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Marker-less intra-fraction organ motion tracking using hybrid ASM

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Aim

External beam radiation therapy attempts to deliver a high dose of ionizing radiation to destroy cancerous tissue, while sparing healthy tissues and organs at risk (OAR). Recent advances in intensity modulated radiotherapy treatment call for a greater understanding of uncertainties in the treatment process and more rigorous protocols leading to greater precision in treatment delivery. The degree to which this can be achieved depends largely on the cancer site. The treatment of organs comprises soft tissue (e.g. in the abdomen) and those subject to rhythmic movements (e.g. lungs) causing inter and intra-fraction motion artifacts that are particularly problematic. Various methods have been developed to tackle the problems caused by organ motion during radiotherapy treatment, e.g. Real-time position management respiratory gating (Varian) and synchronized moving aperture radiation therapy, developed by researchers at Harvard Medical School.

Objective

The majority of the work focuses on tracking the position of the pathologic region, with the intra-fraction shape variation of the region being largely ignored.

Materials and Methods

This paper proposes a novel method that addresses both the position and shape variation caused by the intra-fraction movement.

Conclusion

We believe this approach is able to reduce the clinical target volume margin, hence, sparing yet more of the surrounding healthy tissues from radiation exposure and limiting irradiation of OAR.

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Authors and Affiliations

  1. School of Computing Sciences, University of East Anglia, Norwich, Norfolk, NR4 7TJ, UK

    Y. Su, M. H. Fisher & R. S. Rowland

Authors
  1. Y. Su
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  2. M. H. Fisher
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  3. R. S. Rowland
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Correspondence to Y. Su.

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Su, Y., Fisher, M.H. & Rowland, R.S. Marker-less intra-fraction organ motion tracking using hybrid ASM. Int J CARS 2, 231–243 (2007). https://doi.org/10.1007/s11548-007-0133-1

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  • DOI: https://doi.org/10.1007/s11548-007-0133-1

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