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A Review on Bio-functionalization of β-Ti Alloys

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Abstract

β-Ti alloys are known for their very low Young’s modulus, excellent physical properties, and biocompatibility, hence they are considered as attractive metallic materials for long-term bone implant applications. However, β-Ti alloys are poor wear resistant and typically bioinert materials, thus their surfaces need to be modified to have wear resistant and bioactive properties. In this paper, an overview is given to the available surface functionalization techniques to improve the biological properties of β-Ti alloys. Mechanical, physical, chemical, and electrochemical treatments, as well the immobilization of bio-functional molecules are discussed. Bioactivity, biocompatibility, haemocompatibility, wear and/or corrosion, behaviour of the β-Ti alloys can be improved using a proper surface modification technique, by altering the surface composition and topography or removing the undesired material from the alloy surface.

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Acknowledgements

This work was supported by FCT national funds, under the national support to R&D units grant, through the reference project UIDB/04436/2020 and UIDP/04436/2020, together with M-ERA-NET/0001/2015 project. I. Çaha is grateful for financial support through PhD grant under the NORTE-08-5369-FSE-000012 project.

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  1. CMEMS-UMinho – Center for MicroElectroMechanical Systems, Universidade do Minho, Azurém, 4800-058, Guimarães, Portugal

    I. Çaha, A. C. Alves & F. Toptan

  2. Tribocorrosion and Nanomedicine, IBTN/Br – Brazilian Branch of the Institute of Biomaterials, Bauru, SP, Brazil

    L. A. Rocha

  3. Dep. Física, Faculdade de Ciências de Bauru, UNESP—Univ. Estadual Paulista, Bauru, SP, 17033-360, Brazil

    L. A. Rocha

  4. IBTN/Euro – European Branch of the Institute of Biomaterials, Tribocorrosion and Nanomedicine, Dept. Eng. Mecânica, Universidade do Minho, Azurém, 4800-058, Guimarães, Portugal

    F. Toptan

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Çaha, I., Alves, A.C., Rocha, L.A. et al. A Review on Bio-functionalization of β-Ti Alloys. J Bio Tribo Corros 6, 135 (2020). https://doi.org/10.1007/s40735-020-00432-0

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