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Ensemble based technique for the assessment of fetal health using cardiotocograph – a case study with standard feature reduction techniques

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Abstract

Intrauterine fetal hypoxia is one of the leading cause of perinatal mortality and morbidity. This can eventually lead to severe neurological damage like cerebral palsy and in extreme cases to fetal demise. It is thus necessary to monitor the fetus during intrapartum and antepartum period. Cardiotocograph (CTG) as a method of assessing the status of the fetus had been in use for last six decades. Nowadays it is the most widely used non-invasive technique for the continuous monitoring of the fetal heart rate (FHR) and the uterine contraction pressure (UCP). Though its introduction limited the birth related problems, the accuracy of interpretation was hindered by quite a few factors. Different guidelines that are provided for the interpretation are based on crisp logic which fails to capture the inherent uncertainty present in the medical diagnosis. Misinterpretations had led to inaccurate diagnosis which resulted in many medico-legal litigations. The vagueness present in the physician’s evaluation is best modeled using soft-computing based techniques. In this paper authors used the CTG dataset from UCI Irvine Machine Learning Data Repository which contains 2126 data and each data-point is represented by 37 features. Dimensionality of the feature set was reduced using different automated methods as well as manually by the physicians. The resulting data sets were classified using various machine learning algorithms. Aim of this study is to establish which set of features is best suited to give good insight into the status of the fetus and also determine the most effective machine learning technique for this purpose. The accuracy of the outcomes were measured using statistical methods such as sensitivity, specificity, precision, F-Measure, confusion matrix and kappa value. We obtained an accuracy of 99.91% and kappa measure of 0.997 when the feature set was reduced using MRMR.

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References

  1. Alonso-Betanzos A, Guijarro-Berdiñas B, Moret-Bonillo V, López-Gonzalez S (1995) The NST-EXPERT project: the need to evolve. J Artif Intell Med 7(4):297–313

    Article  Google Scholar 

  2. Barber DC, Howlett PJ, Smart R (1975) Principal component analysis in medical research. J Appl Stat 2(1):39–43

    Article  Google Scholar 

  3. Barquero-Pérez Ó, Santiago-Mozos R, Lillo-Castellano JM, García-Viruete B, Goya-Esteban R, Caamaño AJ, Rojo-Álvarez JL, Martín-Caballero C et al (2017) Fetal heart rate analysis for automatic detection of perinatal hypoxia using normalized compression distance and machine learning. Front Physiol 8:113. https://doi.org/10.3389/fphys.2017.00113

  4. Cömert Z, Kocamaz AF (2018) Fetal hypoxia detection based on deep convolutional neural network with transfer learning approach. Springer series on chemical sensors and biosensors 239–248.

  5. Das, S., Roy, K., Saha, C.K. (2013) Application of FURIA in the classification of cardiotocograph. In: IEEE- International Conference on Research and Development Prospects on Engineering and Technology, pp. 120–124. IEEE Press, Chennai

  6. Das S, Roy K, Saha C K (2017) A linear time series analysis of fetal heart rate to detect the variability: measures using cardiotocography. In: Bhattacharyya S, Das N, Bhattacharyya D, Mukherjee A (ed). Handbook of research on recent developments in intelligent communication application, vol. 1. IGI Global, pp 471–495.

  7. Dawes GS, Visser GH, Goodman JD, Redman CW (1981) Numerical analysis of the human fetal heart rate: the quality of ultrasound records. Am J Obstet Gynecol 141(1):43–52

    Article  Google Scholar 

  8. De-Campos A, Spong CY, Chandraharan E (2015) FIGO consensus guidelines on Intrapartum fetal monitoring. Int J Gynecol Obstet 131(1):13–24

    Article  Google Scholar 

  9. Georgoulas G, Stylios D, Groumpos P (2006) Predicting the risk of metabolic acidosis for newborns based on fetal heart rate signal classification using support vector machines. IEEE Trans Biomed Eng 53:875–884

    Article  Google Scholar 

  10. Ghodsi A (2006). Dimensionality reduction a short tutorial Department of Statistics and Actuarial Science, University of Waterloo.

  11. Giussani DA (2016) The fetal brain sparing response to hypoxia: physiological mechanisms. J Physiol 594:1215–1230

    Article  Google Scholar 

  12. Gogolewski K, Sykulski M, Chung NC, Gambin A (2019) Truncated robust principal component analysis and noise reduction for single cell RNA sequencing data. J Comput Biol. https://doi.org/10.1089/cmb.2018.0255

  13. Guijarro-Berdinas B, Alonso-Betanzos A, Fontella-Romero O (2002) Intelligent analysis and pattern recognition in cardiotocographic signals using a tightly coupled hybrid system. Elsevier. Artificial Intelligence 136(1):1–27

    Article  Google Scholar 

  14. Huang M-L, Hsu Y-Y (2012) Fetal distress prediction using discriminant analysis, decision tree, and artificial neural network. J Biomed Sci Eng 05:526–533

    Article  Google Scholar 

  15. Macones GA et al (2008) The 2008 National Institute of Child Health and Human Development workshop report on electronic fetal monitoring: update on definitions, interpretation, and research guidelines. J Am College Obstet Gynecol 112:661–666

    Google Scholar 

  16. Maeda K (2014) Fetal hypoxia. J Health Med Informat. https://doi.org/10.1891/9780826172310.0015

  17. Maeda K, Noguchi Y, Utsu M, Nagassawa K (2015) Algorithms for computerized fetal heart rate diagnosis with direct reporting. Algorithms 8(1):395–406

    Article  Google Scholar 

  18. Murotsuki J, Bocking AD, Gagnon R (1997) Fetal heart rate patterns in growth restricted fetal sheep induced by chronic fetal placental embolization. Am J Obstet Gynecol 176(2):282–290

    Article  Google Scholar 

  19. Ocak H (2013) A medical decision support system based on support vector machines and the genetic algorithm for the evaluation of fetal well-being. J Med Syst. https://doi.org/10.1007/s10916-012-9913-4

  20. Ozyilmaz L, Yildirim T (2004) ROC analysis for fetal hypoxia problem by artificial neural networks. Artificial intelligence and soft computing—ICAISC 2004, volume 3070, lecture notes in artificial intelligence. Springer, Berlin, pp 1026–1030

    MATH  Google Scholar 

  21. Peng H, Long F, Ding C (2005) Feature selection based on mutual information: criteria of max-dependency, max-relevance, and min-redundancy. IEEE Trans Pattern Anal Mach Intell 27(8):1226–1238

    Article  Google Scholar 

  22. Petrozziello A, Redman CWG, Papageorghiou AT, Jordanov I, Georgieva A (2019) Multimodal convolutional neural networks to detect fetal compromise during labor and delivery. IEEE Access 7(1):112026–112036

  23. Preti M, Chandraharan E (2018) Importance of fetal heart rate cycling during the interpretation of the cardiotocograph (CTG). International Journal of Gynecology and Reproductive Sciences 1:11–12

  24. Santo S, Ayres-de-Campos D, Santos C, Schnettler W, Ugwumadu A, Garca LMD (2017) Agreement and accuracy using the FIGO, ACOG and NICE cardiotocography interpretation guidelines. Acta Obstet Gynecol Scand 96(2):166–175

    Article  Google Scholar 

  25. UCI Irvine Data Repository (n.d.) http://archive.ics.uci.edu/ml/datasets/Cardiotocography. Accessed 05/02/2019

  26. Yilmaz E, Kilikçier C (2013) Determination of fetal state from Cardiotocogram using LSSVM with particle swarm optimization and binary decision tree. J Comput Math Methods Med 2013:1–8

    MATH  Google Scholar 

  27. Yılmaz E, Kılıkçıer Ç (2013) Determination of fetal state from Cardiotocogram using LS-SVM with particle swarm optimization and binary decision tree. Comput Math Methods Med 2013:1–8

    MATH  Google Scholar 

  28. Zhang Z, Castelló A (2017) Principal components analysis in clinical studies. Ann Transl Med 5(17):351–357

    Article  Google Scholar 

  29. Zhu M, Xia J, Yan M et al (2015) Dimensionality reduction in complex medical data: improved self-adaptive niche genetic algorithm. Comput Math Methods Med 2015:1–12

    Google Scholar 

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Correspondence to Kaushik Roy.

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Das, S., Mukherjee, H., Obaidullah, S.M. et al. Ensemble based technique for the assessment of fetal health using cardiotocograph – a case study with standard feature reduction techniques. Multimed Tools Appl 79, 35147–35168 (2020). https://doi.org/10.1007/s11042-020-08853-2

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