Skip to main content

Advertisement

Log in

Mining Clinical Pathways Using Dual Clustering

  • Article
  • Published:
The Review of Socionetwork Strategies Aims and scope Submit manuscript

Abstract

One of the most important tasks of data mining in a hospital is to discover structured knowledge about decision-making, which is useful for the management of clinical processes. However, most of the data in a hospital information system are stored without classification labels or the meaning of clinical actions. Thus, unsupervised learning techniques are required for analysis. This paper proposes a method which induces a clinical pathway using sample and attribute clustering of the histories of nursing orders stored in a hospital information system. The method consists of the following ve steps: first, frequencies of nursing orders are extracted from a hospital information system as a dataset in which each row and column represents nursing orders and days of the week. Second, orders are classified into several groups using sample clustering. Then, attributes clustering is applied to the data for feature selection. Fourth, for each sample and attribute clustering, the number of clusters is obtained from the sequence of the height values, and following the results of attribute clustering, the original dataset is decomposed into sub-tables. Then, the second-to-fourth steps are repeated in a recursive way until the grouping of attributes (days) are stable. Finally, a new pathway will be constructed from all the induced results. The proposed method was evaluated on datasets extracted from a hospital information system. The experiment results show that the method is useful for the construction of a clinical pathway when the distribution of length of stay is uni-modular.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

Notes

  1. Applications of ordinary statistical methods are shown in [20, 21].

References

  1. Benaglia, T., Chauveau, D., Hunter, D. R., & Young, D. (2009). mixtools: An r package for analyzing finite mixture models. Journal of Statistical Software, 32(6), 1–29.

    Article  Google Scholar 

  2. Bichindaritz, I. (2006). Memoire: A framework for semantic interoperability of case-based reasoning systems in biology and medicine. Artificial Intelligence in Medicine, 36(2), 177–192.

    Article  Google Scholar 

  3. Binti Omar, N., Supriyanto, E., Al-Ashwal, R.H., Binti Abdul Wahab, A. (2018). Personalized clinical pathway for heart failure management. In 2018 International Conference on Applied Engineering (ICAE), pp. 1–5.

  4. Cox, T., & Cox, M. (2000). Multidimensional scaling (2nd ed.). Boca Raton: Chapman & Hall/CRC.

    Book  Google Scholar 

  5. Dagliati, A., Sacchi, L., Cerra, C., Leporati, P., De Cata, P., Chiovato, L., Holmes, J.H., & Bellazzi, R. (2014) . Temporal data mining and process mining techniques to identify cardiovascular risk-associated clinical pathways in type 2 diabetes patients. In IEEE-EMBS international conference on biomedical and health informatics (BHI), pp. 240–243.

  6. Everitt, B. S., Landau, S., Leese, M., & Stahl, D. (2011). Cluster analysis (5th ed.). Hoboken: Wiley.

    Book  Google Scholar 

  7. Hanada, E., Tsumoto, S., & Kobayashi, S. (2010). A “ubiquitous environment” through wireless voice/data communication and a fully computerized hospital information system in a university hospital. In H. Takeda (ed.) E-Health, IFIP Advances in Information and Communication Technology, vol. 335, pp. 160–168. Springer, Boston.

  8. Hyde, E., & Murphy, B. (2012). Computerized clinical pathways (care plans): Piloting a strategy to enhance quality patient care. Clinical Nurse Specialist, 26(4), 277–282.

    Article  Google Scholar 

  9. Iakovidis, D., & Smailis, C. (2012). A semantic model for multimodal data mining in healthcare information systems. Studies in Health Technology and Informatics, 180, 574–578.

    Google Scholar 

  10. Igakutsushinsha (ed.). (2020). Quick Reference of DPC points (in Japanese). Igakutsushinsha, Tokyo.

  11. Iwata, H., Hirano, S., & Tsumoto, S. (2015). Maintenance and discovery of domain knowledge for nursing care using data in hospital information system. Fundamenta Informaticae, 137(2), 237–252. https://doi.org/10.3233/FI-2015-1177.

    Article  Google Scholar 

  12. Le, H.H., Edman, H., Honda, Y., Kushima, M., Yamazaki, T., Araki, K., & Yokota, H. (2017). Fast generation of clinical pathways including time intervals in sequential pattern mining on electronic medical record systems. In 2017 International Conference on Computational Science and Computational Intelligence (CSCI), pp. 1726–1731.

  13. Lee, S., & McElmurry, B. (2010). Capturing nursing care workflow disruptions: Comparison between nursing and physician workflows. Computers, Informatics, Nursing, 28(3), 151–159.

    Article  Google Scholar 

  14. Leisch, F. (2004). Flexmix: A general framework for finite mixture models and latent class regression in r. Journal of Statistical Software, 11(8), 1–18.

    Article  Google Scholar 

  15. McLachlan, G. J., & Peel, D. (2000). Finite mixture models. New York: Wiley.

    Book  Google Scholar 

  16. Mortazavi-Asl, B., Wang, J., Pinto, H., Chen, Q., & Hsu, M.C. (2004). Mining sequential patterns by pattern-growth: The prefixspan approach. IEEE Transactions on Knowledge and Data Engineering 16(11), 1424–1440 . https://doi.org/10.1109/TKDE.2004.77, http://portal.acm.org/citation.cfm?id=1024872.1025077&coll=ACM&dl=ACM [Member-Jian Pei and Senior Member-Jiawei Han and Member-Umeshwar Dayal].

  17. Rissanen, J. (2007). Information and complexity in statistical modeling. Berlin: Springer.

    Book  Google Scholar 

  18. Shortliffe, E., & Cimino, J. (Eds.). (2006). Biomedical informatics: Computer applications in health care and biomedicine (3rd ed.). Berlin: Springer.

    Google Scholar 

  19. Tsumoto, S., & Hirano, S. (2010). Risk mining in medicine: Application of data mining to medical risk management. Fundamenta Informaticae, 98(1), 107–121.

    Article  Google Scholar 

  20. Tsumoto, Y., & Tsumoto, S. (2010). Exploratory univariate analysis on the characterization of a university hospital: A preliminary step to data-mining-based hospital management using an exploratory univariate analysis of a university hospital. The Review of Socionetwork Strategies, 4(2), 47–63.

    Article  Google Scholar 

  21. Tsumoto, Y., & Tsumoto, S. (2011). Correlation and regression analysis for characterization of university hospital (submitted). The Review of Socionetwork Strategies, 5(2), 43–55.

    Article  Google Scholar 

  22. Ward, M., Vartak, S., Schwichtenberg, T., & Wakefield, D. (2011). Nurses’ perceptions of how clinical information system implementation affects workflow and patient care. Computers, Informatics, Nursing, 29(9), 502–511.

    Article  Google Scholar 

  23. WHO (1993). ICD-10. ICD-10/World Health Organization. World Health Organization.

  24. Xu, X., Jin, T., Wang, J. (2016). Summarizing patient daily activities for clinical pathway mining. In 2016 IEEE 18th international conference on e-health networking, applications and services (Healthcom), pp. 1–6

  25. Xu, X., Jin, T., Wei, Z., Lv, C., & Wang, J. (2016). Tcpm: Topic-based clinical pathway mining. In 2016 IEEE first international conference on connected health: Applications, systems and engineering technologies (CHASE), pp. 292–301.

  26. Yang, W., & Su, Q. (2014). Process mining for clinical pathway: Literature review and future directions. In 2014 11th international conference on service systems and service management (ICSSSM), pp. 1–5.

  27. Zhang, X., & Chen, S. (2012). Pathway identification via process mining for patients with multiple conditions. In 2012 IEEE international conference on industrial engineering and engineering management, pp. 1754–1758.

Download references

Acknowledgements

This research is supported by a Grant-in-Aid for Scientific Research (B) 15H2750 and 18H03289 from Japan Society for the Promotion of Science (JSPS).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shusaku Tsumoto.

Ethics declarations

Conflict of interest

On behalf of all authors, the corresponding author states that there are no conflicts of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tsumoto, S., Kimura, T. & Hirano, S. Mining Clinical Pathways Using Dual Clustering. Rev Socionetwork Strat 15, 287–307 (2021). https://doi.org/10.1007/s12626-021-00082-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12626-021-00082-9

Keywords

Navigation