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3-Tesla functional magnetic resonance imaging-guided tumor resection

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Objective We sought to determine the safety and efficacy of using 3-tesla (T) functional magnetic resonance imaging (fMRI) to guide brain tumor resection.

Material and methods From February 2004 to March 2006, fMRI was performed on 13 patients before surgical resection. Functional imaging was used to identify eloquent cortices for motor (8), speech (3), and motor and speech (2) activation using two different 3-T magnetic resonance (MR) scanners. Surgical resection was accomplished using a 1.5-T intraoperative MR system. Appropriate MR scan sequences were performed intraoperatively to determine and maximize the extent of the surgical resection.

Results Tumors included six oligodendrogliomas, three meningiomas, two astrocytomas and two glioblastomas multiforme. The fMRI data was accurate in all cases. After surgery, two patients had hemiparesis, two had worsening of their speech, and one had worsening of speech and motor function. Neurological function returned to normal in all patients within 1 month. Complete resections were possible in 10 patients (77%). Two patients had incomplete resections because of the proximity of their tumors to functional areas. Biopsy was performed in another patient with an astrocytoma in the motor strip.

Conclusion 3-T fMRI was accurate for locating neurologic function before tumor resection near eloquent cortex.

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Authors and Affiliations

  1. Departments of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN, USA

    Walter A. Hall

  2. Department of Radiation Oncology, University of Minnesota Medical School, Minneapolis, MN, USA

    Walter A. Hall

  3. Department of Radiology, University of Minnesota Medical School, Minneapolis, MN, USA

    Walter A. Hall & Charles L. Truwit

  4. MMC# 96, 420 Delaware Street SE, Minneapolis, MN, 55455, USA

    Walter A. Hall

  5. Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA

    Charles L. Truwit

  6. Department of Neurology, University of Minnesota Medical School, Minneapolis, MN, USA

    Charles L. Truwit

  7. Department of Radiology, Hennepin Country Medical Center, Minneapolis, MN, USA

    Charles L. Truwit

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  1. Walter A. Hall
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  2. Charles L. Truwit
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Correspondence to Walter A. Hall.

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Hall, W.A., Truwit, C.L. 3-Tesla functional magnetic resonance imaging-guided tumor resection. Int J CARS 1, 223–230 (2006). https://doi.org/10.1007/s11548-006-0053-5

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  • DOI: https://doi.org/10.1007/s11548-006-0053-5

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