Zhe Zhao
ABSTRACT
Chromosome enumeration is a tedious and necessary step in karyotype analysis. Abnormal detection usually starts with enumeration of chromosome number. Chromosome images have the characteristics of high cohesion, overlap and nesting, which is a difficulty in chromosome enumeration at this stage. In this work, tandem rule is used to remove redundant and irrelevant objects from the preprocessed karyotype image; A chromosome enumeration method based on morphology is proposed. Starting from overlapping features, the relationship between intersection points and curves is solved to complete enumeration. This work is verified on 200 images, and the results show that the recognition rate of overlapping chromosome clusters is 98.5%, and the recognition rate of complex chromosome clusters is 90.5%. This shows the effectiveness of the algorithm.
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Index Terms
- A Chromosome Enumeration Method Based On Morphology
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