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Privacy-preserving With Sonification For Training of Convolutional Deep Neural Networks for Melanoma Diagnosis

Published: 21 March 2021 Publication History

Abstract

Melanoma is a form of cancer that is a primary cause of skin cancer deaths. A major predictive factor for positive patient outcomes is diagnosis of disease in earlier cancer stages before the disease has spread beyond the initial lesion. However, many patients are diagnosed late because they cannot afford to meet a doctor or are embarrassed to be examined. These patients suffer from a significantly greater rate of mortality. As a remedy, machine learning models have been proposed to enable easy and automated diagnosis using images. However, the development of models for use in a clinical setting is not yet possible due to the limited availability of training data. Training data that is available is often private and thus isolated within individual institutions. Therefore, a large data set containing patients of different ancestries, skin colors, and ages is not available. In this study, we show that the Sonification of images results in a greater proportion of patients' consent to share their data in a public database, and that models trained from Sonified images have similar performance to those trained on raw skin lesion images.

References

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National Cancer Institute. SEER Cancer Stat Facts: Melanoma of the Skin. https://seer.cancer.gov/statfacts/html/melan.html. Accessed: 2020-09-30.
[2]
David C. Whiteman, Adele C. Green, and Catherine M. Olsen. "The Growing Burden of Invasive Melanoma: Projections of Incidence Rates and Numbers of New Cases in Six Susceptible Populations through 2031". In: Journal of Investigative Dermatology 136.6 (June 2016), pp. 1161--1171. URL: https://doi.org/10.1016/j.jid.2016.01.035.
[3]
Rachael Miller et al. "Epidemiology and survival outcomes in stages II and III cutaneous melanoma: a systematic review". In: Melanoma Management 7.1 (May 2020), pp. 39--53. URL: https://doi.org/10.2217/mmt-2019-0022.
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Marcus H.S.B. Xavier et al. "Delay in cutaneous melanoma diagnosis". In: Medicine 95.31 (Aug. 2016), e4396. URL: https://doi.org/10.1097/md.0000000000004396.
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Carlos A. Reyes-Ortiz et al. "Socioeconomic Status and Survival in Older Patients with Melanoma". In: Journal of the American Geriatrics Society 54.11 (Nov. 2006), pp. 1758--1764. URL: https://doi.org/10.1111/j.1532-5415.2006.00943.x.
[6]
Michael Phillips et al. "Detection of Malignant Melanoma Using Artificial Intelligence: An Observational Study of Diagnostic Accuracy". In: Dermatology Practical & Conceptual (Dec. 2019), e2020011. URL: https://doi.org/10.5826/dpc.1001a11.
[7]
B.N. Walker et al. "Dermoscopy diagnosis of cancerous lesions utilizing dual deep learning algorithms via visual and audio (sonification) outputs: Laboratory and prospective observational studies". In: EBioMedicine 40 (Feb. 2019), pp. 176--183. URL: https://doi.org/10.1016/j.ebiom.2019.01.028.
[8]
Rajeev Krishna, Kelly Kelleher, and Eric Stahlberg. "Patient Confidentiality in the Research Use of Clinical Medical Databases". In: American Journal of Public Health 97.4 (Apr. 2007), pp. 654--658. URL: https://doi.org/10.2105/ajph.2006.090902.

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  1. Privacy-preserving With Sonification For Training of Convolutional Deep Neural Networks for Melanoma Diagnosis

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    BIC '21: Proceedings of the 2021 International Conference on Bioinformatics and Intelligent Computing
    January 2021
    445 pages
    ISBN:9781450390002
    DOI:10.1145/3448748
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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    • University of Arizona: University of Arizona

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    New York, NY, United States

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    Published: 21 March 2021

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    Author Tags

    1. Convolutional Neural Network
    2. Melanoma
    3. Privacy
    4. Skin-Cancer
    5. Sonification

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