ABSTRACT
Large number of chronic Spinal Cord Injured (SCI) patients suffer from Central Neuropathic (CNP) pain that modifies both spontaneous EEG and Event related EEG responses. The aim of this paper was to analyze on a group level, using clustering approach, differences in EEG signatures between two Groups: the able-bodied persons and SCI patients with CNP during a motor imagination task. Results of this study showed that compared to the able-bodied, SCI patients with pain have lower ERS/ERD in the central and the centro/parietal areas of the motor cortex, which correspond to the paralyzed part of the body and higher event-related synchronization/desynchronisation (ERS/ERD) in the rest of the cortex, including frontal areas, remaining areas of the sensory-motor cortex and the occipital area. Significant differences in Power Spectral Density (PSD) between two Groups were found in 20-30 Hz range, possibly related to the baseline EEG rather then to the mental task.
- Leeb R, Friedman D, Müller-Putz GR, Scherer R, Slater M, and Pfurtscheller G. 2007. Self-paced (asynchronous) BCI control of a wheelchair in virtual environments: a case study with a tetraplegic. Comput Intell Neurosci. 2007, 79642. Google ScholarDigital Library
- Kauhanen, L., Jylänki, P., Lehtonen, J., Rantanen, P., Alaranta, H., and Sams M. 2007. EEG-Based Brain-Computer Interface for Tetraplegics Comput Intell Neurosci. 2007, 23864. Google ScholarDigital Library
- Gaby G. Badr, Milos Matousek, Per K. and Frederiksen. A. 1983. Quantitative EEG Analysis of the Effects of Baclofen on Man. Neuropsychobiology 10,13--18Google ScholarCross Ref
- Salinsky MC, Binder LM, Oken BS, Storzbach D, Aron CR, Dodrill CB. Effects of Gabapentin and Carbamazepine on the EEG and Cognition in Healthy Volunteers. Epilepsia. 2002 May;43(5):482--90.Google Scholar
- Boord P, Siddall PJ, Tran Y, Herbert D, Middleton J, Craig A. 2008. Electroencephalographic slowing and reduced reactivity in neuropathic pain following spinal cord injury. Spinal Cord. 46(2).118--23Google ScholarCross Ref
- Siddall PJ, Yezierski RP, Loeser JD. 2002. Taxonomy and epidemiology of spinal cord injury pain. In: Yezierski RP, Burchiel KJ, editors. Spinal Cord Injury Pain: Assessment, Mechanisms, Management. Seattle (WI): IASP Press. p. 9--23.Google Scholar
- Hotz-Boendermaker S, Funk M, Summers P, Brugger P, Hepp-Reymond MC, Curt A, and Kollias SS. 2008. Preservation of motor programs in paraplegics as demonstrated by attempted and imagined foot movements. Neuroimage. 39(1).383--94Google ScholarCross Ref
- Delorme, A., and Makeig, S. 2004. Eeglab: an open source toolbox for analysis if single-trial EEG dynamics including independent component analysis. J. Neurosci. Methods. 134(1), 9--21.Google ScholarCross Ref
- Kavanagh, R., Darcey, T. M., Lehmann, D., and Fender, D. H. 1978. Evaluation of methods for three-dimensional localization of electric sources in the human brain. IEEE Trans Biomed Eng, 25, 421--429.Google ScholarCross Ref
- Makeig S. 1993. Auditory Event-Related Dynamics of the EEG Spectrum and Effects of Exposure to Tones. Electroencephalography and Clinical Neurophysiology 86:283--293.Google ScholarCross Ref
- Wrigley PJ, Press SR, Gustin SM, Macefield VG, Gandevia SC, Cousins MJ, Middleton JW, Henderson LA, and Siddall PJ. 2009. Neuropathic pain and primary somatosensory cortex reorganization following spinal cord injury. Pain. 141(1-2),52--9.Google ScholarCross Ref
Index Terms
- Motor imagery in spinal cord injury with neuropathic pain: a component clustering method
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