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Automatic self-gated 4D-MRI construction from free-breathing 2D acquisitions applied on liver images

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

MRI slice reordering is a necessary step when three-dimensional (3D) motion of an anatomical region of interest has to be extracted from multiple two-dimensional (2D) dynamic acquisition planes, e.g., for the construction of motion models used for image-guided radiotherapy. Existing reordering methods focus on obtaining a spatially coherent reconstructed volume for each time. However, little attention has been paid to the temporal coherence of the reconstructed volumes, which is of primary importance for accurate 3D motion extraction. This paper proposes a fully automatic self-sorting four-dimensional MR volume construction method that ensures the temporal coherence of the results.

Methods

First, a pseudo-navigator signal is extracted for each 2D dynamic slice acquisition series. Then, a weighted graph is created using both spatial and motion information provided by the pseudo-navigator. The volume at a given time point is reconstructed following the shortest paths in the graph starting that time point of a reference slice chosen based on its pseudo-navigator signal.

Results

The proposed method is evaluated against two state-of-the-art slice reordering algorithms on a prospective dataset of 12 volunteers using both spatial and temporal quality metrics. The automated end-exhale extraction showed results closed to the median value of the manual operators. Furthermore, the results of the validation metrics show that the proposed method outperforms state-of-the-art methods in terms of both spatial and temporal quality.

Conclusion

Our approach is able to automatically detect the end-exhale phases within one given anatomical position and cope with irregular breathing.

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Funding

This work was partly funded by an NSERC collaborative research and development Project (CRDPJ-517413-17).

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Correspondence to Liset Vázquez Romaguera.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

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Vázquez Romaguera, L., Olofsson, N., Plantefève, R. et al. Automatic self-gated 4D-MRI construction from free-breathing 2D acquisitions applied on liver images. Int J CARS 14, 933–944 (2019). https://doi.org/10.1007/s11548-019-01941-1

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  • DOI: https://doi.org/10.1007/s11548-019-01941-1

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