Runping Yuan
ABSTRACT
[Objective] To evaluate the effect of bilateral upper limb robot-assisted rehabilitation on upper extremity motor function recovery and neuromuscular electrophysiological changes in stroke patients, compared to the routine therapy. [Methods] Forty stroke patients were enrolled and randomized into two groups, both exposed to standard therapy, in comparison with the conventional therapy (CT) group provided with routine therapy, the robot-assist therapy(RAT) group received additional robot-assisted therapy distributed in sessions,30 min per day,6 days a week, for 3 weeks. To evaluate motor function and neuromuscular electrophysiological changes, the following evaluations were performed: simplified upper limb Fugl-meyer(FMA-UE),surface electromyography measurements recorded from biceps brachii(BB),triceps brachii(TB),anterior deltoid bundle(ADB),and middle deltoid bundle(MDB),and motor evoked potentials(MEPs) [Results] (1) Comparison of FMA-UE: evidence of improvements in FMA-UE was found in both RAT and CT (P<0.05),with a significantly higher improvement in the RAT(P<0.05).(2)Comparison of surface electromyography measurements: root mean square (RMS) and integral electromyography(iEMG) of BB, TB, ADB and MDB on the affected side of the two groups were higher than those before treatment (P<0.05),with a remarkabiy higher levels in the RAT(P<0.05); (3) Comparison of MEP: After treatment, the motor evoked potential elicitation rates in the RAT and the CT increased from 5/20 (25%) and 6/20 (30%) before treatment to 12/20 (60%) and 7/20 (35%),Significantly improved compared with before treatment (X2=5.625, P=0.018).[Conclusion]The bilateral upper limb robot-assisted rehabilitation training can effectively improve the muscle strength by promoting the functional remodeling of the corticospinal tract and enhancing the muscle excitation recruitment, and improve the motor function of the upper limbs after stroke.
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