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Temporal and spatial flow structures in a simulated vessel with stenotic lesion using time-resolved PIV technique

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Abstract

The stenotic geometry produces spatial and temporal regions such as high and low wall shear stress and flow separation. This disturbed blood flow in stenotic vessel can result in the further progress of atherogenesis. Therefore, the association between blood flow and geometrical factor need to be figured out by understanding the hemodynamic phenomena. The pulsatile flow features through a stenotic tube were investigated based on angiograms using a time-resolved particle image velocimetry (PIV) technique. A model of the tube core with stenosis was fabricated using a 3D printer, and the final tube model was fabricated with PDMS (polydimethylsiloxane). To prevent optical distortion, a mixture with glycerin and de-ionized water was used as the flow medium and a substitute for blood plasma. For PIV measurements, the concentration of fluorescence particles was controlled about 0.01 wt%. The flow rates were controlled using a circulating pump and silicon tubes from 1.6 to 3.7 mL/min. The pulsatile flow generates the local region of the maximum velocity at the post-stenosis and the shedding vortices move downstream over the time. The experiment indicates that such movements of vortices are quite different from the stagnant recirculation zone under the steady flow condition. With accumulating two-dimensional spatial flow fields obtained by phase averaging, the three-dimensional flow structure with the maximum velocity region was found to be a doughnut-shaped vortex ring.

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Abbreviations

θ 1, θ 2 :

Angle of incidence and refraction [°]

n :

Refractive index

ρ :

Density [kg/m3]

μ :

Viscosity [kg/m s]

D :

Diameter of channel [m]

Q :

Flow rate [m3/s]

A :

Cross-sectional area [m2]

X :

Distance for axial direction from the center of channel. The x-coordinate of the center is x = 0. [m]

r :

Distance for radial direction from the center of cross section of channel [m]

R :

Radius of channel [m]

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Acknowledgements

This work was supported by the Korea Research Foundation Grant (National Research Foundation of Korea) with funding from the Korean Government (2013R1A1A2012160 and 2016R1D1A1A02937232).

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Authors and Affiliations

  1. School of Mechanical Engineering, Pusan National University, Busan, 46241, Korea

    Hyeonji Hong, Hyun Dong Kim & Kyung Chun Kim

  2. MEMS Technology Centre, Pusan National University, Busan, 46241, Korea

    Ho Seong Ji

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  1. Hyeonji Hong
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  2. Ho Seong Ji
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  4. Kyung Chun Kim
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Correspondence to Ho Seong Ji or Kyung Chun Kim.

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Hong, H., Ji, H.S., Kim, H.D. et al. Temporal and spatial flow structures in a simulated vessel with stenotic lesion using time-resolved PIV technique. J Vis 20, 833–845 (2017). https://doi.org/10.1007/s12650-017-0432-8

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  • DOI: https://doi.org/10.1007/s12650-017-0432-8

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