ABSTRACT
In the magnetic nanoparticles hyperthermia, the temperature real-time feedback is the key factor for thermal therapy to treat cancer. But the measuring accuracy of harmonic amplitude determines the accuracy of temperature. At present, the traditional method for harmonic amplitude detection, there is low precision, time-consuming and other issues, seriously affect the magnetic nanoparticles hyperthermia in the medical field of application and promotion. In order to overcome the difficulty, this paper proposes a method to extract the amplitude of harmonic signals using the digital average orthogonal algorithm. The above method describes the principle of amplitude measurement of digital averaging orthogonal algorithm, and deeply studies its detection and filtering characteristics. With the operation of filtering the harmonic components, the magnetization of the magnetic nanoparticles was simulated in the temperature range of 310K to 325K. The simulation results show that the amplitude measurement value is compared with the theoretical value, which has higher amplitude measurement accuracy and faster convergence speed.
- Takamatsu S, Matsui O, Gabata T, et al. Selective induction hyperthermia following transcatheter arterial embolization with a mixture of nano-sized magnetic particles (ferucarbotran) and embolic materials: feasibility study in rabbits[J]. Radiation medicine, 2008, 26(4): 179.Google Scholar
- Berry S L, Walker K, Hoskins C, et al. Nanoparticle-mediated magnetic hyperthermia is an effective method for killing the human-infective protozoan parasite Leishmania mexicana in vitro[J]. Scientific reports, 2019, 9(1): 1059.Google ScholarCross Ref
- Mameli V, Musinu A, Ardu A, et al. Studying the effect of Zn-substitution on the magnetic and hyperthermic properties of cobalt ferrite nanoparticles[J]. Nanoscale, 2016, 8(19): 10124--10137.Google ScholarCross Ref
- Zhong J, Liu W, Jiang L, et al. Real-time magnetic nanothermometry: The use of magnetization of magnetic nanoparticles assessed under low frequency triangle-wave magnetic fields[J]. Review of Scientific Instruments, 2014, 85(9): 094905.Google ScholarCross Ref
- Périgo E A, Hemery G, Sandre O, et al. Fundamentals and advances in magnetic hyperthermia[J]. Applied Physics Reviews, 2015, 2(4): 041302.Google ScholarCross Ref
- Kozissnik B, Bohorquez A C, Dobson J, et al. Magnetic fluid hyperthermia: advances, challenges, and opportunity[J]. International Journal of Hyperthermia, 2013, 29(8): 706--714.Google ScholarCross Ref
- Evans B A, Bausch M D, Sienerth K D, et al. Non-monotonicity in the influence of nanoparticle concentration on SAR in magnetic nanoparticle hyperthermia[J]. Journal of Magnetism and Magnetic Materials, 2018, 465: 559--565.Google ScholarCross Ref
- Wang B, Chan K F, Yu J, et al. Reconfigurable swarms of ferromagnetic colloids for enhanced local hyperthermia[J]. Advanced Functional Materials, 2018, 28(25): 1705701.Google ScholarCross Ref
- Markov D E, Boeve H, Gleich B, et al. Human erythrocytes as nanoparticle carriers for magnetic particle imaging[J]. Physics in Medicine & Biology, 2010, 55(21): 6461.Google ScholarCross Ref
- Gleich B, Weizenecker J. Tomographic imaging using the nonlinear response of magnetic particles[J]. Nature, 2005, 435(7046): 1214.Google ScholarCross Ref
- Du Z, Sun Y, Liu J, et al. Design of a temperature measurement and feedback control system based on an improved magnetic nanoparticle thermometer[J]. Measurement Science and Technology, 2018, 29(4): 045003.Google ScholarCross Ref
- Du Z, Sun Y, Su R, et al. The phosphor temperature measurement of white light-emitting diodes based on magnetic nanoparticle thermometer[J]. Review of Scientific Instruments, 2018, 89(9): 094901.Google ScholarCross Ref
- Liu W, Zhong J, Jiang L, et al. METHOD FOR MEASURING MAGNETIC NANOMETER TEMPERATURE IN TRIANGULAR WAVE EXCITATION FIELD[P]. WO 2015081585 A1. 2015-06-11.Google Scholar
- Xie J, Liu G, Eden H S, et al. Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy[J]. Accounts of chemical research, 2011, 44(10): 883--892.Google Scholar
- Jaganathan H, Ivanisevic A. Gold--iron oxide nanoparticle chains scaffolded on DNA as potential magnetic resonance imaging agents[J]. Journal of Materials Chemistry, 2011, 21(4): 939--943.Google ScholarCross Ref
- Zhu H, Demachi K, Sekino M. Phase gradient imaging for positive contrast generation to superparamagnetic iron oxide nanoparticle-labeled targets in magnetic resonance imaging[J]. Magnetic resonance imaging, 2011, 29(7): 891--898.Google Scholar
- Demas V, Lowery T J. Magnetic resonance for in vitro medical diagnostics: superparamagnetic nanoparticle-based magnetic relaxation switches[J]. New Journal of Physics, 2011, 13(2): 025005.Google ScholarCross Ref
- Du Z, Su R, Liu W, et al. Magnetic nanoparticle thermometer: An investigation of minimum error transmission path and AC bias error[J]. Sensors, 2015, 15(4): 8624--8641.Google ScholarCross Ref
- Du Z, Su R, Wei K, et al. Design and use of a very stable magnetic nanothermometer[J]. Measurement Science and Technology, 2016, 27(4): 045901.Google ScholarCross Ref
- Vainio O. Minimum-phase FIR filters for delay-constrained noise reduction[J]. IEEE Transactions on Instrumentation and Measurement, 1999, 48(6): 1100--1102.Google ScholarCross Ref
Index Terms
- Research on Harmonic Detection Algorithm Based on Magnetic Nanoparticles
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