ABSTRACT
Estimating dimensional measurements of the choroid provides diagnostic values which can be used to assess choroidal health. In this paper we describe a methodology of calculating measurements from choroid segmentations automatically generated using convolutional neural network (CNN). We use a three-dimensional (3D) U-Net architecture built from residual units to segment the choroid. A surface fitting phase is jointed to the main process to compensate segmented defects at the area of Optic Nerve Hypoplasia (ONH). Consequently, we process these segmentations to estimate the mean choroidal thickness(MCT). The model is evaluated on volumetric scans from 183 subjects, approximately half of which are thyroid eyes. In the choroidal layer segmentation experiment, the accuracy of the automatic segmentation algorithm proposed in this paper was 98.25% when comparing the manual segmentation results masked by doctors. It showed that the MCT in thyroid eyes were higher than those in normal eyes.
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Index Terms
- Volumetric choroidal segmentation using 3D residual U-Net
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