Zichun Yan
ABSTRACT
This study used UPDRS III scale, scale B and scale C to investigate 30 cases of PD patients, 50 cases of RBD patients and 50 cases of normal people, and analyzed the difference of barrier scores between PD patients and RBD patients. The differences in reading ability and monologue ability among the three groups of research subjects were analyzed. The three scales are subjected to exploratory factor analysis to verify whether the structure of the three scales is good or not. The analysis results show that the impairment score of PD patients is higher than that of RBD patients, that is, the severity of impairment in PD patients is higher than that of RBD patients; Statistical differences exist in reading ability among the three groups, suggesting that the reading ability of the three groups is different; Statistical differences in the monologue ability among the three groups of people indicate the monologue ability of the three groups of people is different. In the analysis, 7, 4 and 4 common factors were extracted from UPDRS III scale, scale B and scale C respectively, which explained 68.955% and 68.955% of the total variation of UPDRS III scale, scale B and scale C. 73.589% and 72.298% respectively. It shows that the structure of the three scales is good and reasonable, and the collected data can be used, and the data are representative.
- Peng Kai, Yan Weihong. Clinical research progress of Parkinson's disease with rapid eye movement sleep behavior disorder [J]. Journal of Cardiovascular and Cerebrovascular Diseases of Integrated Traditional Chinese and Western Medicine, 2022.Google Scholar
- Nomura Takashi, Kishi Masafumi, Nakashima Kenji. Differences in clinical characteristics when REM sleep behavior disorder precedes or comes after the onset of Parkinson's disease[J]. Journal of the Neurological Sciences, 2017, 382:58-60.Google ScholarCross Ref
- Liu Wenlong, Liang Zhanhua, Jiang Changbin, Hu Yaping, Zou Shuang, Wang Ying. Multiple hypnogram studies on behavioral disturbances during rapid eye movement sleep in patients with Parkinson's disease [J]. Journal of Epilepsy and Neuroelectrophysiology, 2018, 27(1): 23-27; 33.Google Scholar
- J Jeppesen, M Otto, Y Frederiksen, AK Hansen, M Sommerauer. Observations on muscle activity in REM sleep behavior disorder assessed with a semi-automated scoring algorithm[J]. Clinical Neurophysiology, 2018, 129(3):541-547.Google ScholarCross Ref
- Jon M. Kleinberg. 1999. Authoritative sources in a hyperlinked environment. J. ACM 46, 5 (September 1999), 604–632. https://doi.org/10.1145/324133.324140Google ScholarDigital Library
- Elio, Acquas, and, Augusta, Pisanu, and, Paola, Marrocu, and, Gaetano, Di, Chiara. Cannabinoid CB1 receptor agonists increase rat cortical and hippocampal acetylcholine release in vivo[J]. European Journal of Pharmacology, 2000, 401(2):179-185.Google ScholarCross Ref
- Rusz Jan, Hlavnicka Jan, Novotny Michal, Tykalova Tereza, Pelletier Amelie, Montplaisir Jacques. Speech Biomarkers in Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease[J]. Annals of Neurology, 2021, 90(1):62-75.Google ScholarCross Ref
- STEFANI A, HOGL B. Sleep in Parkinson' s disease[J]. Neuropsychopharmacology, 2020, 45(1):121-128.Google ScholarCross Ref
- Pan Heyue, Wang Xiaohua, Wang Shouyong, Li Hongliang, Shi Xiangsong. Effectiveness Analysis of Dobaserazide Tablets Combined with Pramipexole in the Treatment of Parkinson [J]. Chinese and Foreign Medical Research, 2019, 17(32):34-36.Google Scholar
- Peng Shuangshuang. Correlation analysis of Parkinson's symptoms and their impact on patients' lives, 2021. Southwest Medical University.Google Scholar
- Xiao Caixia, Zhang Jiangang, Li Jiajia. The effect of dopaserazide combined with pramipexole on cognitive function and motor function in patients with Parkinson's disease [J]. Practical Integrative Chinese and Western Medicine Clinic, 2021, 21(7): 89- 90.Google Scholar
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