Scanning, registration, and fiber estimation of rabbit hearts using micro-focus and refraction-contrast x-ray CT

Hirohisa Oda; Holger R. Roth; Takaaki Sugino; Naoki Sunaguchi; Noriko Usami; Masahiro Oda; Daisuke Shimao; Shu Ichihara M.D.; Tetsuya Yuasa; Masami Ando; Toshiaki Akita M.D.; Yuji Narita M.D.; Kensaku Mori M.D.

doi:10.1117/12.2512145

15 March 2019 Scanning, registration, and fiber estimation of rabbit hearts using micro-focus and refraction-contrast x-ray CT

Hirohisa Oda, Holger R. Roth, Takaaki Sugino, Naoki Sunaguchi, Noriko Usami, Masahiro Oda, Daisuke Shimao, Shu Ichihara M.D., Tetsuya Yuasa, Masami Ando, Toshiaki Akita M.D., Yuji Narita M.D., Kensaku Mori M.D.

Author Affiliations +

Proceedings Volume 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging; 109531I (2019) https://doi.org/10.1117/12.2512145
Event: SPIE Medical Imaging, 2019, San Diego, California, United States

Abstract

High-resolution cardiac imaging and fiber analysis methods are desired for deeper understanding cardiac anatomy. Although refraction-contrast X-ray CT (RCT) has high contrast for soft tissues, its scanning cost is very high. On the other hand, micro-focus X-ray CT (μCT) is a modality that is commercially available with lower cost, but its contrast for soft tissue is not as high as RCT. To investigate the efficacy of μCT for fiber analysis, we scanned a common rabbit heart with both modalities with our original protocol of preparing materials, and compared their image-based analysis results. Their results were very similar, with correlation coefficient of 0.95. We confirmed that µCT volumes prepared by our protocol are useful for fiber analysis as well as RCT.

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Hirohisa Oda, Holger R. Roth, Takaaki Sugino, Naoki Sunaguchi, Noriko Usami, Masahiro Oda, Daisuke Shimao, Shu Ichihara M.D., Tetsuya Yuasa, Masami Ando, Toshiaki Akita M.D., Yuji Narita M.D., and Kensaku Mori M.D. "Scanning, registration, and fiber estimation of rabbit hearts using micro-focus and refraction-contrast x-ray CT", Proc. SPIE 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging, 109531I (15 March 2019); https://doi.org/10.1117/12.2512145

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