Abstract
Synthetic biologists may be closing in on potentially world-changing breakthroughs, but they are often hamstrung by a shortage of software tools.
- Amir, Y., Ben-Ishay, E., Levner, D., Ittah, S., Abu-Horowitz, A., Bachelet, I. Universal Computing by DNA origami robots in a living animal. Nature Nanotechnology. 9, 353-357 (2014). doi:10.1038/nnano.2014.58.Google ScholarCross Ref
- Douglas, S.M., Bachelet, I., Church, G.M. A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads. Science 335:831-4 (2012).Google ScholarCross Ref
- Mutalik, V., Guimaraes, J., Cambray, G., Lam, C., Christoffersen, M.J, Mai, Q., Tran, A.B., Paull, M., Keaslking, J.D., Arkin, A.P., Endy, D. Precise and reliable gene expression via standard transcription and translation initiation elements. Nature Methods. 10: 354-360 (2013). doi:10.1038/nmeth.2404Google ScholarCross Ref
- Sissel, J., Iacovelli, F., Falconi, M., Kragh, S., Christensen, B., Frøhlich, R., Franch, O., Kristoffersen, E., Stougaard, M., Leong, K.W., Ho, Y., Sørensen, E.S., Birkedal, V., Desideri, A., Knudsen, B.R. Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage, ACS Nano, 2013, DOI: 10.1021/nn4030543.Google Scholar
Index Terms
- Molecular moonshots
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