Abstract
The research focuses on leveraging convolutional neural networks (CNNs) to enhance the analysis of physiological signals, specifically photoplethysmogram (PPG) data which is a valuable tool for non-invasive heart rate prediction. Recognizing the global challenge of heart failure, the study seeks to provide a rapid, accurate, and non-invasive alternative to traditional, uncomfortable blood pressure cuffs. To achieve more accurate and efficient heart rate estimates, a k-fold CNN model with an optimal number of convolutional layers is employed. While the findings show promising results, the study addresses potential sources of error in cuffless PPG-based heart rate measurement, including motion artifacts and skin color variations, emphasizing the need for validation against gold standard methods. The research optimizes a CNN model with optimal layers, operating on 1D arrays of 8-s data slices and employing k-fold cross-validation to mitigate probabilistic uncertainties. Finally, the model yields a remarkable minimum absolute error (MAE) rate of 6.98 beats per minute (bpm), marking a significant 10% improvement over recent studies. The study also advances medical diagnostics and data analysis, then lays a strong foundation for developing cost-effective, reliable devices that offer a more comfortable and efficient way of predicting heart rate.
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References
Parati G, Ongaro G, Bilo G, Glavina F, Castiglioni P, Di Rienzo M, Mancia G (2003) Non-invasive beat-to-beat blood pressure monitoring: new developments. Blood Pressure Monitor 8(1):31–36
Yen C-T, Chang S-N, Liao C-H (2022) Estimation of beat-by-beat blood pressure and heart rate from ECG and ppg using a fine-tuned deep CNN model. IEEE Access
Chen Y, Zhang D, Karimi HR, Deng C, Yin W (2022) A new deep learning framework based on blood pressure range constraint for continuous cuffless bp estimation. Neural Netw 152:181–190
Shuzan MNI, Chowdhury MH, Hossain MS, Chowdhury ME, Reaz MBI, Uddin MM, Khandakar A, Mahbub ZB, Ali SHM (2021) A novel non-invasive estimation of respiration rate from motion corrupted photoplethysmograph signal using machine learning model. IEEE Access 9:96775–96790
Hamedani NE, Sadredini SZ, Khodabakhshi MB (2021) A CNN model for cuffless blood pressure estimation from nonlinear characteristics of PPG signals. In: 2021 28th National and 6th International Iranian Conference on Biomedical Engineering (ICBME), IEEE, pp 228–235
Yavarimanesh M, Block RC, Natarajan K, Mestha LK, Inan OT, Hahn J-O, Mukkamala R (2021) Assessment of calibration models for cuff-less blood pressure measurement after one year of aging. IEEE Trans Biomed Eng 69(6):2087–2093
Aguirregomezcorta IB, Blazek V, Leonhardt S, Antink CH (2021) Learning about reflective ppg for spo2 determination using machine learning. Current Directions Biomed Eng 7(2):33–36
Berwal D, Kuruba A, Shaikh AM, Udupa A, Baghini MS (2022) Spo2 measurement: non-idealities and ways to improve estimation accuracy in wearable pulse oximeters. IEEE Sensors J
Paliakaitė B, Charlton PH, Rapalis A, Pluščiauskaitė V, Piartli P, Kaniusas E, Marozas V (2021) Blood pressure estimation based on photoplethysmography: finger versus wrist. In: 2021 Computing in Cardiology (CinC), IEEE, vol 48, pp 1–4
Lee I, Park N, Lee H, Hwang C, Kim JH, Park S (2021) Systematic review on human skin-compatible wearable photoplethysmography sensors. Appl Sci 11(5):2313
Mena LJ, Felix VG, Ostos R, Gonzalez AJ, Martinez-Pelaez R, Melgarejo JD, Maestre GE (2020) Mobile personal healthcare system for non-invasive, pervasive and continuous blood pressure monitoring: a feasibility study. JMIR Mhealth and Uhealth
Seok D, Lee S, Kim M, Cho J, Kim C (2021) Motion artifact removal techniques for wearable EEG and PPG sensor systems. Front Electron 2:685513
Labati RD, Piuri V, Rundo F, Scotti F (2022) Photoplethysmographic biometrics: a comprehensive survey. Pattern Recognition Lett
Lin Q, Van Helleptte N (2021) Ppg sensors for the new normal: a review. In: 2021 18th International SoC Design Conference (ISOCC), IEEE, pp 276–277
Zhang G, Shin S, Jung J (2023) Cascade forest regression algorithm for non-invasive blood pressure estimation using PPG signals. Appl Soft Comput 110520
Gupta S, Singh A, Sharma A (2023) Exploiting moving slope features of PPG derivatives for estimation of mean arterial pressure. Biomed Eng Lett 13(1):1–9
Johansson A (2003) Neural network for photoplethysmographic respiratory rate monitoring. Med Biological Eng Comput 41:242–248
Jeong DU, Lim KM (2021) Combined deep CNN-LSTM network-based multitasking learning architecture for noninvasive continuous blood pressure estimation using difference in ECG-PPG features. Sci Rep 11(1):1–8
Sevinç E (2022) An empowered adaboost algorithm implementation: a COVID-19 dataset study. Comput Industrial Eng 165:107912
Sharma A, Tanwar RS, Singh Y, Sharma A, Daudra S, Singal G, Gadekallu TR, Pancholi S (2022) Heart rate and blood pressure measurement based on photoplethysmogram signal using fast Fourier transform. Comput Electrical Eng 101:108057
Salehizadeh SM, Dao D, Bolkhovsky J, Cho C, Mendelson Y, Chon KH (2015) A novel time-varying spectral filtering algorithm for reconstruction of motion artifact corrupted heart rate signals during intense physical activities using a wearable photoplethysmogram sensor. Sensors 16(1):10
Reiss A, Schmidt P, Indlekofer I, Van Laerhoven K (2018) Ppg-based heart rate estimation with time-frequency spectra: a deep learning approach. In: Proceedings of the 2018 ACM international joint conference and 2018 international symposium on pervasive and ubiquitous computing and wearable computers, pp 1283–1292
Schäck T, Muma M, Zoubir AM (2017) Computationally efficient heart rate estimation during physical exercise using photoplethysmographic signals. In: 2017 25th European signal processing conference (EUSIPCO), IEEE, pp 2478–2481
Reiss A, Indlekofer I, Schmidt P, Van Laerhoven K (2019) Deep ppg: large-scale heart rate estimation with convolutional neural networks. Sensors 19(14):3079
Moraes JL, Rocha MX, Vasconcelos GG, Vasconcelos Filho JE, De Albuquerque VHC, Alexandria AR (2018) Advances in photopletysmography signal analysis for biomedical applications. Sensors 18(6):1894
UCI machine learning repository (2022). http://archive.ics.uci.edu/ml/datasets.php
Deep PPG: Large-scale heart rate estimation with convolutional neural networks (2022). https://ubicomp.eti.uni-siegen.de/home/datasets/sensors19/
Sevinc E (2018) Activation functions in single hidden layer feed-forward neural networks. Selcuk University J Eng Sci 1–13
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Karapinar, E., Sevinc, E. A non-invasive heart rate prediction method using a convolutional approach. Med Biol Eng Comput 63, 901–914 (2025). https://doi.org/10.1007/s11517-024-03217-6
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DOI: https://doi.org/10.1007/s11517-024-03217-6