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A Concept for Mining Transitive Sequential Patterns from Pancreatic Cancer Patient Journeys
Jonas Hügel, Jan Janosch Schneider, Daniel Tran Ortega, Ella Maria Jentsch, Sophia Rheinländer, Nils Hendrik Beyer, Hossein Estiri, Christoph Ammer-Hermenau, Elisabeth Hessmann, Alexander Otto König, Volker Ellenrieder, Ulrich Sax, Clinical Research Unit 5002 (CRU 5002)
Pancreatic cancer, renowned for its aggressive nature and poor prognosis, necessitates the optimization of treatment strategies. The sequence of procedures in clinical trials is critical, such as evaluating the potential benefits of preoperative chemo-radio-therapy for pancreatic cancer. Nevertheless, we might not be aware of other temporal sequences which have an effect on therapy response or the general outcome. Extracting transitive sequential patterns from patients’ medical trajectories allows researchers to identify temporal characteristics for complex diseases. We illustrate how such sequential patterns can be discovered and might be utilized in pancreatic cancer research as well as patient care.
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