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Wearable wireless real-time cerebral oximeter for measuring regional cerebral oxygen saturation

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Abstract

Monitoring regional cerebral oxygen saturation throughout the perioperative clinical process is important for successful patient outcomes. Cerebral oximeters based on near-infrared spectroscopy (NIRS) have already been used for monitoring brain oxygenation and hemodynamics to avoid intraoperative ischemic stroke and reduce postoperative cognitive dysfunction. The current devices are all designed to be used as a bedside monitor, limiting their use to situations that center around a hospital bed. There is a current lack of wearable, miniaturized, wireless equipment that can extend brain oxygenation monitoring to motion tasks or tight spaces. We design a head-mounted wearable wireless oxygen saturation monitoring on head (WORTH) band based on NIRS for monitoring regional cerebral oxygen saturation. The band is embedded with a highly integrated central block, which comprises an optical module, a microprocessor unit, a wireless communication module, and a power management module. The performance of the WORTH band is evaluated by a controlled hypoxia experiment and a squat-to-stand experiment. The results confirm that the WORTH band can record cerebral oxygen saturation with an accuracy comparable to that of a clinical monitor and demonstrate that it is also effective during motion tasks.

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Acknowledgements

This work was partially supported by National Key Research and Development Program of China (Grant No. 2017YFB1002502), National Natural Science Foundation of China (Grant Nos. 31571003, U1636121), Key Programs of Science and Technology Commission Foundation of Beijing (Grant No. Z181100003818004), Supplementary and Supportive Project for Teachers at Beijing Information Science and Technology University (2018–2020) (Grant No. 5029011103), Beijing Municipal Education Commission Science and Technology Program (Grant Nos. KM202011232008, KM201911232019). We appreciate the English editing assistance of Drs. Rhoda E. and Edmund F. Perozzi.

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Author notes

  1. Si J N and Zhang X contributed equally to this study.

Authors and Affiliations

  1. School of Instrumentation Science and Opto-electronics Engineering, Beijing Information Science and Technology University, Beijing, 100192, China

    Juanning Si, Meng Li, Qing He, Shaohua Chen & Lianqing Zhu

  2. Beijing Key Laboratory for Optoelectronic Measurement Technology, Beijing Information Science and Technology University, Beijing, 100192, China

    Juanning Si, Meng Li, Qing He, Shaohua Chen & Lianqing Zhu

  3. Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China

    Xin Zhang, Jian Yu, Zhiyong Zhang & Tianzi Jiang

  4. National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China

    Xin Zhang, Jian Yu, Zhiyong Zhang & Tianzi Jiang

  5. Research and Development Department, Casibrain Technology Limited Company, Beijing, 100190, China

    Xin Zhang, Jian Yu, Zhiyong Zhang & Tianzi Jiang

  6. Key Laboratory for NeuroInformation of the Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 625014, China

    Tianzi Jiang

  7. Chinese Academy of Sciences Center for Excellence in Brain Science, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China

    Tianzi Jiang

  8. Queensland Brain Institute, University of Queensland, St. Lucia, QL4072, Australia

    Tianzi Jiang

Authors
  1. Juanning Si
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  2. Xin Zhang
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  3. Meng Li
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  4. Jian Yu
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  6. Qing He
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  7. Shaohua Chen
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  8. Lianqing Zhu
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  9. Tianzi Jiang
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Corresponding authors

Correspondence to Lianqing Zhu or Tianzi Jiang.

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Si, J., Zhang, X., Li, M. et al. Wearable wireless real-time cerebral oximeter for measuring regional cerebral oxygen saturation. Sci. China Inf. Sci. 64, 112203 (2021). https://doi.org/10.1007/s11432-020-2995-5

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  • DOI: https://doi.org/10.1007/s11432-020-2995-5

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