Abstract
We have developed a computerized method using a neural network for the segmentation of lung fields in chest radiography. The lung is the primary region of interest in routine chest radiography diagnosis. Since computer is expected to perform disease pattern search automatically, it is important to design appropriate algorithms to delineate the region of interest. A reliable segmentation method is essential to facilitate subsequent searches for image patterns associated with lung diseases. In this study, we employed a shift invariant neural network coupled with error back-propagation training method to extract the lung fields. A set of computer algorithms were also developed for smoothing the initially detected edges of lung fields. Our preliminary results indicated that 86% of the segmented lung fields globally matched the original chest radiographs. We also found that the method facilitates the development of computer algorithms in the field of computer-aided diagnosis.
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N. Nakamori, K. Doi, V. Sabeti, and H. MacMahon, “Image feature analysis and computer-aided diagnosis in digital radiography: Automated analysis of sizes of heart and lung in chest images”, Medical Physics, Vol. 17, pp. 342–350, 1990.
S. Katsuragawa, K. Doi, and H. MacMahon, “Image feature analysis and computer-aided diagnosis in digital radiography: Detection and characterization of interstitial lung diseases in digital chest radiographs”, Medical Physics, Vol. 15, pp. 311–319, 1988.
S. Katsuragawa, K. Doi, and H. MacMahon, “Image feature analysis and computer-aided diagnosis in digital radiography: Classification of normal and abnormal lung with interstitial diseases in chest images”, Medical Physics, Vol. 16, pp. 38–44, 1989.
N. Asada, K. Doi, H. MacMahon, S. Montner, M.L. Giger, C. Abe, and Y. Wu, “Neural network approach for differential diagnosis of interstitial lung diseases”, SPIE Proceedings, Medical Imaging IV: Image Processing, Vol. 1233, pp. 45–50, 1990.
G.F. Powell, K. Doi, and S. Katsuragawa, “Localization of inter-rib spaces for lung texture analysis and computer-aided diagnosis in digital chest images”, Medical Physics, Vol. 15, pp. 581–587, 1988.
K.L. Giger, K. Doi, and H. MacMahon, “Image feature analysis and computer-aided diagnosis in digital radiography: Automated detection of nodules in peripheral lung field”, Medical Physics, Vol. 15, pp. 158–166, 1988.
S.-C.B. Lo, M.T. Freedman, J.S. Lin, and S.K. Mun, “Automatic lung nodule detection using profile matching and back-propagation neural network techniques”, Journal of Digital Imaging, Vol. 6, pp. 48–54, 1993.
S.-C.B. Lo, S.L. Lou, J.S. Lin, M.T. Freedman, M.V. Chien, and S.K. Mun, “Artificial convolution neural network techniques and applications to lung nodule detection”, IEEE Trans. Med. Imag., Vol. 14, No.4, pp. 711–718, 1995.
S.-C.B. Lo, H.P. Chan, J.S. Lin, H. Li, M.T. Freedman, and S.K. Mun, “Artificial convolution neural network for medical image pattern recognition”, Neural Networks, Vol. 8, Nos.7/8, pp. 1201–1214, 1995.
J.S. Lin, S.-C.B. Lo, A. Hasegawa, M.T. Freedman, and S.K. Mun, “Reduction of false positives in lung nodule detection using a two-level neural classification”, IEEE Trans. Med. Imag., Vol. 15, No.2, pp. 216–227, 1996.
S. Sanada, K. Doi, and H. MacMahon, “Image feature analysis and computer-aided diagnosis in digital radiography: Automated detection of pneumothrox in chest images”, Medical Physics, Vol. 19, pp. 1153–1160, 1992.
A. Kano, K. Doi, H. MacMahon, D.D. Hassell, and M.L. Giger, “Digital image subtraction of temporally sequential chest images for detection of interval change”, Medical Physics, Vol. 21, pp. 453–461, 1994.
M.F. McNitt-Gray, R.K. Taira, S.E. Eldredge, and M. Razavi, “Brightness and contrast adjustments for different tissue densities for digital chest radiographs”, SPIE Proc., Vol. 1445, pp. 468–478, 1991.
M.F. McNitt-Gray, J.W. Sayre, H.K. Huang, and M. Razavi, “A pattern classification approach to segmentation of chest radiographs”, SPIE Proceedings, Medical Imaging, Vol. 1898, pp. 160–170, 1993.
J. Duryea and J.M. Boone, “A fully automated algorithm for the segmentation of lung fields on digital chest radiographic images”, Medical Physics, Vol. 22, pp. 183–191, 1995.
X.W. Xu and K. Doi, “Image feature analysis for computer-aided diagnosis: Accurate determination of ribcage boundary in chest radiographs”, Medical Physics, Vol. 22, pp. 617–626, 1995.
X.W. Xu and K. Doi, “Image feature analysis for computer-aided diagnosis: Detection of right and left hemidiaphragm edges and delineation of lung field of chest radiographs”, Medical Physics, Vol. 23, pp. 1613–1624, 1996.
M. Sonada, M. Takano, J. Miyahara, and H. Kato, “Computed radiography utilizing scanning laser stimulated luminescence”, Radiology, Vol. 148, pp. 833–838, 1983.
G. Cybenko, “Approximation by superpositions of a sigmoidal function”, Mathematics of Control, Signals, and Systems, Vol. 2, pp. 303–314, 1989.
R.M. Nishikawa, M.L. Giger, K. Doi, C.J. Vyborny, R.A. Schmidt, C.E. Metz, Y. Wu, F.F. Yin, Y. Jiang, Z. Huo, P. Lu, W. Zhang, T. Ema, U. Bick, J. Papaioannou, and R.H. Nagel, “Computer-aided detection and diagnosis of masses and clustered microcalcifications from digital mammograms”, SPIE Proceedings, Medical Imaging, Vol. 1905, pp. 422–432, 1993.
Y. Wu, K. Doi, M.L. Giger, and R.M. Nishikawa, “Computerized detection of clustered microcalcifications in digital mammograms: Application of artificial neural networks”, Medical Physics, Vol. 19, pp. 555–560, 1992.
G.D. Tourassi, C. Floyd, H.D. Sostman, and R.E. Coleman, “Acute pulmonary embolism: Artificial neural network approach for diagnosis”, Radiology, Vol. 189, pp. 555–558, 1993.
W. Zhang, K. Doi, M.L. Giger, Y. Wu, R.M. Nishikawa, and R.A. Schmidt, “Computerized detection of clustered microcalcification in digital mammograms using a shift-invariant artificial neural network”, Medical Physics, Vol. 21, pp. 517–524, 1994.
D.E. Rumelhart, G.E. Hinton, and R.J. Williams, “Learning internal representations by error propagation”, in Parallel Distributed Processing, D.E. Rumelhart and J.L. McClelland (Eds.), MIT Press, Cambridge, pp. 318–362, 1986.
K. Fukushima, S. Miyake, and T. Ito, “Neocognitron: A neural network model for a mechanism of visual pattern recognition”, IEEE Trans. on Sys., Man, and Cyber., Vol. SMC-13, pp. 826–834, 1983.
Y. LeCun, B. Boser, J.S. Denker, D. Henderson, R.E. Howard, W. Hubbard, and L.D. Jackel, “Backpropagation applied to handwritten zip code recognition”, Neural Comp., Vol. 1, pp. 541–551, 1989.
H.P. Chan, S.-C.B. Lo, B. Sahiner, K.L. Lam, and M.A. Helvie, “Computer-aided diagnosis of mammographic microcalcifications: Pattern recognition with an artificial neural network”, Medical Physics, Vol. 22, pp. 1555–1567, 1995.
Y.C. Wu, S.-C.B. Lo, M.T. Freedman, R.A. Zuurbier, A. Hasegawa, and S.K. Mun, “Classification of microcalcifications in radiographs of pathological specimen for the diagnosis of breast cancer”, Academic Radiology, Vol. 2, pp. 199–204, 1995.
W. Zhang, K. Itoh, J. Tanida, and Y. Ichioka, “Parallel distributed processing model with local space-invariant interconnections and its optical architecture”, Appl. Opt., Vol. 29, pp. 4790–4797, 1990.
E.B. Baum and D. Haussler, “What size net gives valid generalization?”, Neural Comp., Vol. 1, pp. 151–160, 1989.
W. Zhang, A. Hasegawa, K. Itoh, and Y. Ichioka, “Image processing of human corneal endothelium based on a learning network”, Appl. Opt., Vol. 30, pp. 4211–4217, 1991.
A. Hasegawa, W. Zhang, K. Itoh, and Y. Ichioka, “Neural network-based image processing on human corneal endothelial micrograms”, Proc. Soc. Photo-Opt. Instrum. Eng.,Wave Propagation and Scattering in Varied Media II, San Diego, California, Vol. 1558, pp. 414–421, 1991.
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Hasegawa, A., Lo, SC.B., Lin, JS. et al. A Shift-Invariant Neural Network for the Lung Field Segmentation in Chest Radiography. The Journal of VLSI Signal Processing-Systems for Signal, Image, and Video Technology 18, 241–250 (1998). https://doi.org/10.1023/A:1007937214367
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DOI: https://doi.org/10.1023/A:1007937214367