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Health information systems, such as Computerized Provider Order Entry (CPOE), are suggested to be used as an intervention for addressing errors that arise in the medication process. Nurses are involved in all stages of the medication process; however, little is known about the impact of using CPOE on nursing practice. A grounded theory approach was employed to answer the question of “How do nurses perceive the impact of CPOE on the medication process and collaborative practice?” Ten participants were interviewed. Of the ten individuals who participated in the study, eight were observed for two hours during their work shift. The data were analyzed using a constant comparative method. The participants described using CPOE that was integrated with an electronic medication administration record (eMAR). Use of CPOE had relational, contextual, cognitive, and workflow implications. The findings of this research can be used to inform workflow modeling, CPOE design, and change management.
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