Method for breast cancer classification based solely on morphological descriptors

Catherine A. Todd; Golshah Naghdy

doi:10.1117/12.533938

12 May 2004 Method for breast cancer classification based solely on morphological descriptors

Catherine A. Todd, Golshah Naghdy

Proceedings Volume 5370, Medical Imaging 2004: Image Processing; (2004) https://doi.org/10.1117/12.533938
Event: Medical Imaging 2004, 2004, San Diego, California, United States

Abstract

A decision support system has been developed to assist the radiologist during mammogram classification. In this paper, mass identification and segmentation methods are discussed in brief. Fuzzy region-growing techniques are applied to effectively segment the tumour candidate from surrounding breast tissue. Boundary extraction is implemented using a unit vector rotating about the mass core. The focus of this work is on the feature extraction and classification processes. Important information relating to the malignancy of a mass may be derived from its morphological properties. Mass shape and boundary roughness are primary features used in this research to discriminate between the two types of lesions. A subset from thirteen shape descriptors is input to a binary decision tree classifier that provides a final diagnosis of tumour malignancy. Features that combine to produce the most accurate result in distinguishing between malignant and benign lesions include: spiculation index, zero crossings, boundary roughness index and area-to-perimeter ratio. Using this method, a classification result of high sensitivity and specificity is achieved, with false-positive and falsenegative rates of 9.3% and 0% respectively.

Citation Download Citation

Catherine A. Todd and Golshah Naghdy "Method for breast cancer classification based solely on morphological descriptors", Proc. SPIE 5370, Medical Imaging 2004: Image Processing, (12 May 2004); https://doi.org/10.1117/12.533938

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