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A validation study of a dedicated software for an automated in vivo dosimetry control in radiotherapy

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Abstract

In vivo dosimetry (IVD) is the last step of a radiotherapy quality control program aimed to ensure that the dose delivered is in agreement with that prescribed. IVD procedures based on single detectors are time-consuming and impossible to use for the modern radiotherapy techniques, based on static or kinetic beams (modulated in intensity fluence); this means that more efficient and practical methods are highly recommended. The practical method SOFTDISO, based on the use of electronic portal image device (EPID), provides two tests (i) the R ratio between the reconstructed and the planned isocenter doses to verify an agreement within 5% and (ii) the γ-analysis of the EPID images, to verify γ% ≥ 90% and γmean ≤ 0.4. This paper reports the results of 11,357 IVD tests carried out for 823 patients treated by three-dimensional conformal radiation therapy and volumetric modulated arc therapy techniques. In particular, the dose disagreements are reported distinguishing two kinds of causes, those of (i) class 1 that includes the errors due to inadequate quality controls and (ii) the class 2, due to patient morphological changes. About the tests out of tolerance, 6% were by VMAT and 21% by 3DCRT, but taking into account the only class 1 of errors, i.e., removing the causes of class 2, only 7% of patients examined presented at least one of the three mean indexes out of tolerance. The workload for IVD on 9 patients/day per linac is about 52 min/day but recently, a new automated SOFTDISO version has been implemented to reduce the time to about 34 min/day.

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Authors and Affiliations

  1. Istituto di Fisica, Università Cattolica del Sacro Cuore (UCSC), Rome, Italy

    A. Piermattei, M. Grusio, S. Menna, L. Azario & A. Fidanzio

  2. UOC di Fisica Sanitaria, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy

    A. Piermattei, F. Greco, L. Azario, G. Stimato, E. Placidi, S. Teodoli, A. Porcelli, L. Alberico & A. Fidanzio

  3. UO di Fisica Sanitaria, Fondazione di Ricerca e Cura Giovanni Paolo II, (UCSC), Campobasso, Italy

    S. Cilla

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  1. A. Piermattei
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  2. F. Greco
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  4. S. Menna
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  5. L. Azario
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  11. L. Alberico
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  12. A. Fidanzio
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Correspondence to F. Greco.

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Piermattei, A., Greco, F., Grusio, M. et al. A validation study of a dedicated software for an automated in vivo dosimetry control in radiotherapy. Med Biol Eng Comput 56, 1939–1947 (2018). https://doi.org/10.1007/s11517-018-1822-3

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  • DOI: https://doi.org/10.1007/s11517-018-1822-3

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