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Optimizing bioimpedance measurement configuration for dual-gated nuclear medicine imaging: a sensitivity study

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Abstract

Motion artefacts due to respiration and cardiac contractions may deteriorate the quality of nuclear medicine imaging leading to incorrect diagnosis and inadequate treatment. Motion artefacts can be minimized by simultaneous respiratory and cardiac gating, dual-gating. Currently, only cardiac gating is often performed. In this study, an optimized bioimpedance measurement configuration was determined for simultaneous respiratory and cardiac gating signal acquisition. The optimized configuration was located on anterolateral upper thorax based on sensitivity simulations utilizing a simplified thorax model. The validity of the optimized configuration was studied with six healthy volunteers. In the peak-to-peak and frequency content analyses the optimized configuration showed consistently higher peak-to-peak values and frequency content than other studied measurement configurations. This study indicates that the bioimpedance method has potential for the dual-gating in nuclear medicine imaging. The method would minimize the need of additional equipment, is easy for the technologists to use and comfortable for the patients.

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Acknowledgments

The authors thank MSc Ville-Pekka Seppä, Professor Jari Hyttinen and PhD Pasi Kauppinen from the Department of Biomedical Engineering, Tampere University of Technology, Finland for providing the Biopac system as well as their help for the study. PhD Mika Tarvainen from the Department of Applied Physics, University of Eastern Finland is also acknowledged for help. Moreover, the authors wish to thank all the subjects who volunteered for this study. The study was supported by the Kuopio University Hospital, Finland (EVO, project 5031345).

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Authors and Affiliations

  1. Department of Clinical Physiology and Nuclear Medicine, Diagnostic Imaging Centre, Kuopio University Hospital, P.O. Box 1777, 70211, Kuopio, Finland

    Tuomas Koivumäki, Jyrki T. Kuikka & Mikko A. Hakulinen

  2. Department of Applied Physics, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland

    Marko Vauhkonen

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  1. Tuomas Koivumäki
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  2. Marko Vauhkonen
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  3. Jyrki T. Kuikka
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Correspondence to Tuomas Koivumäki.

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Koivumäki, T., Vauhkonen, M., Kuikka, J.T. et al. Optimizing bioimpedance measurement configuration for dual-gated nuclear medicine imaging: a sensitivity study. Med Biol Eng Comput 49, 783–791 (2011). https://doi.org/10.1007/s11517-011-0787-2

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  • DOI: https://doi.org/10.1007/s11517-011-0787-2

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