Active shape models incorporating isolated landmarks for medical image annotation

Tobias Norajitra; Hans-Peter Meinzer; Bram Stieltjes; Klaus H. Maier-Hein

doi:10.1117/12.2043761

20 March 2014 Active shape models incorporating isolated landmarks for medical image annotation

Tobias Norajitra, Hans-Peter Meinzer, Bram Stieltjes, Klaus H. Maier-Hein

Proceedings Volume 9035, Medical Imaging 2014: Computer-Aided Diagnosis; 90353J (2014) https://doi.org/10.1117/12.2043761
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

Apart from their robustness in anatomic surface segmentation, purely surface based 3D Active Shape Models lack the ability to automatically detect and annotate non-surface key points of interest. However, annotation of anatomic landmarks is desirable, as it yields additional anatomic and functional information. Moreover, landmark detection might help to further improve accuracy during ASM segmentation. We present an extension of surface-based 3D Active Shape Models incorporating isolated non-surface landmarks. Positions of isolated and surface landmarks are modeled conjoint within a point distribution model (PDM). Isolated landmark appearance is described by a set of haar-like features, supporting local landmark detection on the PDM estimates using a kNN-Classi er. Landmark detection was evaluated in a leave-one-out cross validation on a reference dataset comprising 45 CT volumes of the human liver after shape space projection. Depending on the anatomical landmark to be detected, our experiments have shown in about 1/4 up to more than 1/2 of all test cases a signi cant improvement in detection accuracy compared to the position estimates delivered by the PDM. Our results encourage further research with regard to the combination of shape priors and machine learning for landmark detection within the Active Shape Model Framework.

Citation Download Citation

Tobias Norajitra, Hans-Peter Meinzer, Bram Stieltjes, and Klaus H. Maier-Hein "Active shape models incorporating isolated landmarks for medical image annotation", Proc. SPIE 9035, Medical Imaging 2014: Computer-Aided Diagnosis, 90353J (20 March 2014); https://doi.org/10.1117/12.2043761

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KEYWORDS

3D modeling

Liver

Statistical modeling

Image segmentation

Bladder

Data modeling

Error analysis

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