Dandan Chen
ABSTRACT
Background and purpose: Depression can give rise to a wide variety of negative health results, including abdominal obesity, elevated blood glucose, elevated blood pressure, or dyslipidemia. Nevertheless, evidence supporting the relationship between depression and metabolic syndrome (MetS), a series of cardiometabolic risk factors, remains insufficient. The present research in order to inspect the associations between MetS and depression out of community-dwelling Chinese super-old adults.
Methods: This study used the data from 1,172 super-old (aged ≥ 80 years) Chinese adults from the China Health and Retirement Longitudinal Study (CHARLS) in 2011. The MetS refers to the presence of at least three of the five selected indications: hypertension, central obesity, raised triglyceride, reduced HDL-cholesterol, and raised fasting plasma glucose. We measured metabolic syndrome, depressive symptoms, and covariates. Odds ratio (OR) and 95% confidence interval (95% CI) were performed using Logistic regression analyses, after adjusting all potential confounders.
Results: MetS had a significant association with depression (OR = 0.682, 95% CI = 0.529-0.880). After fully adjusted for gender, education level, married, current drinkers, current smokers, and social isolation, the logistic regression analyses showed that super-old adults with MetS had also an increased risk of depression (OR = 0.674, 95% CI = 0.521-0.872), compared with those without MetS.
Conclusions: MetS was prevalent among older Chinese super-old adults and was an independent risk factor of depression. To study cause and effect and investigate possible action mechanisms, longitudinal studies with a bigger number of people are required in the future.
- Huang PL. A comprehensive definition for metabolic syndrome. Dis Model Mech. 2009; 2(5-6):231-237. doi:10.1242/dmm.001180.Google Scholar
Cross Ref
- Marazziti D, Rutigliano G, Baroni S, Metabolic syndrome and major depression. CNS Spectr. 2014; 19(4):293-304. doi:10.1017/S1092852913000667.Google ScholarCross Ref
- Zhang Q, Zhao X, Liu H, et,al. Association between the metabolic syndrome and muscle weakness among Chinese older adults: results from the China Health and Retirement Longitudinal Study. Geriatr Nurs. 2021;42(6):1415-1421. doi:10.1016/j.gerinurse. 2021. 09.006.Google ScholarCross Ref
- Ge H, Yang Z, Li X, The prevalence and associated factors of metabolic syndrome in Chinese aging population. Sci Rep. 2020; 10(1):20034. doi:10.1038/s41598-020-77184-x.Google ScholarCross Ref
- Mezhal F, Ahmad A, Abdulle A, Metabolic Syndrome in Fasting and Non-Fasting Participants: The UAE Healthy Future Study. Int J Environ Res Public Health. 2022; 19(21):13757. doi:10.3390/ijerph192113757.Google ScholarCross Ref
- Su D, Chen Z, Chang J, Effect of Social Participation on the Physical Functioning and Depression of Empty-Nest Elderly in China: Evidence from the China Health and Retirement Longitudinal Survey (CHARLS). Int J Environ Res Public Health. 2020; 17(24):9438. doi:10.3390/ijerph17249438.Google ScholarCross Ref
- Yao S, Zhou Y, Xu L, Association between hyperuricemia and metabolic syndrome: A cross-sectional study in Tibetan adults on the Tibetan plateau. Front Endocrinol (Lausanne). 2022; 13:964872. doi:10.3389/fendo. 2022. 964872.Google ScholarCross Ref
- Saklayen MG. The Global Epidemic of the Metabolic Syndrome. Curr Hypertens Rep. 2018; 20(2):12. doi:10.1007/s11906-018-0812-z.Google ScholarCross Ref
- Ge H, Yang Z, Li X, The prevalence and associated factors of metabolic syndrome in Chinese aging population. Sci Rep. 2020; 10(1):20034. doi:10.1038/s41598-020-77184-x.Google ScholarCross Ref
- Matsubayashi K, Kimura Y, Sakamoto R, Comprehensive geriatric assessment of elderly highlanders in Qinghai, China I: activities of daily living, quality of life and metabolic syndrome. Geriatr Gerontol Int. 2009; 9(4):333-341. doi:10.1111/j.1447-0594. 2009. 00548.x.Google ScholarCross Ref
- Yisong H. Study on the prevalence of metabolic syndrome and its relationship with diet in China. Chin Center For Dis Control And Prev 2006; 4:20-3. doi:10.3321/j.issn:0512-7955. 2005. 06.007.Google ScholarCross Ref
- Azizi F, Salehi P, Etemadi A, Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study. Diabetes Res Clin Pract. 2003; 61(1):29-37. doi:10.1016/s0168-8227(03)00066-4.Google ScholarCross Ref
- Sui X, Church TS, Meriwether RA, Uric acid and the development of metabolic syndrome in women and men. Metabolism. 2008; 57(6):845-852. doi:10.1016/j.metabol. 2008. 01.030.Google ScholarCross Ref
- Khalid Mel-H. Is high-altitude environment a risk factor for childhood overweight and obesity in Saudi Arabia?. Wilderness Environ Med. 2008; 19(3):157-163. doi:10.1580/07-WEME-OR-095.1.Google ScholarCross Ref
- Khalid Mel-H. Is high-altitude environment a risk factor for childhood overweight and obesity in Saudi Arabia?. Wilderness Environ Med. 2008; 19(3):157-163. doi:10.1580/07-WEME-OR-095.1.Google ScholarCross Ref
- Blöchl M, Meissner S, Nestler S. Does depression after stroke negatively influence physical disability? A systematic review and meta-analysis of longitudinal studies. J Affect Disord. 2019; 247:45-56. doi: 10.1016/j.jad. 2018. 12.082.Google ScholarCross Ref
- Kong D, Solomon P, Dong X. Depressive Symptoms and Onset of Functional Disability Over 2 Years: A Prospective Cohort Study. J Am Geriatr Soc. 2019; 67(S3):S538-S544. doi:10.1111/jgs.15801.Google ScholarCross Ref
- Penninx BW, Leveille S, Ferrucci L, Exploring the effect of depression on physical disability: longitudinal evidence from the established populations for epidemiologic studies of the elderly. Am J Public Health. 1999; 89(9):1346-1352. doi:10.2105/ajph.89.9.1346.Google ScholarCross Ref
- Taylor WD, Aizenstein HJ, Alexopoulos GS. The vascular depression hypothesis: mechanisms linking vascular disease with depression. Mol Psychiatry. 2013; 18(9):963-974. doi:10.1038/mp. 2013. 20.Google ScholarCross Ref
- Goldsmith DR, Rapaport MH, Miller BJ. A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression. Mol Psychiatry. 2016; 21(12):1696-1709. doi:10.1038/mp.2016.3.Google ScholarCross Ref
- Lidén E, Karlsson B, Torén K, Metabolic syndrome - a risk factor for all-cause disability pension: a prospective study based on the Swedish WOLF cohort. Scand J Work Environ Health. 2020; 46(4):402-409. doi:10.5271/sjweh.3881.Google ScholarCross Ref
Index Terms
- Association between metabolic syndrome (MetS) and depression among community-dwelling super-old adults: results from the China Health and Retirement Longitudinal Study
Recommendations
The association between pulse wave velocity and metabolic syndrome of the aged
iCREATe '10: Proceedings of the 4th International Convention on Rehabilitation Engineering & Assistive TechnologyThe present study was conducted to evaluate the influences of age and gender on the results of noninvasive aortic (the common carotid to femoral artery) PWV, arm (the brachial to radial artery) PWV, and leg (the femoral to dorsalis pedis artery) PWV in ...
Internet use and depression among older adults
The findings regarding the impact of Internet use on well-being are mixed and studies are often criticized due to small samples and lack of consistency in measurement. Fewer studies have examined this issue among older adults. The purpose of this study ...
Comments