Abstract
The purpose of this study is to determine and verify the exact location of radiation therapy fields by using port-film and digital reconstruction radiograph (DRR) as a low-cost tool. Initially, an appropriate algorithm was written for the application of port film in the megavoltage beam irradiation. Detectable contrast was created for the image and then by using appropriate markers and developed written program by MATLAB as DRrPortRegistartion. Semi-automatic and automatic registration between port-film and DRR images were performed for pelvic and chest phantoms. Then, results were compared with electronic portal imaging device (EPID) images in similar conditions. By using this software, DRR and port film as treatment verification tools, the precision of treatment verification and the accuracy of radiation therapy fields were achieved in the extent of the millimeter. Validation results with EPID demonstrated that the mean absolute average error in angle is equal to 0.59 degrees, 1.70 mm in the X-direction, and 2.42 mm in the Y-direction. The results of this study illustrated that using this software and suitable low-cost hardware in the machines without EPID can increase the precision of treatment verification to the millimeter and it can be introduced as a suitable alternative for EPID in centers for increasing treatment accuracy.
Similar content being viewed by others
References
Chajon E, Castelli J, Marsiglia H (2017) The synergistic effect of radiotherapy and immunotherapy: a promising but not simple partnership. Crit Rev Oncol Hematol 111:124–132. https://doi.org/10.1016/j.critrevonc.2017.01.017
Lipsett A, Barrett S, Haruna F (2017) The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life: a systematic review and meta-analysis. Breast 32:144–155. https://doi.org/10.1016/j.breast.2017.02.002
Levitt SH, Purdy J, Perez C (2006) Technical basis of radiation therapy: practical clinical applications (medical radiology radiation oncology), 4rd edn. Springer, Berlin
Khan F, Gerbi B (2011) Treatment planning in radiation oncology Khan, 3rd edn. London, New York
Jadon R, Pembroke CA, Hanna CL et al (2014) A systematic review of organ motion and image-guided strategies in external beam radiotherapy for cervical cancer. Clin Oncol 26(4):185–196. https://doi.org/10.1016/j.clon.2013.11.031
Batumalai V, Hollowa L, Delaney G (2016) A review of setup error in supine breast radiotherapy using cone-beam computed tomography. Med Dosim 41(3):225–229. https://doi.org/10.1016/j.meddos.2016.05.001
The Institute of Physics and Engineering in Medicine and The Royal College of Radiologists (2007) On target: ensuring geometric accuracy in radiotherapy. Joint report published by the Society and College of Radiographers, London
Findlay U, Best H, Ottrey M (2016) Improving patient safety in radiotherapy through error reporting and analysis. Radiography 22(1):S3–S11. https://doi.org/10.1016/j.radi.2016.10.009
Laursen LV, Elstrøm UV, Vestergaard A et al (2012) Residual rotational set-up errors after daily cone-beam CT image guided radiotherapy of locally advanced cervical cancer. Radiother Oncol 105(2):220–225. https://doi.org/10.1016/j.radonc.2012.08.012
van der Merwe D, Van Dyk J, Healy B, Zubizarreta E, Izewska J (2016) Accuracy requirements and uncertainties in radiotherapy: a report of the International Atomic Energy Agency. 56(1):1–6
Lovik I, Anoja A, Canino S et al (2016) Verification of a port film graticule for daily quality assurance. Physica Medica 32(1):37–38. https://doi.org/10.1016/j.ejmp.2016.01.131-A-127
Morgan T, Banks D, Kagan A (1998) Radiation therapy port films: a quality assurance study. Int J Radiat Oncol Biol Phys 42(1):223–227. https://doi.org/10.1016/S0360-3016(98)00195-3
Khan F (2003) Physics of radiation therapy, 3rd edn. Minnesota
Venable K, Miles E, Hoskin P (2005) Verification films: a study of the daily and weekly reproducibility of breast patient set-up in the START trial. Clin Oncol 17(5):337–342. https://doi.org/10.1016/j.clon.2005.03.006
Hatherly K, Smylie J, Rodger A (1999) A comparison of field-only electronic portal imaging hard copies with double exposure port films in radiation therapy treatment setup validation to determine its clinical application in a radiotherapy center. Int J Radiat Oncol Biol Phys 45(3):791–796. https://doi.org/10.1016/S0360-3016(99)00249-7
Kruse J, Herman G, Hagness R et al (2002) Electronic and film portal images: a comparison of landmark visibility and review accuracy. Int J Radiat Oncol Biol Phys 54(2):584–591. https://doi.org/10.1016/S0360-3016(02)02955-3
Sun YL, Wang J (2016) Performance analysis of SIFT feature extraction algorithm in application to registration of SAR image. MATEC Web of Conferences 44:01063. https://doi.org/10.1051/matecconf/20164401063
Farman A, Sajid U, Muhammad Z et al (2016) A comparison of FAST, SURF, Eigen, Harris, and MSER Features. International Journal of Computer Engineering and Information Technology 8(6):100–105
Zhao S, Xu X, Zheng W, Jianwen L. Registration of depth image and color image based on Harris-SIFT, School of Electronic and Information Engineering, South China University of Technology, Guangzhou, China, 510641
Nakrani M, Davda R, Patel C (2014) Review: analysis of image registration techniques. International Journal of Electrical and Electronics Research 2(1):47–53
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Anjam, S., Banaee, N., Rahmani, H. et al. Determination of geometric accuracy of radiotherapy fields by port film and DRR using Matlab graphical user interface. Med Biol Eng Comput 57, 259–269 (2019). https://doi.org/10.1007/s11517-018-1852-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11517-018-1852-x