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Preparation and Characterization of Zinc and Magnesium Doped Bioglasses

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Nanoscience and Nanotechnology in Security and Protection against CBRN Threats

Abstract

Peri-implantitis is an infectious disease that affects about one of five patients who receive a dental implant within 5 years after the surgery. To minimize this reaction the development of new biomaterials with antibacterial action is needed that can be used as a coating material in orthodontic implants. In addition, these biomaterials can be doped with several ions, which add specific properties that may act at the cellular level, such as increasing the angiogenesis efficiency. In this work, 45S5 Bioglass® has been used as the base material because it presents higher bioactivity compared to other biomaterials. To add antibacterial function and increase positive effects on bone metabolism, zinc and magnesium ions were introduced in the glass network. The main objective was the synthesis of the 45S5 glass by melt-quenching and study the biological performance as function of the zinc and magnesium concentrations. The structural and biological properties of the prepared samples are discussed.

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Authors and Affiliations

  1. I3N and Physics Department, University of Aveiro, Aveiro, Portugal

    Sílvia Rodrigues Gavinho, Mariana Castro Soares & Manuel Pedro Fernandes Graça

  2. I3N- CENIMAT, New University of Lisbon, Lisbon, Portugal

    João Paulo Borges & Jorge Carvalho Silva

  3. UCIBIO, REQUIMTE, Departamento Ciências da Vida, Faculdade de Ciências e Tecnologia, FCT-NOVA, Almada, Portugal

    Isabel Sá Nogueira

Authors
  1. Sílvia Rodrigues Gavinho
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  2. Mariana Castro Soares
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  3. João Paulo Borges
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  4. Jorge Carvalho Silva
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  5. Isabel Sá Nogueira
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  6. Manuel Pedro Fernandes Graça
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Corresponding author

Correspondence to Manuel Pedro Fernandes Graça .

Editor information

Editors and Affiliations

  1. Department of Physics, University of Chemical Technology & Metallurgy, Sofia, Bulgaria

    Plamen Petkov

  2. Université Ibn-Tofail, Kénitra, Morocco

    Mohammed Essaid Achour

  3. Institute of Nanostructure Technologies and Analytics, University of Kassel, Kassel, Germany

    Cyril Popov

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Gavinho, S.R., Soares, M.C., Borges, J.P., Silva, J.C., Nogueira, I.S., Graça, M.P.F. (2020). Preparation and Characterization of Zinc and Magnesium Doped Bioglasses. In: Petkov, P., Achour, M., Popov, C. (eds) Nanoscience and Nanotechnology in Security and Protection against CBRN Threats. NATO Science for Peace and Security Series B: Physics and Biophysics. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-2018-0_38

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