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Optimising cancer chemotherapy using an estimation of distribution algorithm and genetic algorithms

Published: 08 July 2006 Publication History

Abstract

This paper presents a methodology for using heuristic search methods to optimise cancer chemotherapy. Specifically, two evolutionary algorithms - Population Based Incremental Learning (PBIL), which is an Estimation of Distribution Algorithm (EDA), and Genetic Algorithms (GAs) have been applied to the problem of finding effective chemotherapeutic treatments. To our knowledge, EDAs have been applied to fewer real world problems compared to GAs, and the aim of the present paper is to expand the application domain of this technique.We compare and analyse the performance of both algorithms and draw a conclusion as to which approach to cancer chemotherapy optimisation is more efficient and helpful in the decision-making activity led by the oncologists.

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cover image ACM Conferences
GECCO '06: Proceedings of the 8th annual conference on Genetic and evolutionary computation
July 2006
2004 pages
ISBN:1595931864
DOI:10.1145/1143997
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Published: 08 July 2006

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Author Tags

  1. estimation of distribution algorithms
  2. evolutionary computation
  3. probabilistic modelling

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GECCO06
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GECCO06: Genetic and Evolutionary Computation Conference
July 8 - 12, 2006
Washington, Seattle, USA

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GECCO '06 Paper Acceptance Rate 205 of 446 submissions, 46%;
Overall Acceptance Rate 1,669 of 4,410 submissions, 38%

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  • (2021)Evolving Large Scale Prediction Models for Vehicle Volume Forecasting in Service StationsArtificial Intelligence XXXVIII10.1007/978-3-030-91100-3_19(224-238)Online publication date: 14-Dec-2021
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