Abstract
We develop the theory and accompanying algorithm for the recovery of a dendritic neuron's cytoplasmic resistivity, membrane capacitance, leakage conductance, and two maximal channel conductances from weighted averages of simultaneous recordings of somatic and dendritic potential following a somatic current stimulus. We test our results on two model systems with distinct, though prescribed, channel kinetics and branching patterns.
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Cox, S.J., Griffith, B.E. Recovering Quasi-Active Properties of Dendritic Neurons from Dual Potential Recordings. J Comput Neurosci 11, 95–110 (2001). https://doi.org/10.1023/A:1012858230117
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DOI: https://doi.org/10.1023/A:1012858230117