Osama Makhamrah
ABSTRACT
This study aims at developing a reusable, multimodal liver phantom, which applies functional vasculature and displays some pathologies, such as Hepatocellular Carcinoma (HCC). This phantom can be used with different modalities, such as Ultrasonography (US), Computed Tomography (CT), and Magnetic Resonance Imaging (MRI).
The current phantom consisted of different types of mimicked tissue; liver parenchyma; HCC and major input and output vessels. They are made of different ingredients; 4% weight of gelatin powder; 2.6% weight of hydroxyethylcellulose; 0.2 weight % of benzalkonium chloride; 3.2% weight of propanediol; and 90% weight of water as a volume spreader. The selected materials mimicked liver tissue under MRI, CT and US.
The phantom preparation is simple, low cost, reusable, and takes about 24 hours for preparation. Additionally, comparison of ultrasound images, CT, and MRI of real patient's liver, the phantom's liver tissue with HCC and its structures are well simulated.
Using different steps to cast procedures, the researchers fabricated a multimodal liver phantom, with dynamic vascular channels, and models with different sized pathologies, which give a best procedure for training in different modalities. This technique can be applied to any organ in the body.
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Index Terms
- Evaluation of Liver Phantom for Testing of the Detectability Multimodal for Hepatocellular Carcinoma
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