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Clinical efficacy of computed tomography-guided microwave ablation sequential transcatheter arterial chemoembolization under edge calculation for primary liver cancer over 5 cm in diameter

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Abstract

To explore the clinical efficacy of computed tomography (CT)-guided microwave ablation (MWA) sequential transcatheter arterial chemoembolization (TACE) based on edge calculation for primary liver cancer larger than 5 cm in diameter, CT images based on edge calculation were reconstructed and the model was constructed, and the treatment of the images was evaluated. A total of 30 patients with primary liver cancer over 5 cm in diameter who were admitted to Liaocheng People’s Hospital and Liaocheng Tumor Hospital from January 2020 to January 2021 were randomly divided into TACE group and MWA group. In the CT image processing based on edge computing, appropriate prior information was introduced into the CT reconstruction model to obtain high-quality CT images. The tumor volume, blood supply loss rate, complete necrosis rate, and other indexes of patients treated with TACE alone and TACE combined with MWA were compared. The results showed that CT-guided MWA images were relatively clearer, helping doctors to treat more accurately. There was no considerable difference in survival at 6 months, 12 months, and 36 months between the two groups. In addition, the probability of loss of blood supply, tumor size, and the probability of complete tumor necrosis were not substantially different between the two groups. Subjective evaluation was conducted on the CT image segmentation effect of all patients with liver cancer lesions over 5 cm participating in this study. PSNR and SSIM were higher than other reconstructed model images. After treatment, alpha fetal protein level was substantially lower than before treatment, and alanine aminotransferase and aspartate aminotransferase levels were substantially higher than before treatment, with considerable differences between the two groups. In short, the CT image quality based on edge calculation was improved, which provided a reference for the CT image-guided MWA sequential TACE treatment of primary liver cancer.

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Authors and Affiliations

  1. Department of Interventional Medicine of Liaocheng Tumor Hospital, Liaocheng, 252000, Shandong, China

    Ran Lv

  2. Hospice Unit of Liaocheng People′s Hospital, Liaocheng, 252000, Shandong, China

    Yinpu Tian

  3. Department of Interventional Medicine of Liaocheng People′s Hospital, Liaocheng, 252000, Shandong, China

    Zhen Yu & Chenzhi Liu

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  1. Ran Lv
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  2. Yinpu Tian
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  4. Chenzhi Liu
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Correspondence to Chenzhi Liu.

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Lv, R., Tian, Y., Yu, Z. et al. Clinical efficacy of computed tomography-guided microwave ablation sequential transcatheter arterial chemoembolization under edge calculation for primary liver cancer over 5 cm in diameter. J Supercomput 78, 11298–11317 (2022). https://doi.org/10.1007/s11227-021-04118-3

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  • DOI: https://doi.org/10.1007/s11227-021-04118-3

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