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Examining knowledge entities and its relationships based on citation sentences using a multi-anchor bipartite network

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Abstract

This paper proposes a novel entitymetrics approach by exclusively focusing on citation sentences. Since citation sentences offer authors’ research interest, knowledge entities that appear in such sentences can be considered as key entities. To characterize such key entities, we focus on citation sentences that were extracted from full-text research articles collected from PubMed Central. We used “opioid” as our search query since it is an actively studied domain, which indicates that rigorous amounts of knowledge entities and entity pairs are available for examination. After which we construct two novel citation sentence-based networks, namely the Direct Citation Sentence (DCS) network and the Indirect Citation Sentence (ICS) network. The DCS network is built upon direct entity pairs that are captured within citation sentences. The ICS network, on the other hand, utilized indirect entity cooccurrences based on cited author information and section information. To do this, we propose a multi-anchor bipartite network that uses cited author information and section headings as a multi-anchor that is related to bio-entity nodes, namely the [author/section]-entity bipartite network. To demonstrate the usefulness of the DCS and ICS network, a conventional full-text network is formed for comparison analysis. In addition, during this process, MeSH tree structure is used to examine the bio-entity level characteristics. The results show that DCS and ICS network demonstrate distinct network characteristics and provide unobserved top-ranked bio-entity pairs when compared to traditional method. This indicates that our method can expand the base of entitymetrics and provide new insights for entity level bibliometrics analysis.

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Notes

  1. https://www.springer.com/journal/11192/submission-guidelines#Instructions%20for%20Authors_Title%20Page, last accessed 15 January 2023.

  2. https://www.nlm.nih.gov/mesh/intro_trees.html last accessed 15 January 2023.

  3. MeSH tree structure is a forest rather (composed of 16 single category trees) than a single tree. To calculate the distance (branch count) between MeSH descriptors that were included in different categories, we assumed that the 16 root tree nodes were all connected with each other. We acknowledge that such approach can have limits since some root tree nodes are not closely related with one another (e.g., “Information Science” and “Diseases”). However, it was shown that all the MeSH terms that matched our top-20 bio-entity pair list were included in eight root tree nodes (i.e., “Anatomy”, “Organisms”, “Diseases”, “Chemicals and Drugs”, “Analytical, Diagnostic and Therapeutic Techniques, and Equipment”, “Psychiatry and Psychology”, “Phenomena and Processes”, “Health Care”) that were closely related to each other.

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Acknowledgements

This paper was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2022R1A2B5B02002359). The earlier version of this paper (Nam et al., 2022) was accepted at the 3rd Workshop on Extraction and Evaluation of Knowledge Entities from Scientific Documents (EEKE2022) at the ACM/IEEE Joint Conference on Digital Libraries 2022 (JCDL2022), Cologne, Germany and Online.

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Correspondence to Min Song.

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The corresponding author (Min Song) is a member of the Distinguished Reviewers Board of Scientometrics.

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Appendices

Appendix 1: Top-50 section heading based on frequencies

Section heading

Freq.

%

Section heading

Freq.

%

Discussion

550,001

22.36

Introduction and background

1114

0.05

Introduction

420,851

17.15

Limitations

1013

0.04

Results

141,030

5.75

Diagnosis

963

0.04

Methods

113,141

4.43

Concluding remarks

855

0.03

Materials and methods

101,053

3.75

Main body

850

0.03

Background

79,623

3.24

Mechanism of action

834

0.03

Results and discussion

31,899

1.30

Pharmacological activities

823

0.03

Conclusions

12,597

0.52

Mapping and ablation

821

0.03

Review

11,080

0.45

Recommendations

753

0.03

Methodsdesign

4814

0.20

Subjects and methods

698

0.03

Discussion and conclusions

3613

0.14

Pathogenesis

689

0.03

Main text

3137

0.13

Rationale

675

0.03

Patients and methods

3091

0.13

Clinical studies

674

0.03

Treatment

3021

0.12

General discussion

665

0.03

Methods and analysis

2643

0.11

Starethods

658

0.03

Methodology

2323

0.09

Pharmacokinetics

638

0.03

Management

1785

0.07

Pharmacology

636

0.03

Experimental section

1780

0.07

Case presentation

631

0.03

Pathophysiology

1558

0.06

Online methods

599

0.02

Findings

1514

0.06

Serotonin

556

0.02

Epidemiology

1420

0.06

Pharmacological activity

529

0.02

Literature review

1338

0.05

Opioids

528

0.02

Future directions

1282

0.05

Overview

522

0.02

Experimental procedures

1210

0.05

Conclusions and future directions

517

0.02

Experimental

1198

0.05

Context

511

0.02

Appendix 2: Excluded entity list

Entity

Freq.

Entity

Freq.

Treatment

526,686

Lead

57,961

Pain

456,305

Oral

57,447

Drug

211,165

Procedure

57,276

FIG

206,186

Procedures

56,578

Care

201,449

Affect

56,073

Response

174,147

Neuronal

54,537

Drugs

168,170

Severity

54,409

Surgery

161,686

Protocol

54,118

Brain

157,926

Condition

54,087

Dose

137,096

Like

53,988

Reduced

127,899

Key

53,656

Function

127,052

Medications

52,639

Therapy

117,437

End

51,958

Human

117,366

Sensitivity

51,654

Blood

106,818

Interest

50,794

Disease

106,162

Secondary

49,189

Opioids

101,146

Rat

48,710

Symptoms

96,081

Distribution

48,064

Support

89,745

Strategies

46,310

Chronic

82,604

Adult

44,728

Stimulation

82,076

Disorders

43,925

Severe

80,434

Delivery

43,609

Exposure

80,109

Line

42,817

Impact

77,239

Side effects

42,242

General

76,767

Right

41,062

Expressed

72,793

Injury

41,590

Acute

71,777

Understanding

40,342

Normal

71,392

Moderate

39,323

Management

68,786

Focus

37,051

Medication

67,976

Diseases

36,224

Measures

67,668

Light

35,968

Association

67,400

Onset

35,871

Concentrations

64,023

Finding

35,413

Central

63,070

Strategy

35,201

Food

62,410

Nervous

34,967

Block

62,157

Activated

34,227

Set

61,710

Content

33,724

Intensity

59,397

  

Appendix 3: Visualization map of conventional full-text cooccurrence network

figure a

Appendix 4: Visualization map of DCS cooccurrence network

figure b

Appendix 5: Visualization map of ICS cooccurrence network

figure c

Appendix 6: Conventional full-text network cooccurrence information

Entity 1

Entity 2

Freq

Distance

Anesthesia

Propofol

5902

10

Methadone

Buprenorphine

5708

6.75

Morphine

Fentanyl

5326

7.25

Mental health

Substance use disorder

5240

5

Substance use disorder

Addiction

4292

4

Anterior

Posterior

3697

Morphine

Oxycodone

3463

8.375

Naloxone

Overdose

3447

10.75

Heroin

Cocaine

3410

8

Kit

RNA

3329

Glucose

Insulin

3225

11

Hip

Fracture

3199

Propofol

Remifentanil

3182

9.5

Anesthesia

Isoflurane

3152

7

Postoperative pain

Pain management

3116

8.5

Anesthesia

Sevoflurane

3093

7.5

Propofol

Sedation

3081

10

Hypotension

Bradycardia

3057

5

CBD

THC

3040

1

Withdrawal

Morphine

3035

9.75

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Nam, D., Kim, J., Yoon, J. et al. Examining knowledge entities and its relationships based on citation sentences using a multi-anchor bipartite network. Scientometrics 129, 7197–7228 (2024). https://doi.org/10.1007/s11192-023-04824-0

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