Intra-operative adaptive FEM-based registration accommodating tissue resection

Petter Risholm; Eivind L. Melvær; Knut Mørken; Eigil Samset

doi:10.1117/12.811540

27 March 2009 Intra-operative adaptive FEM-based registration accommodating tissue resection

Petter Risholm, Eivind L. Melvær, Knut Mørken, Eigil Samset

Proceedings Volume 7259, Medical Imaging 2009: Image Processing; 72592Y (2009) https://doi.org/10.1117/12.811540
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Intra-operative imaging during neurosurgical procedures facilitates aggressive resections and potentially an increased surgical success rate compared to the traditional approach of relying purely on pre-operative data. However, acquisition of functional images like fMRI and DTI still have to be performed pre-operatively which necessitates registration to map them to the intra-operative image space. We present an elastic FEM-based registration algorithm which is tailored to register pre-operative to intra-operative images where a superficial tumor has been resected. To restrict matching of the cortical brain surface of the pre-operative image with the resected cavity in the intra-operative image, we define a weight function based on the "concavity" of the deformation field. These weights are applied to the load vector which effectively restricts the unwanted image forces around the resected area from matching the brain surface in the pre-operative image with the surface of the resected cavity. Another novelty of the proposed method is an adaptive multi-level FEM grid. After convergence of the algorithm on one level, the FEM grid is subdivided to add more degrees of freedom to the deformation around areas with a bad match. We present results from applying the algorithm on both 2D synthetic and medical image data and can show that the adaptivity of the grid both improves registration results and registration speed while the inclusion of the weighting function improves the results in the presence of resected tissue.

Citation Download Citation

Petter Risholm, Eivind L. Melvær, Knut Mørken, and Eigil Samset "Intra-operative adaptive FEM-based registration accommodating tissue resection", Proc. SPIE 7259, Medical Imaging 2009: Image Processing, 72592Y (27 March 2009); https://doi.org/10.1117/12.811540

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available