Application of 3D surface imaging in breast cancer radiotherapy

Tanja Alderliesten; Jan-Jakob Sonke; Anja Betgen; Joeri Honnef; Corine van Vliet-Vroegindeweij; Peter Remeijer

doi:10.1117/12.911242

16 February 2012 Application of 3D surface imaging in breast cancer radiotherapy

Tanja Alderliesten, Jan-Jakob Sonke, Anja Betgen, Joeri Honnef, Corine van Vliet-Vroegindeweij, Peter Remeijer

Proceedings Volume 8316, Medical Imaging 2012: Image-Guided Procedures, Robotic Interventions, and Modeling; 83160A (2012) https://doi.org/10.1117/12.911242
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

Purpose: Accurate dose delivery in deep-inspiration breath-hold (DIBH) radiotherapy for patients with breast cancer relies on precise treatment setup and monitoring of the depth of the breath hold. This study entailed performance evaluation of a 3D surface imaging system for image guidance in DIBH radiotherapy by comparison with cone-beam computed tomography (CBCT). Materials and Methods: Fifteen patients, treated with DIBH radiotherapy after breast-conserving surgery, were included. The performance of surface imaging was compared to the use of CBCT for setup verification. Retrospectively, breast surface registrations were performed for CBCT to planning CT as well as for a 3D surface, captured concurrently with CBCT, to planning CT. The resulting setup errors were compared with linear regression analysis. For the differences between setup errors, group mean, systematic and random errors were calculated. Furthermore, a residual error after registration (RRE) was assessed for both systems by investigating the root-mean-square distance between the planning CT surface and registered CBCT/captured surface. Results: Good correlation between setup errors was found: R²=0.82, 0.86, 0.82 in left-right, cranio-caudal and anteriorposterior direction, respectively. Systematic and random errors were ≤0.16cm and ≤0.13cm in all directions, respectively. RRE values for surface imaging and CBCT were on average 0.18 versus 0.19cm with a standard deviation of 0.10 and 0.09cm, respectively. Wilcoxon-signed-ranks testing showed that CBCT registrations resulted in higher RRE values than surface imaging registrations (p=0.003). Conclusion: This performance evaluation study shows very promising results

Citation Download Citation

Tanja Alderliesten, Jan-Jakob Sonke, Anja Betgen, Joeri Honnef, Corine van Vliet-Vroegindeweij, and Peter Remeijer "Application of 3D surface imaging in breast cancer radiotherapy", Proc. SPIE 8316, Medical Imaging 2012: Image-Guided Procedures, Robotic Interventions, and Modeling, 83160A (16 February 2012); https://doi.org/10.1117/12.911242

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available