death rate. Main objective of this research to design a Breast Cancer diagnose system using image processing and deep learning which can be helpful for radiologist and physician for treating the diagnosis. Basically, Deep learning is a fast-developing fashion inside the health care enterprise and facilitates medical experts to examine records and pick out trends. And image processing plays vital role for enhancing the quality of image by removing noise which is very helpful for better abnormality classification. Now a days Convolution Neural Networks (CNNs) are very popular due to its better performance. In this work, we have used transfer learning with pre-trained VGG16 model. At initial testing stage, the model shows the over-fitting and after that performance improved. Hence we achieved better results by using this approach on DDSM and UPMC data-sets for breast cancer classification. Classifier classify the images into four classes as asymmetry, calcification, carcinoma and mass. Initially 2276 images were taken and divided into 80%-20% ratio. The accuracy achieved by this approach varied from 92% to 95%. We have also used transfer learning with VGG19 and ResNet50 for comparison and found VGG16 much powerful among them. We found, transfer learning with VGG16 giving better results on DDSM and UPMC data-sets. However, breast cancer divided into different categories according to its type, grade or stage of abnormalities, severity of cancer, aggressiveness of cancerous cells, presence/absence of gene etc. Hence classification can be done basis on other types of abnormalities.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9

References

  1. WHO (2021) Breast cancer. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  2. Mathur P, Sathishkumar K, Chaturvedi M, Das P, Sudarshan KL, Santhappan S, Nallasamy V, John A, Narasimhan S, Roselind FS et al (2020) Cancer statistics, 2020: report from national cancer registry programme, India. JCO global oncology 6:1063–1075

    Article  Google Scholar 

  3. Worku B (2017) Breast cancer classification using image processing technique and support vector machine. PhD thesis, St. Mary’s University

  4. Simonyan K, Zisserman A (2014) Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv:1409.1556

  5. He K, Zhang X, Ren S, Sun J (2016) Deep residual learning for image recognition. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp 770–778

  6. Houssein EH, Emam MM, Ali AA, Suganthan PN (2021) Deep and machine learning techniques for medical imaging-based breast cancer: A comprehensive review. Expert Syst Appl 167:114161

    Article  Google Scholar 

  7. Salama WM, Aly MH (2021) Deep learning in mammography images segmentation and classification: Automated cnn approach. Alexandria Eng J 60(5):4701–4709

    Article  Google Scholar 

  8. Szegedy C, Vanhoucke V, Ioffe S, Shlens J, Wojna Z (2016) Rethinking the inception architecture for computer vision. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp 2818–2826

  9. Huang G, Liu Z, Van Der Maaten L, Weinberger KQ (2017) Densely connected convolutional networks. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp 4700–4708

  10. Ronneberger O, Fischer P, Brox T (2015) U-net: Convolutional networks for biomedical image segmentation. In: Medical Image Computing and Computer-Assisted Intervention–MICCAI 2015: 18th International Conference, Munich, Germany, October 5-9, 2015, Proceedings, Part III 18, pp 234–241. Springer

  11. Gupta V, Vasudev M, Doegar A, Sambyal N (2021) Breast cancer detection from histopathology images using modified residual neural networks. Biocybernetics Biomed Eng 41(4):1272–1287

    Article  Google Scholar 

  12. Nazeri K, Aminpour A, Ebrahimi M (2018) Two-stage convolutional neural network for breast cancer histology image classification. In: International conference image analysis and recognition, pp 717–726. Springer

  13. Saber A, Sakr M, Abo-Seida OM, Keshk A, Chen H (2021) A novel deep-learning model for automatic detection and classification of breast cancer using the transfer-learning technique. IEEE Access 9:71194–71209

    Article  Google Scholar 

  14. Kandel I, Castelli M (2020) A novel architecture to classify histopathology images using convolutional neural networks. Appl Sci 10(8):2929

    Article  Google Scholar 

  15. Ouali I, Halima MB, Wali A (2022) Text detection and recognition using augmented reality and deep learning. In: International conference on advanced information networking and applications, pp 13–23. Springer

  16. Ouali I, Halima MB, Ali W (2022) Real-time application for recognition and visualization of arabic words with vowels based dl and ar. In: 2022 International Wireless Communications and Mobile Computing (IWCMC), pp 678–683. IEEE

  17. Zebari DA, Ibrahim DA, Zeebaree DQ, Mohammed MA, Haron H, Zebari NA, Damaševičius R, Maskeliūnas R (2021) Breast cancer detection using mammogram images with improved multi-fractal dimension approach and feature fusion. Appl Sci 11(24):12122

    Article  Google Scholar 

  18. Sheikh TS, Lee Y, Cho M (2020) Histopathological classification of breast cancer images using a multi-scale input and multi-feature network. Cancers 12(8):2031

    Article  Google Scholar 

  19. Araújo T, Aresta G, Castro E, Rouco J, Aguiar P, Eloy C, Polónia A, Campilho A (2017) Classification of breast cancer histology images using convolutional neural networks. PloS one 12(6):0177544

    Article  Google Scholar 

  20. Wang Z, Dong N, Dai W, Rosario SD, Xing EP (2018) Classification of breast cancer histopathological images using convolutional neural networks with hierarchical loss and global pooling. In: International Conference Image Analysis and Recognition, pp 745–753. Springer

  21. Bardou D, Zhang K, Ahmad SM (2018) Classification of breast cancer based on histology images using convolutional neural networks. Ieee Access 6:24680–24693

    Article  Google Scholar 

  22. Alzubaidi L, Al-Shamma O, Fadhel MA, Farhan L, Zhang J, Duan Y (2020) Optimizing the performance of breast cancer classification by employing the same domain transfer learning from hybrid deep convolutional neural network model. Electronics 9(3):445

    Article  Google Scholar 

  23. Al-Haija QA, Adebanjo A (2020) Breast cancer diagnosis in histopathological images using resnet-50 convolutional neural network. In: 2020 IEEE International IOT, electronics and mechatronics conference (IEMTRONICS), pp 1–7. IEEE

  24. Toğaçar M, Özkurt KB, Ergen B, Cömert Z (2020) Breastnet: a novel convolutional neural network model through histopathological images for the diagnosis of breast cancer. Physica A: Statistical Mechanics and its Applications 545:123592

    Article  Google Scholar 

  25. Sethy PK, Pandey C, Khan D, Rafique M, Behera SK, Vijaykumar K, Panigrahi D et al (2021) A cost-effective computer-vision based breast cancer diagnosis. J Intell Fuzzy Syst (Preprint) 1–11

  26. Li X, Shen X, Zhou Y, Wang X, Li T-Q (2020) Classification of breast cancer histopathological images using interleaved densenet with senet (idsnet). PloS one 15(5):0232127

    Article  Google Scholar 

  27. Zewdie ET, Tessema AW, Simegn GL (2021) Classification of breast cancer types, sub-types and grade from histopathological images using deep learning technique. Health and Technology 11(6):1277–1290

    Article  Google Scholar 

  28. UPMC Breast Tomography and FFDM Collection - Downloads available. https://www.dclunie.com/pixelmedimagearchive/upmcdigitalmammotomocollection/index.html

  29. Clark KW, Vendt BA, Smith KE, Freymann J, Kirby J, Koppel P, Moore S, Phillips SR, Maffitt DR, Pringle M, Tarbox L, Prior F (2013) The Cancer Imaging Archive (TCIA): Maintaining and operating a public information repository. J Digit Imaging 26(6):1045–1057. https://doi.org/10.1007/s10278-013-9622-7

    Article  Google Scholar 

  30. Athira P, Fasna K, Krishnan A (2016) An overview of mammogram noise and denoising techniques. Int J Eng Res Gen Sci 4(2):557–563

    Google Scholar 

  31. Heenaye-Mamode Khan M, Boodoo-Jahangeer N, Dullull W, Nathire S, Gao X, Sinha G, Nagwanshi KK (2021) Multi-class classification of breast cancer abnormalities using deep convolutional neural network (cnn). Plos one 16(8):0256500

    Article  Google Scholar 

  32. King A (2022) Image processing. In: Introduction to Medical Physics, pp 447–460. CRC Press, ???

  33. Gustafsson J (2022) 10 image processing. Handbook of Nuclear Medicine and Molecular Imaging for Physicists: Instrumentation and Imaging Procedures I:197

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

All authors have contribution to this manuscript.

Corresponding author

Correspondence to Samayveer Singh.

Ethics declarations

Ethical Statement

This manuscript is not submitted elsewhere before this submission. It is not under review in any of the Journal or Conference before this manuscript submission.

Conflict of Interest

All authors declare that we have no conflict of interest regarding this manuscript.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rani, N., Gupta, D.K. & Singh, S. Multi-class classification of breast cancer abnormality using transfer learning. Multimed Tools Appl 83, 75085–75100 (2024). https://doi.org/10.1007/s11042-023-17832-2

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11042-023-17832-2

Keywords

Navigation