Tzu-Chueh Wang
ABSTRACT
Aging increases the danger of adverse reactions to medication, which can lead to hospitalization and mortality. Aging is also associated with increased rates of polypharmacy, which can lead to harmful interactive effects. The introduction of personalized pharmaceutical counseling for elderly patients when medications are prescribed can potentially reduce the danger of adverse reactions to medications, and thus promote public health. This paper reports on an exploratory project in elderly pharmaceutical counseling conducted in Taiwan from 2010 to 2012. An experiment group consisting of 40 patients received home pharmaceutical counseling from hospital pharmacists and community pharmacists, while a control group received only routine counseling at the time their medications were dispensed. The two groups' prescriptions were analyzed according to Beer's Criteria for Potentially Inappropriate Use of Medication. It was found that the rate of prescription of potentially inappropriate medications was reduced after home pharmaceutical counseling, when considered in terms of gender, rate of polypharmacy and age group. However, while home counseling appeared to reduce the incidence of prescription of potentially inappropriate medications at hospitals, this was not the case for community clinics. The paper discusses implications of these findings for future research and pharmaceutical practice.
- WHO. Ageing and Health Technical Report. 2004.Google Scholar
- Björkman, I. K., Fastbom, J., Schmidt, I. K., Bernsten, C. B., Caramona, M., Crealey, G., Frøkjær, B., Grünberger, E., Gustafsson, T. and Henman, M. Drug-Drug Interactions in the Elderly. Ann. Pharmacother., 36, 11 (2002), 1675--1681. Google ScholarCross Ref
- Lau, D. T., Kasper, J. D., Potter, D., Lyles, A. and Bennett, R. G. Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. Arch. Intern. Med., 165, 1 (2005), 68--74. Google ScholarCross Ref
- Lin, H.-Y., Liao, C.-C., Cheng, S.-H., Wang, P.-C. and Hsueh, Y.-S. Association of potentially inappropriate medication use with adverse outcomes in ambulatory elderly patients with chronic diseases. Drugs Aging, 25, 1 (2008), 49--59. Google ScholarCross Ref
- Nixdorff, N., Hustey, F. M., Brady, A. K., Vaji, K., Leonard, M. and Messinger-Rapport, B. J. Potentially inappropriate medications and adverse drug effects in elders in the ED. The American journal of emergency medicine, 26, 6 (2008), 697--700. Google ScholarCross Ref
- Rothberg, M. B., Pekow, P. S., Liu, F., Korc-Grodzicki, B., Brennan, M. J., Bellantonio, S., Heelon, M. and Lindenauer, P. K. Potentially inappropriate medication use in hospitalized elders. J. Hosp. Med., 3, 2 (2008), 91--102. Google ScholarCross Ref
- Fialová, D., Topinková, E., Gambassi, G., Finne-Soveri, H., Jónsson, P. V., Carpenter, I., Schroll, M., Onder, G., Sørbye, L. W. and Wagner, C. Potentially inappropriate medication use among elderly home care patients in Europe. JAMA, 293, 11 (2005), 1348--1358. Google ScholarCross Ref
- Johnell, K., Fastbom, J., Rosén, M. and Leimanis, A. Inappropriate drug use in the elderly: a nationwide register-based study. Ann. Pharmacother., 41, 7-8 (2007), 1243--1248.Google ScholarCross Ref
- Blalock, S. J., Byrd, J. E., Hansen, R. A., Yamanis, T. J., McMullin, K., DeVellis, B. M., DeVellis, R. F., Panter, A., Kawata, A. K. and Watson, L. C. Factors associated with potentially inappropriate drug utilization in a sample of rural community-dwelling older adults. The American journal of geriatric pharmacotherapy, 3, 3 (2005), 168--179. Google ScholarCross Ref
- Lechevallier-Michel, N., Gautier-Bertrand, M., Alpérovitch, A., Berr, C., Belmin, J., Legrain, S., Saint-Jean, O., Tavernier, B., Dartigues, J.-F. and Fourrier-Réglat, A. Frequency and risk factors of potentially inappropriate medication use in a community-dwelling elderly population: results from the 3C Study. Eur. J. Clin. Pharmacol., 60, 11 (2005), 813--819. Google ScholarCross Ref
- Gallagher, P. F., Barry, P. J., Ryan, C., Hartigan, I. and O'Mahony, D. Inappropriate prescribing in an acutely ill population of elderly patients as determined by Beers' Criteria. Age Ageing, 37, 1 (2008), 96--101. Google ScholarCross Ref
- Steinman, M. A., Seth Landefeld, C., Rosenthal, G. E., Berthenthal, D., Sen, S. and Kaboli, P. J. Polypharmacy and prescribing quality in older people. J. Am. Geriatr. Soc., 54, 10 (2006), 1516--1523. Google ScholarCross Ref
- Kaur, S., Mitchell, G., Vitetta, L. and Roberts, M. S. Interventions that can reduce inappropriate prescribing in the elderly. Drugs Aging, 26, 12 (2009), 1013--1028. Google ScholarCross Ref
- Chan, M., Nicklason, F. and Vial, J. Adverse drug events as a cause of hospital admission in the elderly. Intern. Med. J., 31, 4 (2001), 199--205. Google ScholarCross Ref
- Tamura, B. K., Bell, C. L., Lubimir, K., Iwasaki, W. N., Ziegler, L. A. and Masaki, K. H. Physician intervention for medication reduction in a nursing home: The polypharmacy outcomes project. J. Am. Med. Dir. Assoc., 12, 5 (2011), 326--330. Google ScholarCross Ref
- Jyrkkä, J., Enlund, H., Lavikainen, P., Sulkava, R. and Hartikainen, S. Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three-year period in an elderly population. Pharmacoepidemiol. Drug Saf., 20, 5 (2011), 514--52 Google ScholarCross Ref
Index Terms
- The Effects of Home Pharmaceutical Counseling on Prescription of Potentially Inappropriate Medications
Recommendations
Potentially Inappropriate Medication Prescription in Elderly Outpatients
ICMHI '17: Proceedings of the 1st International Conference on Medical and Health Informatics 2017Potentially inappropriate medication (PIM) is defined as medication which may result in higher than expected risk when used by elderly patients. Its risk of occurrence may be increased through the effects of drug interactions, adverse drug reactions (...
Discovering prescription patterns in pediatric acute-onset neuropsychiatric syndrome patients
Graphical abstractDisplay Omitted
Highlights- PANS has an inflammatory or autoimmune etiology associated with an infection.
- ...
Abstract ObjectivePediatric acute-onset neuropsychiatric syndrome (PANS) is a complex neuropsychiatric syndrome characterized by an abrupt onset of obsessive-compulsive symptoms and/or severe eating restrictions, along with at least ...
Development and exploration of polymedication network from Pharmaceutical and Medicare Benefits Scheme data
ACSW '19: Proceedings of the Australasian Computer Science Week MulticonferencePolypharmacy or concurrent intake of multiple medications is often associated with negative health outcomes and adverse drug reactions. Routinely collected administrative health data can be a potential and inexpensive alternative to study large ...
Comments