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Study on the Causal Relationship of Cardiovascular Disease Influencing Factors Based on Bayesian Causal Network

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Published:31 May 2022Publication History

ABSTRACT

The WHO MONICA dataset was used as an example, and a logistic regression model was used to statistically analyze the data, and then a Bayesian causal network model was constructed using the MMHC hybrid algorithm to analyze the causal relationships among cardiovascular disease risk factors, and Bayesian estimation was used to learn the conditional probabilities of each node of the network so as to predict the survival of patients, and to compare the Bayesian causal network model with respect to logistic regression model in the field of chronic diseases. Bayesian causal network model results showed that hospitalization status, age at diagnosis, and angina status were direct causes of cardiovascular mortality, while previous myocardial infarction, sex, and smoking had indirect effects on cardiovascular mortality through other variables. Compared to logistic regression models, Bayesian causal networks based on the MMHC algorithm are more applicable in clinical research because they can intuitively and effectively identify and define the complex causal relationships between survival outcomes and cardiovascular disease and cardiovascular disease with each other. By analyzing this relationship, we are able to implement timely and targeted preventive and therapeutic measures and avoid possible mortality outcomes in high-risk populations.

References

  1. Bacciu, D., Etchells, T. A., & Paulo J. G. Lisboa…. (2013). Efficient identification of independence networks using mutual information. Computational Statistics, 28(2), 621-646.Google ScholarGoogle ScholarDigital LibraryDigital Library
  2. Biery, D. W., Berman, A. N. , Singh, A., Divakaran, S. , & Blankstein, R..(2020). Association of smoking cessation and survival among young adults with myocardial infarction in the partners young-mi registry. JAMA Network Open, 3(7), e209649.Google ScholarGoogle ScholarCross RefCross Ref
  3. Dagenais, Gilles R., (2020).Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study. The Lancet, 395(10226):785-794.Google ScholarGoogle ScholarCross RefCross Ref
  4. Hoshino, A. , Wang, W. J. , Wada, S. , Mcdermott-Roe, C. , & Arany, Z. . (2019). The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature, 575(7782), -.Google ScholarGoogle Scholar
  5. Hu Shengshou. (2020). Report on Cardiovascular Health and Diseases in China 2019:an Updated Summary. Chinese Circulation Journal, 35(9),22.Google ScholarGoogle Scholar
  6. Kalisch, Markus, Bühlman, & Peter. (2007). Estimating high-dimensional directed acyclic graphs with the pc-algorithm. Journal of Machine Learning Research.Google ScholarGoogle Scholar
  7. Marjan Walli-Attaei, , (2020). Variations between women and men in risk factors, treatments, cardiovascular disease incidence, and death in 27 high-income, middle-income, and low-income countries (PURE): a prospective cohort study. The Lancet, DOI: 10.1016/S0140-6736(20)30543-2Google ScholarGoogle ScholarCross RefCross Ref
  8. Moran, Andrew, E., Forouzanfar, Mohammad, & H., (2014). The global burden of ischemic heart disease in 1990 and 2010. Circulation, 129(14), 1493-1501.Google ScholarGoogle ScholarCross RefCross Ref
  9. Neeland, I. J. , Ross, R. , JP Després, Matsuzawa, Y. , & Eckel, R. H. . (2019). Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement. The Lancet Diabetes & Endocrinology, 7(9).Google ScholarGoogle Scholar
  10. Spirtes, P. , Glymour, C. , & Scheines, R. . (2000). Causation, Prediction, and Search. The MIT Press. 2nd edition.Google ScholarGoogle Scholar
  11. Tsamardinos, I. . (2006). The max-min hill-climbing bayesian network structure learning algorithm. Machine Learning, 65(1), pp. 31-78.Google ScholarGoogle ScholarDigital LibraryDigital Library
  12. Wang Dezheng, Shen Chengfeng, Zhang Ying, .(2017). Fifteen-year trend in incidence of acute myocardial infarction in Tianjin of China [J]. Chinese Journal of Cardiology, 45(2):154-159.Google ScholarGoogle Scholar
  13. Wenchi, G. , Venkatesh, A. K. , Xueke, B. , Si, X. , Jing, L. , & Xi, L. , (2018). Time to hospital arrival among patients with acute myocardial infarction in China: a report from China peace prospective study. European Heart Journal Quality of Care & Clinical Outcomes.Google ScholarGoogle Scholar
  14. Yasin, A. , & Leray, P. . (2011). IMMPC: A Local Search Approach for Incremental Bayesian Network Structure Learning. Springer, Berlin, Heidelberg, 2011:401-412.Google ScholarGoogle ScholarCross RefCross Ref

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              cover image ACM Other conferences
              BIC 2022: 2022 2nd International Conference on Bioinformatics and Intelligent Computing
              January 2022
              551 pages
              ISBN:9781450395755
              DOI:10.1145/3523286

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              Publication History

              • Published: 31 May 2022

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