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A Systematic Literature Review of Virtual, Augmented, and Mixed Reality Game Applications in Healthcare

Authors:

Veronica SundstedtAuthors Info & Claims

ACM Transactions on Computing for Healthcare (HEALTH), Volume 3, Issue 2

Article No.: 22, Pages 1 - 27

https://doi.org/10.1145/3472303

Published: 03 March 2022 Publication History

Abstract

Virtual reality, augmented reality, and mixed reality (VR/AR/MR) as information and communication technologies have been recognised and implemented in healthcare in recent years. One of the popular application ways is games, due to the potential benefits of providing an engaging and immersive experience in a virtual environment. This study presents a systematic literature review that evaluates the state-of-the-art on VR/AR/MR game applications in healthcare by collecting and analysing related journal and conference papers published from 2014 through to the first half of 2020. After retrieving more than 3,000 papers from six databases, 88 articles, from both computer science and medicine, were selected and analysed in the review. The articles are classified and summarised based on their (1) publication information, (2) design, implementation, and evaluation, and (3) application. The presented review is beneficial for both researchers and developers interested in exploring current research and future trends in VR/AR/MR in healthcare.

References

[1]

Bilal Ahmed, Dae Hwan Kim, Yongwon Hwang, and Sung-Jun Park. 2018. Treatment of Alzheimer’s, cognitive, chronic pain rehabilitation, depression and anxiety disorders in one system for elderly using VR. In Proceedings of the 15th International Conference on Ubiquitous Robots (UR’18). IEEE, 483–488.

[2]

Emin Aksoy. 2019. Comparing the effects on learning outcomes of tablet-based and virtual reality–based serious gaming modules for basic life support training: Randomized trial. JMIR Serious Games 7, 2 (2019), e13442.

[3]

Mehmet Emin Aksoy, Kurtulus Izzetoglu, Engin Baysoy, Atahan Agrali, Dilek Kitapcioglu, and Banu Onaral. 2019. Performance monitoring via functional near infrared spectroscopy for virtual reality based basic life support training. Front. Neurosci. 13 (2019), 1336. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920174/.

[4]

Amal Alazba, Hend Al-Khalifa, and Hana AlSobayel. 2018. A proposed game for promoting physical activities among people with low back pain using virtual reality. In Proceedings of the 11th Pervasive Technologies Related to Assistive Environments Conference. ACM, 141–144.

Digital Library

[5]

Beatrice Aruanno and Franca Garzotto. 2019. MemHolo: Mixed reality experiences for subjects with Alzheimer’s disease. Multimedia Tools Appl. 78, 10 (2019), 13517–13537.

Digital Library

[6]

Ronald Azuma, Yohan Baillot, Reinhold Behringer, Steven Feiner, Simon Julier, and Blair MacIntyre. 2001. Recent advances in augmented reality. IEEE Comput. Graph. Appl. 21, 6 (2001), 34–47.

Digital Library

[7]

Oliver Baus and Stéphane Bouchard. 2014. Moving from virtual reality exposure-based therapy to augmented reality exposure-based therapy: A review. Front. Hum. Neurosci. 8 (2014), 112.

[8]

Costas Boletsis and Simon Mccallum. 2014. Augmented reality cube game for cognitive training: An interaction study. Stud. Health Technol. Inf. 200 (2014), 81–87.

[9]

Rineke Bossenbroek, Aniek Wols, Joanneke Weerdmeester, Anna Lichtwarck-Aschoff, Isabela Granic, and Marieke M. J. W. van Rooij. 2020. Efficacy of a virtual reality biofeedback game (DEEP) to reduce anxiety and disruptive classroom behavior: Single-case study. JMIR Ment. Health 7, 3 (2020), e16066.

[10]

Cristina Botella, Javier Fernández-Álvarez, Verónica Guillén, Azucena García-Palacios, and Rosa Baños. 2017. Recent progress in virtual reality exposure therapy for phobias: A systematic review. Curr. Psychiatr. Rep. 19, 7 (2017), 42.

[11]

Aikaterini Bourazeri, Tyrone Bellamy-Wood, and Sylvester Arnab. 2017. EnCity: A serious game for empowering young people with Down’s syndrome. In Proceedings of the IEEE 5th International Conference on Serious Games and Applications for Health (SeGAH’17). IEEE, 1–6.

[12]

Igor Saraiva Brasil, Francisco Milton Mendes Neto, Jose Ferdinandy Silva Chagas, Rodrigo Monteiro, Daniel Faustino Lacerda Souza, Mara Franklin Bonates, and Andre Dantas. 2011. An intelligent and persistent browser-based game for oil drilling operators training. In Proceedings of the IEEE 1st International Conference on Serious Games and Applications for Health (SeGAH’11). IEEE, 1–9.

[13]

Ion-Alexandru Bratosin, Ionel-Bujorel Păvăloiu, Andrei Vasilăeanu, Diana Gavajuc, and Nicolae Goga. 2019. Angling in virtual reality for pain relief. In Proceedings of the E-Health and Bioengineering Conference (EHB’19). IEEE, 1–4.

[14]

Benjamin Byl, Matthias Süncksen, and Michael Teistler. 2018. A serious virtual reality game to train spatial cognition for medical ultrasound imaging. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–4.

[15]

Giuseppe Caggianese, Andrea Chirico, Giuseppe De Pietro, Luigi Gallo, Antonio Giordano, Marco Predazzi, and Pietro Neroni. 2018. Towards a virtual reality cognitive training system for mild cognitive impairment and Alzheimer’s disease patients. In Proceedings of the 32nd International Conference on Advanced Information Networking and Applications Workshops (WAINA’18). IEEE, 663–667.

[16]

Andrés-Marcelo Calle-Bustos, M.-C. Juan, Inmaculada García-García, and Francisco Abad. 2017. An augmented reality game to support therapeutic education for children with diabetes. PloS One 12, 9 (2017), e0184645.

[17]

Francesco Carrino, Omar Abou Khaled, and Elena Mugellini. 2018. IMPACT. In Proceedings of the International Conference on Augmented Reality, Virtual Reality and Computer Graphics. Springer, 192–200.

[18]

Marina A. Cidota, Paulina J. M. Bank, and Stephan G. Lukosch. 2019. Design recommendations for augmented reality games for objective assessment of upper extremity motor dysfunction. In Proceedings of the IEEE Conference on Virtual Reality and 3D User Interfaces (VR’19). IEEE, 1430–1438.

[19]

Pietro Cipresso, Irene Alice Chicchi Giglioli, Mariano Alcañiz Raya, and Giuseppe Riva. 2018. The past, present, and future of virtual and augmented reality research: A network and cluster analysis of the literature. Front. Psychol. 9 (2018), 2086.

[20]

Sasha Crawford-Holland. 2019. Virtual healing: Militarizing the psyche in virtual reality exposure therapy. Televis. New Media 20, 1 (2019), 56–71.

[21]

Anuja Darekar, Bradford J. McFadyen, Anouk Lamontagne, and Joyce Fung. 2015. Efficacy of virtual reality-based intervention on balance and mobility disorders post-stroke: A scoping review. J. Neuroeng. Rehabil. 12, 1 (2015), 46.

[22]

Rodrigo Monteiro de Lima, Araken de Medeiros Santos, Francisco Milton Mendes Neto, Ademar França de Sousa Neto, Felipe César Pinheiro Leão, Francisco Tailânio de Macedo, and Anne Magaly de Paula Canuto. 2016. A 3D serious game for medical students training in clinical cases. In Proceedings of the IEEE International Conference on Serious Games and Applications for Health (SeGAH’16). IEEE, 1–9.

[23]

Małgorzata Dębska, Jacek Polechoński, Arkadiusz Mynarski, and Piotr Polechoński. 2019. Enjoyment and intensity of physical activity in immersive virtual reality performed on innovative training devices in compliance with recommendations for health. Int. J. Environ. Res. Publ. Health 16, 19 (2019), 3673.

[24]

Sebastian Deterding. 2012. Gamification: Designing for motivation. Interactions 19, 4 (2012), 14–17.

Digital Library

[25]

Sebastian Deterding, Dan Dixon, Rilla Khaled, and Lennart Nacke. 2011. From game design elements to gamefulness: Defining gamification. In Proceedings of the 15th International Academic MindTrek Conference: Envisioning Future Media Environments. ACM, 9–15.

Digital Library

[26]

Darpan Dhawan, Michael Barlow, and Erandi Lakshika. 2019. Prosthetic rehabilitation training in virtual reality. In Proceedings of the IEEE 7th International Conference on Serious Games and Applications for Health (SeGAH’19). IEEE, 1–8.

[27]

AdriáN DomíNguez, Joseba Saenz-De-Navarrete, Luis De-Marcos, Luis FernáNdez-Sanz, Carmen PagéS, and José-Javier MartíNez-HerráIz. 2013. Gamifying learning experiences: Practical implications and outcomes. Comput. Educ. 63 (2013), 380–392. https://www.sciencedirect.com/science/article/abs/pii/S0360131513000031.

Digital Library

[28]

Amy Dunn, Jeremy Patterson, Charmaine F. Biega, Alice Grishchenko, John Luna, Joseph R. Stanek, and Robert Strouse. 2019. A novel clinician-orchestrated virtual reality platform for distraction during pediatric intravenous procedures in children with hemophilia: Randomized controlled trial. JMIR Serious Games 7, 1 (2019), e10902.

[29]

Adriana de Souza e Silva and Daniel M. Sutko. 2009. Digital Cityscapes: Merging Digital and Urban Playspaces. Vol. 57. Peter Lang.

[30]

Adrien Ecrepont, Corentin Haidon, Benoit Girard, and Bob-Antoine J. Menelas. 2016. A fully customizable truck-driving simulator for the care of people suffering from Post-Traumatic Stress Disorder. In Proceedings of the IEEE International Conference on Serious Games and Applications for Health (SeGAH’16). IEEE, 1–8.

[31]

Mazhar Eisapour, Shi Cao, and Jennifer Boger. 2020. Participatory design and evaluation of virtual reality games to promote engagement in physical activity for people living with dementia. J. Rehabil. Assist. Technol. Eng. 7 (2020), 2055668320913770.

[32]

Boris Feodoroff, Ippokratis Konstantinidis, and Ingo Froböse. 2019. Effects of full body exergaming in virtual reality on cardiovascular and muscular parameters: Cross-sectional experiment. JMIR Serious Games 7, 3 (2019), e12324.

[33]

Daniel Freeman, Sarah Reeve, A. Robinson, Anke Ehlers, David Clark, Bernhard Spanlang, and Mel Slater. 2017. Virtual reality in the assessment, understanding, and treatment of mental health disorders. Psychol. Med. 47, 14 (2017), 2393–2400.

[34]

Anthony G. Gallagher, E. Matt Ritter, Howard Champion, Gerald Higgins, Marvin P. Fried, Gerald Moses, C. Daniel Smith, and Richard M. Satava. 2005. Virtual reality simulation for the operating room: Proficiency-based training as a paradigm shift in surgical skills training. Ann. Surg. 241, 2 (2005), 364.

[35]

Sonja Schmer Galunder, Jeremy F. Gottlieb, Jack Ladwig, Josh Hamell, Peter K. Keller, and Peggy Wu. 2018. A VR ecosystem for telemedicine and non-intrusive cognitive and affective assessment. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–6.

[36]

Jaime A. Garcia. 2019. A virtual reality game-like tool for assessing the risk of falling in the elderly. Stud. Health Technol. Inform. 266 (2019), 63–69.

[37]

Jaime Andres Garcia and Karla Felix Navarro. 2014. The mobile RehApp: An AR-based mobile game for ankle sprain rehabilitation. In Proceedings of the IEEE 3rd International Conference on Serious Games and Applications for Health (SeGAH’14). IEEE, 1–6.

[38]

Irene Alice Chicchi Giglioli, Federica Pallavicini, Elisa Pedroli, Silvia Serino, and Giuseppe Riva. 2015. Augmented reality: A brand new challenge for the assessment and treatment of psychological disorder. IEEE Trans. Med. Imag. 24 (2015), 1512–1524.

[39]

Stéphane Claude Gobron, Nicolas Zannini, Nicolas Wenk, Carl Schmitt, Yannick Charrotton, Aurélien Fauquex, Michel Lauria, Francis Degache, and Rolf Frischknecht. 2015. Serious games for rehabilitation using head-mounted display and haptic devices. In Proceedings of the International Conference on Augmented and Virtual Reality. Springer, 199–219.

[40]

Diane Gromala, Xin Tong, Chris Shaw, Ashfaq Amin, Servet Ulas, and Gillian Ramsay. 2016. Mobius floe: An immersive virtual reality game for pain distraction. Electr. Imag. 2016, 4 (2016), 1–5.

[41]

Hélia Guerra, Luís Mendes Gomes, Lázaro Raposo, Diogo Leite, and Miguel Simas. 2019. An exergame with SAR bike: A first prototype. In Proceedings of the International Conference in Engineering Applications (ICEA’19). IEEE, 1–6.

[42]

Barrie Gunter. 1998. The Effects of Video Games on Children: The Myth Unmasked. A&C Black.

[43]

Bartal Henriksen, Ronni Nielsen, Martin Kraus, and Bo Geng. 2017. A virtual reality system for treatment of phantom limb pain using game training and tactile feedback. In Proceedings of the Virtual Reality International Conference (Laval Virtual’17). ACM, 13.

[44]

Machacon Herchel Thaddeus et al. 2016. Immersive and non-immersive VR environments: A preliminary EEG investigation. Bulletin Of Kiryu University 27 (2016), 13–18. https://www.jstage.jst.go.jp/article/bku/27/0/27_13/_article.

[45]

Zheng-Yu Hoe, I.-J. Lee, Chien-Hsu Chen, and Kuo-Ping Chang. 2019. Using an augmented reality-based training system to promote spatial visualization ability for the elderly. Univ. Access Inf. Soc. 18, 2 (2019), 327–342.

Digital Library

[46]

Kuei-Fang Hsiao and Habib F. Rashvand. 2015. Data modeling mobile augmented reality: Integrated mind and body rehabilitation. Multimedia Tools Appl. 74, 10 (2015), 3543–3560.

Digital Library

[47]

Kai Huotari and Juho Hamari. 2012. Defining gamification: A service marketing perspective. In Proceeding of the 16th International Academic MindTrek Conference. ACM, 17–22.

Digital Library

[48]

Sergi Bermudez i Badia, Luis Velez Quintero, Mónica S. Cameirão, Alice Chirico, Stefano Triberti, Pietro Cipresso, and Andrea Gaggioli. 2018. Toward emotionally adaptive virtual reality for mental health applications. IEEE J. Biomed. Health Inf. 23, 5 (2018), 1877–1887.

[49]

Kiran Ijaz, Yifan Wang, David Milne, and Rafael A. Calvo. 2016. VR-Rides: Interactive VR games for health. In Proceedings of the Joint International Conference on Serious Games. Springer, 289–292.

[50]

Kyle Johnsen, Sun Joo Ahn, James Moore, Scott Brown, Thomas P. Robertson, Amanda Marable, and Aryabrata Basu. 2014. Mixed reality virtual pets to reduce childhood obesity. IEEE Trans. Vis. Comput. Graph. 20, 4 (2014), 523–530.

Digital Library

[51]

Daniel Johnson, Sebastian Deterding, Kerri-Ann Kuhn, Aleksandra Staneva, Stoyan Stoyanov, and Leanne Hides. 2016. Gamification for health and wellbeing: A systematic review of the literature. Internet Intervent. 6 (2016), 89–106.

[52]

Karl M. Kapp. 2012. The Gamification of Learning and Instruction: Game-based Methods and Strategies for Training and Education. John Wiley & Sons.

Digital Library

[53]

Suzan Kardong-Edgren, Karen Breitkreuz, Michael Werb, Stephen Foreman, and Anthony Ellertson. 2019. Evaluating the usability of a second-generation virtual reality game for refreshing sterile urinary catheterization skills. Nurse Educ. 44, 3 (2019), 137–141.

[54]

Tuomas Kari. 2014. Can exergaming promote physical fitness and physical activity?: A systematic review of systematic reviews. Int. J. Gam. Comput.-Mediat. Simul. 6, 4 (2014), 59–77.

Digital Library

[55]

Staffs Keele et al. 2007. Guidelines for Performing Systematic Literature Reviews in Software Engineering. Technical Report. Technical Report, Ver. 2.3 EBSE Technical Report. EBSE.

[56]

Marie Kegeleers, Shivam Miglani, Gijs M. W. Reichert, Nestor Z. Salamon, J. Timothy Balint, Stephan G. Lukosch, and Rafael Bidarra. 2018. STAR: Superhuman training in augmented reality. In Proceedings of the 1st Superhuman Sports Design Challenge: First International Symposium on Amplifying Capabilities and Competing in Mixed Realities. ACM, 7.

[57]

Marcello Kera, Hélio Pedrini, and Fátima Nunes. 2011. Ambiente virtual interativo com colisão e deformação de objetos para treinamento médico. Revist. Inf. Teór. Aplic. 18, 2 (2011), 205–233.

[58]

Florian Kern, Carla Winter, Dominik Gall, Ivo Käthner, Paul Pauli, and Marc Erich Latoschik. 2019. Immersive virtual reality and gamification within procedurally generated environments to increase motivation during gait rehabilitation. In Proceedings of the IEEE Conference on Virtual Reality and 3D User Interfaces (VR’19). IEEE, 500–509.

[59]

Maria Merve Kihe, Ömer Can Muratlı, and Çağatay Çatal. 2017. Virtual reality based rehabilitation system for Parkinson and multiple sclerosis patients. https://ieeexplore.ieee.org/document/8093401.

[60]

Nicole Kosoris and Jeff Chastine. 2015. A study of the correlations between Augmented Reality and its ability to influence user behavior. In Proceedings of the Computer Games: AI, Animation, Mobile, Multimedia, Educational and Serious Games (CGAMES’15). IEEE, 113–118.

[61]

Fabrizio Lamberti, Davide Calandra, Federica Bazzano, Filippo G. Prattico, and Davide M. Destefanis. 2018. RobotQuest: A robotic game based on projected mixed reality and proximity interaction. In Proceedings of the IEEE Games, Entertainment, Media Conference (GEM’18). IEEE, 1–9.

[62]

John N. Latta and David J. Oberg. 1994. A conceptual virtual reality model. IEEE Comput. Graph. Appl. 14, 1 (1994), 23–29.

Digital Library

[63]

Jang Han Lee, Jeonghun Ku, Wongeun Cho, Won Yong Hahn, In Y. Kim, Sang-Min Lee, Younjoo Kang, Deog Young Kim, Taewon Yu, Brenda K. Wiederhold, et al. 2003. A virtual reality system for the assessment and rehabilitation of the activities of daily living. CyberPsychol. Behav. 6, 4 (2003), 383–388.

[64]

Sarah Lehman, Jenna Graves, Carlene Mcaleer, Tania Giovannetti, and Chiu C. Tan. 2018. A mobile augmented reality game to encourage hydration in the elderly. In Proceedings of the International Conference on Human Interface and the Management of Information. Springer, 98–107.

[65]

Xiao Li, Wen Yi, Hung-Lin Chi, Xiangyu Wang, and Albert P. C. Chan. 2018. A critical review of virtual and augmented reality (VR/AR) applications in construction safety. Autom. Construct. 86 (2018), 150–162.

[66]

Tiago Lima, Breno Barbosa, Carlos Niquini, Camila Araújo, and Raquel Lana. 2017. Playing against dengue design and development of a serious game to help tackling dengue. In Proceedings of the IEEE 5th International Conference on Serious Games and Applications for Health (SeGAH’17). IEEE, 1–8.

[67]

Tiago França Melo Lima, João Paulo Ferreira Beltrame, Carlos Ramos Niquini, Breno Gonçalves Barbosa, and Clodoveu Augusto Davis. 2018. Design of a mixed-reality serious game to tackle a public health problem. In Proceedings of the International Conference on Entertainment Computing. Springer, 305–309.

[68]

Philip Lindner, Alexander Rozental, Alice Jurell, Lena Reuterskiöld, Gerhard Andersson, William Hamilton, Alexander Miloff, and Per Carlbring. 2020. Experiences of gamified and automated virtual reality exposure therapy for spider phobia: Qualitative study. JMIR Serious Games 8, 2 (2020), e17807.

[69]

Bernard M. Maarsingh, Jannah Bos, Charlotte F. J. Van Tuijn, and Selwyn B. Renard. 2019. Changing stress mindset through stressjam: A virtual reality game using biofeedback. Games Health J. 8, 5 (2019), 326–331.

[70]

Iain J. Marshall and Byron C. Wallace. 2019. Toward systematic review automation: A practical guide to using machine learning tools in research synthesis. Systemat. Rev. 8, 1 (2019), 1–10.

[71]

Chidozie Emmanuel Mbada, Moses Oluwatosin Makinde, Adesola Christianah Odole, Olumide Olasunkanmi Dada, Olusola Ayanniyi, Ayomide Johnson Salami, and Ishaya Peni Gambo. 2019. Comparative effects of clinic-and virtual reality-based McKenzie extension therapy in chronic non-specific low-back pain. Human Move. 20, 2 (2019).

[72]

Don D. McMahon, Brenda Barrio, Amanda K. McMahon, Kristen Tutt, and Jonah Firestone. 2020. Virtual reality exercise games for high school students with intellectual and developmental disabilities. J. Spec. Educ. Technol. 35, 2 (2020), 87–96.

[73]

Reika Nicole McNish, Pramod Chembrammel, Nathaniel Christopher Speidel, Julian Jwchun Lin, and Citlali López-Ortiz. 2019. Rehabilitation for children with dystonic cerebral palsy using haptic feedback in virtual reality: Protocol for a randomized controlled trial. JMIR Res. Protocols 8, 1 (2019), e11470.

[74]

David R. Michael and Sandra L. Chen. 2005. Serious Games: Games That Educate, Train, and Inform. Muska & Lipman/Premier-Trade.

[75]

Zeljka Mihajlovic, Sinisa Popovic, Karla Brkic, and Kresimir Cosic. 2018. A system for head-neck rehabilitation exercises based on serious gaming and virtual reality. Multimedia Tools Appl. 77, 15 (2018), 19113–19137.

Digital Library

[76]

Paul Milgram and Fumio Kishino. 1994. A taxonomy of mixed reality visual displays. IEICE Trans. Inf. Syst. 77, 12 (1994), 1321–1329.

[77]

Béatrice Moissinac, Kimmy Hescock, Jon Dorbolo, Siew Sun Wong, and Melinda Manore. 2016. Strategies to design a mixed-reality immersive environment and influence teen health behaviors. In Proceedings of the International Conference on Immersive Learning. Springer, 17–28.

[78]

Marta Mondellini, Sara Arlati, Simone Pizzagalli, Luca Greci, Marco Sacco, and Giancarlo Ferrigno. 2018. Assessment of the usability of an immersive virtual supermarket for the cognitive rehabilitation of elderly patients: A pilot study on young adults. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–8.

[79]

J. M. Fernandez Montenegro and Vasileios Argyriou. 2015. Cognitive tests for the diagnosis of Alzheimer’s disease based on virtual environments. 1–5. https://ieeexplore.ieee.org/abstract/document/7389244.

[80]

Mikyeong Moon and Chongsan Kwon. [n. d.]. Developing a puzzle using the mixed reality technology for the elderly with mild cognitive impairment. International Journal of Innovative Technology and Exploring Engineering 8, 5 (2019), 889–893. https://www.ijitee.org/wp-content/uploads/papers/v8i8s2/H11500688S219.pdf.

[81]

Jacquelyn Ford Morie. 1994. Inspiring the future: Merging mass communication, art, entertainment and virtual environments. ACM SIGGRAPH Comput. Graph. 28, 2 (1994), 135–138.

Digital Library

[82]

Fariba Mostajeran, Aila Kirsten, Frank Steinicke, Jürgen Gallinat, and Simone Kühn. 2019. Towards gamified alcohol use disorder therapy in virtual reality: A preliminary usability study. In Proceedings of the IEEE Conference on Virtual Reality and 3D User Interfaces (VR’19). IEEE, 1471–1476.

[83]

Florian’Floyd’ Mueller, Darren Edge, Frank Vetere, Martin R. Gibbs, Stefan Agamanolis, Bert Bongers, and Jennifer G. Sheridan. 2011. Designing sports: A framework for exertion games. In Proceedings of the SIGCHI Conference on Human Factors in Computing Systems. ACM, 2651–2660.

Digital Library

[84]

Yasheni Nair Indran Nair, Feninferina Azman, Fiza Abdul Rahim, and Lim Kok Cheng. 2019. Endure: Augmented reality fitness mobile application. In Proceedings of the IEEE 4th International Conference on Computer and Communication Systems (ICCCS’19). IEEE, 419–424.

[85]

OECD and World Health Organization. 2000. Ageing.

[86]

Leticia Neira-Tovar and Marco Eduardo Elizondo Elizondo. 2018. A virtual reality serious game to prevent type 2 diabetes mellitus. In Smart Technology. Springer, 178–188.

[87]

Leticia Neira-Tovar and Ivan Castilla Rodriguez. 2017. A virtual reality tool applied to improve the effects on chronic diseases-case: Emotional effects on T2DM. In Proceedings of the International Conference on Virtual, Augmented and Mixed Reality. Springer, 417–425.

[88]

Scott Nicholson. 2015. A recipe for meaningful gamification. In Gamification in Education and Business. Springer, 1–20.

[89]

Takuya Nojima, Kadri Rebane, Ryota Shijo, Tim Schewe, Shota Azuma, Yo Inoue, Takahiro Kai, Naoki Endo, and Yohei Yanase. 2018. Designing augmented sports: Merging physical sports and virtual world game concept. In Proceedings of the International Conference on Human Interface and the Management of Information. Springer, 403–414.

[90]

Yoonsin Oh and Stephen Yang. 2010. Defining exergames & exergaming. Proc. Meaningful Play (2010), 1–17.

[91]

A. Okeil. 2010. Hybrid design environments: Immersive and non-immersive architectural design. J. Inf. Technol. Construct. 15, 16 (2010), 202–216.

[92]

Babatunde Kazeem Olorisade et al. 2019. Study on Automatic Citation Screening in Systematic Reviews: Reporting, Reproducibility and Complexity. Ph.D. Dissertation. Keele University.

[93]

Edwin Daniel Oña, Alicia Cuesta-Gomez, Jaime A. Garcia, William Raffe, Patricia Sánchez-Herrera, Roberto Cano-de-la Cuerda, and Alberto Jardón. 2019. Evaluating a VR-based box and blocks test for automatic assessment of manual dexterity: A preliminary study in Parkinson’s disease. In Proceedings of the IEEE 7th International Conference on Serious Games and Applications for Health (SeGAH’19). IEEE, 1–6.

[94]

Cong Peng, Dangxiao Wang, Yuru Zhang, and Jing Xiao. 2019. A visuo-haptic attention training game with dynamic adjustment of difficulty. IEEE Access 7 (2019), 68878–68891.

[95]

PERKINSCOIE and XR Association. 2019. 2019 Augmented and Virtual Reality Survey Report. https://www.perkinscoie.com/images/content/2/1/v4/218679/2019-VR-AR-Survey-Digital-v1.pdf.

[96]

PERKINSCOIE, BoostVC and XR Association. 2019. 2020 Augmented and Virtual Reality Survey Report. https://www.perkinscoie.com/images/content/2/3/v4/231654/2020-AR-VR-Survey-v3.pdf.

[97]

Théo Perrin, Charles Faure, Kévin Nay, Giammaria Cattozzo, Anthony Sorel, Richard Kulpa, and Hugo A. Kerhervé. 2019. Virtual reality gaming elevates heart rate but not energy expenditure compared to conventional exercise in adult males. Int. J. Environ. Res. Publ. Health 16, 22 (2019), 4406.

[98]

Mores Prachyabrued, Disathon Wattanadhirach, Richard B. Dudrow, Nat Krairojananan, and Pusit Fuengfoo. 2019. Toward virtual stress inoculation training of prehospital healthcare personnel: A stress-inducing environment design and investigation of an emotional connection factor. In Proceedings of the IEEE Conference on Virtual Reality and 3D User Interfaces (VR’19). IEEE, 671–679.

[99]

Uvais Qidwai, M. S. Ajimsha, and Mohamed Shakir. 2019. The role of EEG and EMG combined virtual reality gaming system in facial palsy rehabilitation-A case report. J. Bodywork Movem. Therap. 23, 2 (2019), 425–431.

[100]

William L. Raffe and Jaime A. Garcia. 2018. Combining skeletal tracking and virtual reality for game-based fall prevention training for the elderly. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–7.

[101]

Edgar Rodríguez Ramírez, Regan Petrie, Kah Chan, and Nada Signal. 2018. A tangible interface and augmented reality game for facilitating sit-to-stand exercises for stroke rehabilitation. In Proceedings of the 8th International Conference on the Internet of Things. ACM, 28.

[102]

Scott Rigby and Richard M. Ryan. 2011. Glued to Games: How Video Games Draw Us in and Hold Us Spellbound: How Video Games Draw Us in and Hold Us Spellbound. AbC-CLIo.

[103]

F. D. Rose, E. A. Attree, and D. A. Johnson. 1996. Virtual reality: An assistive technology in neurological rehabilitation. Curr. Opin. Neurol. 9, 6 (1996), 461–467.

[104]

Henrique S. Rossi, Sibele M. dos Santos, Raquel O. Prates, and Renato A. C. Ferreira. 2018. Imaginator: A virtual reality based game for the treatment of sensory processing disorders. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–8.

[105]

R. Sacks and E. Pikas. 2013. Building information modeling education for construction engineering and management. I: Industry requirements, state of the art, and gap analysis. J. Construct. Eng. Manage. 139, 11 (2013), 04013016.

[106]

Michael Sailer, Jan Hense, J. Mandl, and Markus Klevers. 2014. Psychological perspectives on motivation through gamification. Interact. Des. Arch. J.19 (2014), 28–37.

[107]

Michael Sailer, Jan Ulrich Hense, Sarah Katharina Mayr, and Heinz Mandl. 2017. How gamification motivates: An experimental study of the effects of specific game design elements on psychological need satisfaction. Comput. Hum. Behav. 69 (2017), 371–380.

Digital Library

[108]

Arata Andrade Saraiva, Alexandre Tolstenko Nogueira, N. M. Fonseca Ferreira, and Antonio Valente. 2018. Application of virtual reality for the treatment of Strabismus and Amblyopia. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–7.

[109]

Dianis Wulan Sari, Ayumi Igarashi, Manami Takaoka, Reiko Yamahana, Maiko Noguchi-Watanabe, Chie Teramoto, and Noriko Yamamoto-Mitani. 2020. Virtual reality program to develop dementia-friendly communities in Japan. Australas. J. Age. (2020).

[110]

András Sárkány, Zoltán Tősér, Anita L. Verő, András Lőrincz, Takumi Toyama, Ehsan N. Toosi, and Daniel Sonntag. 2015. Maintain and improve mental health by smart virtual reality serious games. In Proceedings of the International Symposium on Pervasive Computing Paradigms for Mental Health. Springer, 220–229.

[111]

Jonas Schild, Dieter Lerner, Sebastian Misztal, and Thomas Luiz. 2018. EPICSAVE—Enhancing vocational training for paramedics with multi-user virtual reality. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–8.

[112]

Silvia Serino, Elisa Pedroli, Pietro Cipresso, Federica Pallavicini, Giovanni Albani, Alessandro Mauro, and Giuseppe Riva. 2014. The role of virtual reality in neuropsychology: The virtual multiple errands test for the assessment of executive functions in Parkinson’s disease. In Virtual, Augmented Reality and Serious Games for Healthcare 1. Springer, 257–274.

[113]

Robert Shewaga, Alvaro Uribe-Quevedo, Bill Kapralos, and Fahad Alam. 2018. A comparison of seated and room-scale virtual reality in a serious game for epidural preparation. IEEE Trans. Emerg. Top. Comput. 8, 1 (2018), 218–232. https://store.computer.org/csdl/journal/ec/2020/01/08017559/13rRUxBJhBQ.

[114]

Maria Sisto, Mohsen Zare, Nabil Ouerhani, Christophe Bolinhas, Margaux Divernois, Bernard Mignot, Jean-Claude Sagot, and Stéphane Gobron. 2018. Virtual reality serious game for musculoskeletal disorder prevention. In Proceedings of the International Conference on Augmented Reality, Virtual Reality and Computer Graphics. Springer, 43–59.

[115]

Stanisław Skulimowski and Marcin Badurowicz. 2017. Wearable sensors as feedback method in virtual reality anti-stress therapy. In Proceedings of the International Conference on Electromagnetic Devices and Processes in Environment Protection with Seminar Applications of Superconductors (ELMECO & AoS’17). IEEE, 1–4.

[116]

Glenn E. Smith, Patricia Housen, Kristine Yaffe, Ronald Ruff, Robert F. Kennison, Henry W. Mahncke, and Elizabeth M. Zelinski. 2009. A cognitive training program based on principles of brain plasticity: Results from the Improvement in Memory with Plasticity-based Adaptive Cognitive Training (IMPACT) Study. J. Am. Geriatr. Soc. 57, 4 (2009), 594–603.

[117]

Hannah Snyder. 2019. Literature review as a research methodology: An overview and guidelines. J. Bus. Res. 104 (2019), 333–339.

[118]

Matthias Süncksen, Henner Bendig, Michael Teistler, Markus Wagner, Oliver Johannes Bott, and Klaus Dresing. 2018. Gamification and virtual reality for teaching mobile x-ray imaging. In Proceedings of the IEEE 6th International Conference on Serious Games and Applications for Health (SeGAH’18). IEEE, 1–7.

[119]

Momen Kamal Tageldeen, I. Elamvazuthi, N. Perumal, and T. Ganesan. 2017. A virtual reality based serious games for rehabilitation of arm. In Proceedings of the IEEE 3rd International Symposium in Robotics and Manufacturing Automation (ROMA’17). IEEE, 1–6.

[120]

Jeff K. T. Tang, Green Y. Y. Leung, Bismarck K. L. Ng, Jacky Hon-Kit Hui, Anthony Kong, and Wai-Man Pang. 2016. VR-MMA: A virtual reality motion and muscle sensing action game for personal sport. In Proceedings of the 13th International Conference on Advances in Computer Entertainment Technology. ACM, 40.

[121]

Ngeemasara Thapa, Hye Jin Park, Ja-Gyeong Yang, Haeun Son, Minwoo Jang, Jihyeon Lee, Seung Wan Kang, Kyung Won Park, and Hyuntae Park. 2020. The effect of a virtual reality-based intervention program on cognition in older adults with mild cognitive impairment: A randomized control trial. J. Clin. Med. 9, 5 (2020), 1283.

[122]

Xin Tong, Diane Gromala, Ashfaq Amin, and Amber Choo. 2015. The design of an immersive mobile virtual reality serious game in cardboard head-mounted display for pain management. In Proceedings of the International Symposium on Pervasive Computing Paradigms for Mental Health. Springer, 284–293.

[123]

Jörg Trojan, Martin Diers, Xaver Fuchs, Felix Bach, Robin Bekrater-Bodmann, Jens Foell, Sandra Kamping, Mariela Rance, Heiko Maaß, and Herta Flor. 2014. An augmented reality home-training system based on the mirror training and imagery approach. Behav. Res. Methods 46, 3 (2014), 634–640.

[124]

Mateus Trombetta, Patrícia Paula Bazzanello Henrique, Manoela Rogofski Brum, Eliane Lucia Colussi, Ana Carolina Bertoletti De Marchi, and Rafael Rieder. 2017. Motion rehab AVE 3D: A VR-based exergame for post-stroke rehabilitation. Comput. Methods Progr. Biomed. 151 (2017), 15–20.

Digital Library

[125]

Elena Tuveri, Luca Macis, Fabio Sorrentino, Lucio Davide Spano, and Riccardo Scateni. 2016. Fitmersive games: Fitness gamification through immersive VR. In Proceedings of the International Working Conference on Advanced Visual Interfaces. ACM, 212–215.

[126]

Marieke Van Rooij, Adam Lobel, Owen Harris, Niki Smit, and Isabela Granic. 2016. DEEP: A biofeedback virtual reality game for children at-risk for anxiety. In Proceedings of the CHI Conference Extended Abstracts on Human Factors in Computing Systems. ACM, 1989–1997.

[127]

Carmen Nélida Waliño-Paniagua, Cristina Gomez-Calero, María Isabel Jiménez-Trujillo, Leticia Aguirre-Tejedor, Alberto Bermejo-Franco, Rosa María Ortiz-Gutiérrez, and Roberto Cano-de-la Cuerda. 2019. Effects of a game-based virtual reality video capture training program plus occupational therapy on manual dexterity in patients with multiple sclerosis: A randomized controlled trial. J. Healthcare Eng. (2019). https://www.hindawi.com/journals/jhe/2019/9780587/.

[128]

Peng Wang, Peng Wu, Jun Wang, Hung-Lin Chi, and Xiangyu Wang. 2018. A critical review of the use of virtual reality in construction engineering education and training. Int. J. Environ. Res. Publ. Health 15, 6 (2018), 1204.

[129]

Patrice L. Weiss, Emanuel Tirosh, and Darcy Fehlings. 2014. Role of virtual reality for cerebral palsy management. J. Child Neurol. 29, 8 (2014), 1119–1124.

[130]

Kevin Werbach and Dan Hunter. 2015. The Gamification Toolkit: Dynamics, Mechanics, and Components for the Win. Wharton School Press.

[131]

Richard Wetzel and Tobias Kreienbühl. 2019. Breathe to dive: Exploring a virtual reality game for treatment of cystic fibrosis. In Proceedings of the IEEE International Symposium on Mixed and Augmented Reality Adjunct (ISMAR-Adjunct’19). IEEE, 412–416.

[132]

Mark D. Wiederhold, Megan Crisci, Vrajeshri Patel, Makoto Nonaka, and Brenda K. Wiederhold. 2019. Physiological monitoring during augmented reality exercise confirms advantages to health and well-being. Cyberpsychol. Behav. Soc. Netw. 22, 2 (2019), 122–126.

[133]

Mikyeong Moon and Chongsan Kwon. 2019. Developing a puzzle using the mixed reality technology for the elderly with mild cognitive impairment. International Journal of Innovative Technology and Exploring Engineering 8, 5 (2019), 889–893.

[134]

Bob Woods, Elisa Aguirre, Aimee E. Spector, and Martin Orrell. 2012. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Datab. Syst. Rev.2 (2012).

[135]

Szu-Hsien Wu, Chia-Chang Huang, Shiau-Shian Huang, Ying-Ying Yang, Chih-Wei Liu, Boaz Shulruf, and Chen-Huan Chen. 2020. Effect of virtual reality training to decreases rates of needle stick/sharp injuries in new-coming medical and nursing interns in Taiwan. J. Educ. Eval. Health Profess. 17 (2020), 1.

[136]

Wenge Xu, Hai-Ning Liang, Zeying Zhang, and Nilufar Baghaei. 2020. Studying the effect of display type and viewing perspective on user experience in virtual reality exergames. Games Health J. (2020).

[137]

Fengming Yang and Wenjuan Wu. 2010. The application of virtual reality in e-learning. In Proceedings of the International Conference on E-Business and E-Government. IEEE, 5548–5551.

[138]

Soojeong Yoo and Judy Kay. 2016. VRun: Running-in-place virtual reality exergame. In Proceedings of the 28th Australian Conference on Computer-Human Interaction. ACM, 562–566.

[139]

Soojeong Yoo, Callum Parker, and Judy Kay. 2017. Designing a personalized VR exergame. In Adjunct Publication of the 25th Conference on User Modeling, Adaptation and Personalization. ACM, 431–435.

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Cited By

Ramya RRamamoorthy S(2025)AI in Communication Technology and Innovation of AR/VR in CommunicationImpact of Digitalization on Communication Dynamics10.4018/979-8-3693-3579-6.ch001(1-28)Online publication date: 3-Jan-2025
https://doi.org/10.4018/979-8-3693-3579-6.ch001
Ljungblad LMurphy DFonkalsrud H(2025)A mixed reality for midwifery students: a qualitative study of the technology’s perceived appropriateness in the classroomBMC Medical Education10.1186/s12909-025-06919-z25:1Online publication date: 5-Mar-2025
https://doi.org/10.1186/s12909-025-06919-z
Sousa DTeixeira Sde Oliveira ALima LMoreira RSilva FTeles A(2025)Computer-Based Gamified Tools for Facial Rehabilitation: A Scoping ReviewGames for Health Journal10.1089/g4h.2023.022014:1(11-20)Online publication date: 1-Feb-2025
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Index Terms

A Systematic Literature Review of Virtual, Augmented, and Mixed Reality Game Applications in Healthcare
1. Applied computing
  1. Life and medical sciences
2. Human-centered computing
  1. Human computer interaction (HCI)
    1. HCI design and evaluation methods

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cover image ACM Transactions on Computing for Healthcare

ACM Transactions on Computing for Healthcare Volume 3, Issue 2

April 2022

292 pages

EISSN:2637-8051

DOI:10.1145/3505188

Editors:
Insup Lee
University of Pennsylvania, USA
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John A. Stankovic
University of Virginia, USA

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Publication History

Published: 03 March 2022

Accepted: 01 June 2021

Revised: 01 May 2021

Received: 01 January 2021

Published in HEALTH Volume 3, Issue 2

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Ramya RRamamoorthy S(2025)AI in Communication Technology and Innovation of AR/VR in CommunicationImpact of Digitalization on Communication Dynamics10.4018/979-8-3693-3579-6.ch001(1-28)Online publication date: 3-Jan-2025
https://doi.org/10.4018/979-8-3693-3579-6.ch001
Ljungblad LMurphy DFonkalsrud H(2025)A mixed reality for midwifery students: a qualitative study of the technology’s perceived appropriateness in the classroomBMC Medical Education10.1186/s12909-025-06919-z25:1Online publication date: 5-Mar-2025
https://doi.org/10.1186/s12909-025-06919-z
Sousa DTeixeira Sde Oliveira ALima LMoreira RSilva FTeles A(2025)Computer-Based Gamified Tools for Facial Rehabilitation: A Scoping ReviewGames for Health Journal10.1089/g4h.2023.022014:1(11-20)Online publication date: 1-Feb-2025
https://doi.org/10.1089/g4h.2023.0220
Arnold RKempf RWaltenspül RSchuldt H(2025)MediaMix: Multimedia Retrieval in Mixed RealityMultiMedia Modeling10.1007/978-981-96-2074-6_37(310-317)Online publication date: 9-Jan-2025
https://dl.acm.org/doi/10.1007/978-981-96-2074-6_37
Miller JFernando EMiranda JBansil JHernandez HRegala A(2024)Extended Reality Technologies in Physical Fitness for Health PromotionEmerging Technologies for Health Literacy and Medical Practice10.4018/979-8-3693-1214-8.ch005(86-108)Online publication date: 23-Feb-2024
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Marti PTeverini GGoracci CFranchi L(2024)Gamification of Orthodontic Treatment with Personalised Facemasks: Enhancing Patient Compliance Through Playful EngagementFuture Internet10.3390/fi1612044616:12(446)Online publication date: 29-Nov-2024
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Albanese GBucchieri APodda JTacchino ABuccelli SDe Momi ELaffranchi MMannella KHolmes MZenzeri JDe Michieli LBrichetto GBarresi G(2024)Robotic systems for upper-limb rehabilitation in multiple sclerosis: a SWOT analysis and the synergies with virtual and augmented environmentsFrontiers in Robotics and AI10.3389/frobt.2024.133514711Online publication date: 27-Feb-2024
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Vaughan N(2024)Virtual Reality Meets DiabetesJournal of Diabetes Science and Technology10.1177/19322968231222022Online publication date: 9-Jan-2024
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Sehrt JMbamara ERafati MSchwind V(2024)From Skepticism to Acceptance: On the Dynamics of Elderly Engagement with Mixed RealityProceedings of Mensch und Computer 202410.1145/3670653.3670666(67-82)Online publication date: 1-Sep-2024
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Li MGoodwin SDwyer TEvans J(2024)Exploring Human Values in Mixed Reality FuturesProceedings of the 2024 ACM Designing Interactive Systems Conference10.1145/3643834.3660712(197-213)Online publication date: 1-Jul-2024
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