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Evaluating the impact of waning antibodies on COVID-19 reinfection and the importance of vaccines using a household epidemic model

Published: 19 June 2024 Publication History

Abstract

The COVID-19 pandemic has posed a significant threat to global health and the economy. Following the lifting of restrictions in China, a significant number of individuals have been infected. Since June 2023, there has been an increase in cases of reinfection due to waning antibodies. To explore this issue, we propose a household model based on the branching process approach to study the transmission and epidemic prevention of COVID-19 in the new phase of the pandemic. The model takes into account the impact of Infection and vaccine administration on viral load and transmission efficacy. Through numerical simulation analysis, we investigate the influence of waning antibodies among infectious cases over time on the transmission of the novel coronavirus, as well as the preventive and control capabilities of vaccine administration. The study further indicates the necessity of targeted vaccination strategies, particularly the administration of booster vaccines. Additionally, the need for enhanced public awareness and education about waning antibodies, strengthened surveillance and monitoring systems for reinfection cases, and a flexible vaccination strategy is emphasized. This research adds to the body of knowledge on COVID-19 prevention and control strategies, providing valuable recommendations for health policy.

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    ICMML '23: Proceedings of the International Conference on Mathematics and Machine Learning
    November 2023
    327 pages
    ISBN:9798400716973
    DOI:10.1145/3653724
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    Published: 19 June 2024

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