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Genetic design automation

Published: 02 November 2009 Publication History

Abstract

Electronic design automation (EDA) tools have facilitated the design of ever more complex integrated circuits each year. Synthetic biology would also benefit from the development of genetic design automation (GDA) tools. Existing GDA tools require biologists to design genetic circuits at the molecular level, roughly equivalent to designing electronic circuits at the layout level. Analysis of these circuits is also performed at this very low level. This paper presents the background and issues involved in the development of such a GDA tool for modeling, analysis, and design.

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Cited By

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  • (2023)Synthetic Biology: Fostering the Cyber-biological RevolutionCheminformatics and Bioinformatics at the Interface with Systems Biology10.1039/9781839166037-00196(196-221)Online publication date: 8-Sep-2023
  • (2018)pySBOL: A Python Package for Genetic Design Automation and StandardizationACS Synthetic Biology10.1021/acssynbio.8b003368:7(1515-1518)Online publication date: 13-Nov-2018
  • (2016) Synthetic Biology : fostering the cyber-biological revolution Synthetic Biology10.1093/synbio/ysw0011:1(ysw001)Online publication date: 15-Jun-2016
  • Show More Cited By

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cover image ACM Conferences
ICCAD '09: Proceedings of the 2009 International Conference on Computer-Aided Design
November 2009
803 pages
ISBN:9781605588001
DOI:10.1145/1687399
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Publication History

Published: 02 November 2009

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Author Tags

  1. genetic circuits
  2. stochastic simulation
  3. synthetic biology

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Cited By

View all
  • (2023)Synthetic Biology: Fostering the Cyber-biological RevolutionCheminformatics and Bioinformatics at the Interface with Systems Biology10.1039/9781839166037-00196(196-221)Online publication date: 8-Sep-2023
  • (2018)pySBOL: A Python Package for Genetic Design Automation and StandardizationACS Synthetic Biology10.1021/acssynbio.8b003368:7(1515-1518)Online publication date: 13-Nov-2018
  • (2016) Synthetic Biology : fostering the cyber-biological revolution Synthetic Biology10.1093/synbio/ysw0011:1(ysw001)Online publication date: 15-Jun-2016
  • (2016)GeNeDA: An Open-Source Workflow for Design Automation of Gene Regulatory Networks Inspired from MicroelectronicsJournal of Computational Biology10.1089/cmb.2015.022923:10(841-855)Online publication date: Oct-2016
  • (2014)Hierarchical stochastic simulation of genetic circuitsProceedings of the Symposium on Theory of Modeling & Simulation - DEVS Integrative10.5555/2665008.2665045(1-8)Online publication date: 13-Apr-2014

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